Zobrazeno 1 - 10
of 19
pro vyhledávání: '"P. J. WEATHERS"'
Publikováno v:
Pathogens, Vol 12, Iss 2, p 227 (2023)
Mycobacterium tuberculosis (Mtb) is a deadly pathogen and causative agent of human tuberculosis, causing ~1.5 million deaths every year. The increasing drug resistance of this pathogen necessitates novel and improved treatment strategies. A crucial a
Externí odkaz:
https://doaj.org/article/fd4ab94446ed4b3f868120d48c544e35
Autor:
Brian M Gruessner, Pamela J Weathers
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0240874 (2021)
Dried-leaf Artemisia annua L. (DLA) antimalarial therapy was shown effective in prior animal and human studies, but little is known about its mechanism of action. Here IC50s and ring-stage assays (RSAs) were used to compare extracts of A. annua (DLAe
Externí odkaz:
https://doaj.org/article/7a3a36ba6aa44fc7acb5e672dde7f9b9
Publikováno v:
Frontiers in Plant Science, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/d9ff5a547c294c8fa97625bb5cab71bb
Autor:
Andrew K. Carlson, Annika F. Lintvedt, Allison N. Luchenbill, Allison M. Irwin, Samantha A. Heiler, Allison R. Kowalski, Payton S. Burger, Nadine E. Nahra, Caitlin J. Weathers, Sundeep Dhanjal, Christopher R. Yatooma
Publikováno v:
Journal of Freshwater Ecology, Vol 33, Iss 1, Pp 429-447 (2018)
Land use is continually evolving in river watersheds and riparian zones, particularly in areas containing dense human populations requiring infrastructure development. Land use planners in south-central Michigan, USA, are challenged to balance infras
Externí odkaz:
https://doaj.org/article/93603a6846b148389408bdeeb548523b
Publikováno v:
Biomolecules, Vol 10, Iss 2, p 254 (2020)
Artemisia annua L. and artemisinin, have been used for millennia to treat malaria. We used human liver microsomes (HLM) and rats to compare hepatic metabolism, tissue distribution, and inflammation attenuation by dried leaves of A. annua (DLA) and pu
Externí odkaz:
https://doaj.org/article/59ac430029464a0e93e4be1535751c79
Publikováno v:
bioRxiv
The SARS-CoV-2 (COVID-19) global pandemic continuous to infect and kill millions while rapidly evolving new variants that are more transmissible and evading vaccine-elicited antibodies. Artemisia annua L. extracts have shown potency against all previ
Publikováno v:
Molecules, Vol 15, Iss 4, Pp 2302-2318 (2010)
The biosynthesis of the valuable sesquiterpene anti-malarial, artemisinin, is known to respond to exogenous sugar concentrations. Here young Artemisia annua L. seedlings (strain YU) were used to measure the transcripts of six key genes in artemisinin
Externí odkaz:
https://doaj.org/article/c1e8113a74a14850b68aa4a1ace3b023
Autor:
Mostafa A Elfawal, Melissa J Towler, Nicholas G Reich, Douglas Golenbock, Pamela J Weathers, Stephen M Rich
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52746 (2012)
Drugs are primary weapons for reducing malaria in human populations. However emergence of resistant parasites has repeatedly curtailed the lifespan of each drug that is developed and deployed. Currently the most effective anti-malarial is artemisinin
Externí odkaz:
https://doaj.org/article/55c93b1decd9481b86fc352208f7cf0a
Publikováno v:
In Vitro Cellular & Developmental Biology - Plant. 33:306-312
Publikováno v:
Biotechnology and bioengineering. 71(4)
Carnations (Dianthus caryophyllus L.) grown in vitro often develop physiological abnormalities such as hyperhydration. The amount of hyperhydration and growth was compared between carnations grown in mist reactors and conventional semisolid microprop