Zobrazeno 1 - 10
of 24
pro vyhledávání: '"P. J. Duggan"'
Publikováno v:
Antibiotics, Vol 12, Iss 9, p 1459 (2023)
The threat to public health resulting from the emergence of antimicrobial resistance (AMR) is ever rising. One of the major bacterial pathogens at the forefront of this problem is methicillin-resistant Staphylococcus aureus, or MRSA, for which there
Externí odkaz:
https://doaj.org/article/c448e4e60e1b4e56974470ca8a5560e5
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Confined cells migrating through 3D environments are also constrained by the laws of physics, meaning for every action there must be an equal and opposite reaction for cells to achieve motion. Fascinatingly, there are several distinct molecular mecha
Externí odkaz:
https://doaj.org/article/cb25cb64d20c479481c3b47e792120e6
Autor:
Shalini K. Vinod, Nisali T. Wellege, Sara Kim, Kirsten J. Duggan, Mirette Ibrahim, Jesmin Shafiq
Publikováno v:
BMC Health Services Research, Vol 21, Iss 1, Pp 1-13 (2021)
Abstract Background Multidisciplinary team meeting (MDM) processes differ according to clinical setting and tumour site. This can impact on decision making. This study aimed to evaluate the translation of MDM recommendations into clinical practice ac
Externí odkaz:
https://doaj.org/article/fcdaf1a512a442a4a0ef5d1c5a50040b
Autor:
Anne J. Duggan
Publikováno v:
Medieval Worlds, Vol medieval worlds, Iss Volume 6. 2017, Pp 78-100 (2017)
Externí odkaz:
https://doaj.org/article/3393ff45a50d44bc98cb7eabf752ab6c
Publikováno v:
Health Promotion and Chronic Disease Prevention in Canada, Vol 36, Iss 9, Pp 185-193 (2016)
Introduction: The objective of this study was to assess bias in the body mass index (BMI) measure in the Canadian Maternity Experiences Survey (MES) and possible implications of bias on the relationship between BMI and selected pregnancy outcomes. Me
Externí odkaz:
https://doaj.org/article/ba7d66ced1654193b8920e9de293a0e7
Publikováno v:
Promotion de la santé et prévention des maladies chroniques au Canada, Vol 36, Iss 9, Pp 209-218 (2016)
Introduction : Cette étude visait à évaluer le biais dans la mesure de l’indice de masse corporelle (IMC) dans l’Enquête canadienne sur l’expérience de la maternité (ECEM) ainsi que les répercussions possibles de ce biais sur l’associa
Externí odkaz:
https://doaj.org/article/3d35ac79f9814d01bbaa0b58d6616876
Autor:
Peter J. Duggan, Kellie L. Tuck
Publikováno v:
Toxins, Vol 7, Iss 10, Pp 4175-4198 (2015)
Ziconotide (Prialt®), a synthetic version of the peptide ω-conotoxin MVIIA found in the venom of a fish-hunting marine cone snail Conus magnus, is one of very few drugs effective in the treatment of intractable chronic pain. However, its intratheca
Externí odkaz:
https://doaj.org/article/21892d83aff54ba794d77039aaca7a80
Autor:
Kay D. Beharry, Charles L. Cai, Faisal Siddiqui, Christina D’Agrosa, Anano Zangaladze, Ghassan Mustafa, Areej Qadri, Thomas J. Duggan, Jacob V. Aranda
Publikováno v:
Nutrients, Vol 12, Iss 7, p 1980 (2020)
Given the complexity of oxygen-induced retinopathy (OIR), we tested the hypothesis that combination therapies and modes of administration would synergistically optimize efficacy for prevention of OIR. Newborn rats were exposed to neonatal intermitten
Externí odkaz:
https://doaj.org/article/110012275dcf44a8a6eb12afdd9314b4
Autor:
Ellen C. Gleeson, Janease E. Graham, Sandro Spiller, Irina Vetter, Richard J. Lewis, Peter J. Duggan, Kellie L. Tuck
Publikováno v:
Marine Drugs, Vol 13, Iss 4, Pp 2030-2045 (2015)
A set of fluorophenoxyanilides, designed to be simplified analogues of previously reported ω-conotoxin GVIA mimetics, were prepared and tested for N-type calcium channel inhibition in a SH-SY5Y neuroblastoma FLIPR assay. N-type or Cav2.2 channel is
Externí odkaz:
https://doaj.org/article/2cdb44de3de74a758f7860ce4082332a
Autor:
Peter J. Duggan, Aijun Yang, Irina Vetter, Jeffrey R. McArthur, Richard J. Lewis, Kellie L. Tuck, Jonathan B. Baell, Charlotte Elisabet Tranberg
Publikováno v:
Marine Drugs, Vol 10, Iss 10, Pp 2349-2368 (2012)
The neuronal voltage-gated N-type calcium channel (Cav2.2) is a validated target for the treatment of neuropathic pain. A small library of anthranilamide-derived ω-Conotoxin GVIA mimetics bearing the diphenylmethylpiperazine moiety were prepared and
Externí odkaz:
https://doaj.org/article/db61d0b38a5f4d3080df9fe4138b8354