Zobrazeno 1 - 10
of 875
pro vyhledávání: '"P. J. Donahue"'
Autor:
Ahmad A. Toubasi, Jarrod J. Eisma, Jiacheng Wang, Habeeb F. Kazimuddin, Bryan Hernandez, Taegan Vinarsky, Caroline Gheen, Zachary Rohm, Carynn Koch, Margareta A. Clarke, Rachael Cheek, John Kramer, James Eaton, Manus J. Donahue, Francesca Bagnato
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 11, Pp 2912-2922 (2024)
Abstract Objective Paramagnetic rim lesions (PRLs) are a biomarker of chronic active lesions (CALs), and an important driver of neurological disability in multiple sclerosis (MS). The reason subtending some acute lesions evolvement into CALs is not k
Externí odkaz:
https://doaj.org/article/9f56998f082644d2a6ba15a2aaea67eb
Autor:
Melanie Leguizamon, Colin D. McKnight, Tristan Ponzo, Jason Elenberger, Jarrod J. Eisma, Alexander K. Song, Paula Trujillo, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen, Kilian Hett
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-10 (2024)
Abstract Intravenous arachnoid granulations (AGs) are protrusions of the arachnoid membrane into the venous lumen and function as contributors to the cerebrospinal fluid (CSF) flow circuit. Patients with Parkinson disease (PD) often present with accu
Externí odkaz:
https://doaj.org/article/27b4d6ccc982454ca3f3069043e82b4a
Autor:
Changbai Li, Sajjad Naeimipour, Fatemeh Rasti Boroojeni, Tobias Abrahamsson, Xenofon Strakosas, Yangpeiqi Yi, Rebecka Rilemark, Caroline Lindholm, Venkata K. Perla, Chiara Musumeci, Yuyang Li, Hanne Biesmans, Marios Savvakis, Eva Olsson, Klas Tybrandt, Mary J. Donahue, Jennifer Y. Gerasimov, Robert Selegård, Magnus Berggren, Daniel Aili, Daniel T. Simon
Publikováno v:
Small Science, Vol 4, Iss 11, Pp n/a-n/a (2024)
Hydrogels are promising materials for medical devices interfacing with neural tissues due to their similar mechanical properties. Traditional hydrogel‐based bio‐interfaces lack sufficient electrical conductivity, relying on low ionic conductivity
Externí odkaz:
https://doaj.org/article/0e7ea82d9a494d00b9dc6fa0a6937ece
Autor:
Gabriela Pierobon Mays, Kilian Hett, Jarrod Eisma, Colin D. McKnight, Jason Elenberger, Alexander K. Song, Ciaran Considine, Wesley T. Richerson, Caleb Han, Adam Stark, Daniel O. Claassen, Manus J. Donahue
Publikováno v:
Fluids and Barriers of the CNS, Vol 21, Iss 1, Pp 1-14 (2024)
Abstract Background Parkinson’s disease is characterized by dopamine-responsive symptoms as well as aggregation of α-synuclein protofibrils. New diagnostic methods assess α-synuclein aggregation characteristics from cerebrospinal fluid (CSF) and
Externí odkaz:
https://doaj.org/article/c3db04b28b15466ba8491545ab2c8ce4
Autor:
Marc D. Ferro, Christopher M. Proctor, Alexander Gonzalez, Sriram Jayabal, Eric Zhao, Maxwell Gagnon, Andrea Slézia, Jolien Pas, Gerwin Dijk, Mary J. Donahue, Adam Williamson, Jennifer Raymond, George G. Malliaras, Lisa Giocomo, Nicholas A. Melosh
Publikováno v:
AIP Advances, Vol 14, Iss 8, Pp 085109-085109-12 (2024)
Scalable electronic brain implants with long-term stability and low biological perturbation are crucial technologies for high-quality brain–machine interfaces that can seamlessly access delicate and hard-to-reach regions of the brain. Here, we crea
Externí odkaz:
https://doaj.org/article/94e3d3238e3a4977996ef8f8acf6f986
Autor:
Kilian Hett, Colin D. McKnight, Melanie Leguizamon, Jennifer S. Lindsey, Jarrod J. Eisma, Jason Elenberger, Adam J. Stark, Alexander K. Song, Megan Aumann, Ciaran M. Considine, Daniel O. Claassen, Manus J. Donahue
Publikováno v:
Fluids and Barriers of the CNS, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract Background Peri-sinus structures such as arachnoid granulations (AG) and the parasagittal dural (PSD) space have gained much recent attention as sites of cerebral spinal fluid (CSF) egress and neuroimmune surveillance. Neurofluid circulation
Externí odkaz:
https://doaj.org/article/530dea9866e74a5692c1c151d83a11d8
Autor:
Jarrod J. Eisma, Colin D. McKnight, Kilian Hett, Jason Elenberger, Caleb J. Han, Alexander K. Song, Ciaran Considine, Daniel O. Claassen, Manus J. Donahue
Publikováno v:
Fluids and Barriers of the CNS, Vol 21, Iss 1, Pp 1-13 (2024)
Abstract Background The choroid plexus functions as the blood-cerebrospinal fluid (CSF) barrier, plays an important role in CSF production and circulation, and has gained increased attention in light of the recent elucidation of CSF circulation dysfu
Externí odkaz:
https://doaj.org/article/d19b182c1aa74dad8a522a5900eb7c3c
Publikováno v:
Ecological Indicators, Vol 162, Iss , Pp 111622- (2024)
Habitat loss from human impacts can lead to functional homogenization, whereby natural communities become less diverse. Herbivorous coral reef fishes display varying specialization and unique functional roles among closely related taxa, making homoge
Externí odkaz:
https://doaj.org/article/c9b4aca3a5f14b31a86a1f913cf93b6c
Autor:
Yasmina Zeineddine, Michael A. Friedman, Evan G. Buettmann, Lovell B. Abraham, Gabriel A. Hoppock, Henry J. Donahue
Publikováno v:
npj Microgravity, Vol 9, Iss 1, Pp 1-12 (2023)
Abstract Developments in long-term space exploration necessitate advancements in countermeasures against microgravity-induced skeletal muscle loss. Astronaut data shows considerable variation in muscle loss in response to microgravity. Previous exper
Externí odkaz:
https://doaj.org/article/0be255b2b307415eb55e8ce9e328748b
Autor:
Elena Solopova, Wilber Romero-Fernandez, Hannah Harmsen, Lissa Ventura-Antunes, Emmeline Wang, Alena Shostak, Jose Maldonado, Manus J. Donahue, Daniel Schultz, Thomas M. Coyne, Andreas Charidimou, Matthew Schrag
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-8 (2023)
Abstract We report the case of a 79-year-old woman with Alzheimer’s disease who participated in a Phase III randomized controlled trial called CLARITY-AD testing the experimental drug lecanemab. She was randomized to the placebo group and subsequen
Externí odkaz:
https://doaj.org/article/980393b02c7a4f79b9007c599dd91386