Zobrazeno 1 - 10
of 35
pro vyhledávání: '"P. J. Garvin"'
Autor:
Hannah L. Mackay, Helen R. Stone, George E. Ronson, Katherine Ellis, Alexander Lanz, Yara Aghabi, Alexandra K. Walker, Katarzyna Starowicz, Alexander J. Garvin, Patrick Van Eijk, Stefan A. Koestler, Elizabeth J. Anthony, Ann Liza Piberger, Anoop S. Chauhan, Poppy Conway-Thomas, Alina Vaitsiankova, Sobana Vijayendran, James F. Beesley, Eva Petermann, Eric J. Brown, Ruth M. Densham, Simon H. Reed, Felix Dobbs, Marco Saponaro, Joanna R. Morris
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Mammalian DNA replication relies on various DNA helicase and nuclease activities to ensure accurate genetic duplication, but how different helicase and nuclease activities are properly directed remains unclear. Here, we identify the ubiquiti
Externí odkaz:
https://doaj.org/article/28ce5cbc0af0403c82bcaf2f474d55ce
Autor:
George E. Ronson, Katarzyna Starowicz, Elizabeth J. Anthony, Ann Liza Piberger, Lucy C. Clarke, Alexander J. Garvin, Andrew D. Beggs, Celina M. Whalley, Matthew J. Edmonds, James F. J. Beesley, Joanna R. Morris
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract A synthetic lethal relationship exists between disruption of polymerase theta (Polθ), and loss of either 53BP1 or homologous recombination (HR) proteins, including BRCA1; however, the mechanistic basis of these observations are unclear. Her
Externí odkaz:
https://doaj.org/article/9fe50622466f46da85132eed80fe32f1
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Monoclonal antibodies (MAb) to members of the Small Ubiquitin-like modifier (SUMO) family are essential tools in the study of cellular SUMOylation. However, many anti-SUMO MAbs are poorly validated, and antibody matching to detection format
Externí odkaz:
https://doaj.org/article/d494bb1fca2344f7b3ce0e21e3ff61c2
Autor:
M. Golombek, N. H. Warner, J. A. Grant, E. Hauber, V. Ansan, C. M. Weitz, N. Williams, C. Charalambous, S. A. Wilson, A. DeMott, M. Kopp, H. Lethcoe-Wilson, L. Berger, R. Hausmann, E. Marteau, C. Vrettos, A. Trussell, W. Folkner, S. Le Maistre, N. Mueller, M. Grott, T. Spohn, S. Piqueux, E. Millour, F. Forget, I. Daubar, N. Murdoch, P. Lognonné, C. Perrin, S. Rodriguez, W. T. Pike, T. Parker, J. Maki, H. Abarca, R. Deen, J. Hall, P. Andres, N. Ruoff, F. Calef, S. Smrekar, M. M. Baker, M. Banks, A. Spiga, D. Banfield, J. Garvin, C. E. Newman, W. B. Banerdt
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
The InSight spacecraft landed on Mars on November 2018. Here, the authors characterize the surficial geology of the landing site and compare with observations and models derived from remote sensing data prior to landing and from ongoing in situ geoph
Externí odkaz:
https://doaj.org/article/4ddb238f4e9a41b193efa61d62e46113
Autor:
P J, Garvin, M L, Niehoff, S M, Robinson, B, Mistry, R, Esterl, T, Heisler, C, Combs, A, Berson, H, Solomon, L, Salinas-Madrigal
Publikováno v:
Transplantation. 63(2)
Free radical mediated lipid peroxidation (LPO) has been implicated in the pathogenesis of ischemic-reperfusion injury (IRI). To address the renoprotective effect(s) of LPO inhibition, the efficacy of the 21 aminosteroid U74389G was evaluated in three
Publikováno v:
Clinical transplantation. 10(3)
Combined kidney-pancreas transplantation is an effective surgical therapy for end-stage renal failure secondary to type I diabetes mellitus. However, obstructive pancreatitis and pancreaticocutaneous fistula remain significant postoperative complicat
Autor:
P J, Garvin, M L, Niehoff, S M, Robinson, T, Heisler, L, Salinas-Madrigal, J, Contis, H, Solomon
Publikováno v:
Transplantation. 61(10)
The pathophysiology of ischemia-reperfusion renal injury is mediated, in part, by the generation of the vasoconstricting prostanoid thromboxane A2 (TXA2). This study was undertaken to evaluate the renoprotective effects, as well as the optimal timing
Autor:
B, Bastani, S, Robinson, T, Heisler, G, Puntney, D, Aridge, L, Lindsey, H, Solomon, P J, Garvin
Publikováno v:
Clinical transplantation. 9(4)
A retrospective chart analysis of 200 consecutive, cyclosporine-treated, renal allograft recipients, transplanted between January 1988 and June 1992, was conducted to determine the incidence of and the etiologic variables for post-transplant hypercho
Publikováno v:
Transplantation. 52(4)
Autor:
F. R. Burton, M. E. Presti, C. G. Janney, P. J. Garvin, K. M. Murayama, R. S. Britton, B. A. Neuschwander-Tetri
Publikováno v:
Transplantation. 65:S95