Zobrazeno 1 - 10
of 10
pro vyhledávání: '"P. J. Amrolia"'
Autor:
Soumya P. Kania, Juliana M. F. Silva, Oscar J. Charles, John Booth, S. Y. Amy Cheung, James W. T. Yates, Austen Worth, Judith Breuer, Nigel Klein, Persis J. Amrolia, Paul Veys, Joseph F. Standing
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Epstein-Barr virus (EBV) establishes a lifelong latent infection in healthy humans, kept under immune control by cytotoxic T cells (CTLs). Following paediatric haematopoetic stem cell transplantation (HSCT), a loss of immune surveillance leads to opp
Externí odkaz:
https://doaj.org/article/3ef49753c2d3482aac57ff4f625d570d
Autor:
Ilaria M. Michelozzi, Jahangir Sufi, Thomas A. Adejumo, Persis J. Amrolia, Christopher J. Tape, Alice Giustacchini
Publikováno v:
STAR Protocols, Vol 3, Iss 1, Pp 101174- (2022)
Summary: Here, we present a comprehensive protocol for the generation and functional characterization of chimeric antigen receptor (CAR) T cells and their products by mass cytometry in a reproducible and scalable manner. We describe the production of
Externí odkaz:
https://doaj.org/article/01cf7f21fdd3460fb2113d0a586616ae
Autor:
C. Schuetz, J. Gerke, M. Ege, J. Walter, M. Kusters, A. Worth, J. A. Kanakry, D. Dimitrova, B. Wolska-Kuśnierz, K. Chen, E. Unal, M. Karakukcu, O. Pashchenko, J. Leiding, T. Kawai, P. J. Amrolia, D. Berghuis, J. Buechner, D. Buchbinder, M. J. Cowan, A. R. Gennery, T. Güngör, J. Heimall, M. Miano, I. Meyts, E. C. Morris, J. Rivière, S. O. Sharapova, P. J. Shaw, M. Slatter, M. Honig, P. Veys, A. Fischer, M. Cavazzana, D. Moshous, A. Schulz, M. H. Albert, J. M. Puck, A. C. Lankester, L. D. Notarangelo, B. Neven
Publikováno v:
Blood 141, 713-724 (2023)
Patients with hypomorphic mutations in the RAG1 or RAG2 gene present with either Omenn syndrome or atypical combined immunodeficiency with a wide phenotypic range. Hematopoietic stem cell transplantation (HSCT) is potentially curative, but data are s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::391459b4894750914486e9b5a718f87c
https://doi.org/10.1182/blood.2022017667
https://doi.org/10.1182/blood.2022017667
Autor:
Juliana M. F. Silva, Fani Ladomenou, Ben Carpenter, Sharat Chandra, Petr Sedlacek, Renata Formankova, Vicky Grandage, Mark Friswell, Andrew J. Cant, Zohreh Nademi, Mary A. Slatter, Andrew R. Gennery, Sophie Hambleton, Terence J. Flood, Giovanna Lucchini, Robert Chiesa, Kanchan Rao, Persis J. Amrolia, Paul Brogan, Lucy R. Wedderburn, Julie M. Glanville, Rachael Hough, Rebecca Marsh, Mario Abinun, Paul Veys
Publikováno v:
Blood Advances, Vol 2, Iss 7, Pp 777-786 (2018)
Abstract: Patients with juvenile idiopathic arthritis (JIA) can experience a severe disease course, with progressive destructive polyarthritis refractory to conventional therapy with disease-modifying antirheumatic drugs including biologics, as well
Externí odkaz:
https://doaj.org/article/be03c5eb281f42709fcd3eaff75a70fb
Autor:
Prashant Hiwarkar, Mike Hubank, Waseem Qasim, Robert Chiesa, Kimberly C. Gilmour, Aurore Saudemont, Persis J. Amrolia, Paul Veys
Publikováno v:
Blood Advances, Vol 1, Iss 24, Pp 2206-2216 (2017)
Abstract: Omission of in vivo T-cell depletion promotes rapid, thymic-independent CD4+-biased T-cell recovery after cord blood transplant. This enhanced T-cell reconstitution differs from that seen after stem cell transplant from other stem cell sour
Externí odkaz:
https://doaj.org/article/0fb098107fff4d22ab1d0489bd849bdb
Publikováno v:
Haemophilia : the official journal of the World Federation of Hemophilia. 3(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66f7785902a7a194f577d1cde0c16bb6
https://pubmed.ncbi.nlm.nih.gov/27214812
https://pubmed.ncbi.nlm.nih.gov/27214812
Autor:
Inderjeet Dokal, Phil Darbyshire, Paul Veys, George S. Vassiliou, Irene Roberts, R. Johnston, P. J. Amrolia, J. Bryon, Sarah Lawson, Jaspal Kaeda, Tom Vulliamy
Publikováno v:
British Journal of Haematology. 114:219-225
We have prospectively assessed the relative contribution of host and donor to haemopoiesis following stem cell transplantation (SCT) in children with β-thalassaemia major (n = 35), using karyotype analysis or Southern blot/polymerase chain reaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15988e020c48b958d875c28a442baab8
https://doi.org/10.1046/j.1365-2141.2001.02931.x
https://doi.org/10.1046/j.1365-2141.2001.02931.x
Publikováno v:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 13(12)
Epstein-Barr virus (EBV)-associated posttransplant lymphoproliferative disorder (PTLD) remains a major cause of morbidity and mortality after hematopoietic stem cell (HSCT) or solid organ transplant (SOT). Strategies to reconstitute immunity by adopt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::49e9b2389a2652a7be4dd70b0ecab4bb
https://pubmed.ncbi.nlm.nih.gov/24266973
https://pubmed.ncbi.nlm.nih.gov/24266973
Publikováno v:
Best practiceresearch. Clinical haematology. 14(4)
Beta-thalassaemia major and sickle-cell disease (SCD) reduce lifespan and quality of life for300000 children and young adults worldwide. The only cure for both disorders is allogeneic stem cell transplantation (SCT). The decision-making processes in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32fce1ee1405b5ce7b1a896873be20bb
https://pubmed.ncbi.nlm.nih.gov/11924923
https://pubmed.ncbi.nlm.nih.gov/11924923
Autor:
P J, Amrolia, T, Vulliamy, G, Vassiliou, S, Lawson, J, Bryon, J, Kaeda, I, Dokal, R, Johnston, P, Veys, P, Darbyshire, I A, Roberts
Publikováno v:
British journal of haematology. 114(1)
We have prospectively assessed the relative contribution of host and donor to haemopoiesis following stem cell transplantation (SCT) in children with beta-thalassaemia major (n = 35), using karyotype analysis or Southern blot/polymerase chain reactio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9ba68af1e5c50729be7c5b55a9b07379
https://pubmed.ncbi.nlm.nih.gov/11472371
https://pubmed.ncbi.nlm.nih.gov/11472371