Zobrazeno 1 - 10
of 50
pro vyhledávání: '"P. I. Lukienko"'
Publikováno v:
Bulletin of Experimental Biology and Medicine. 130:874-876
Publikováno v:
Bulletin of experimental biology and medicine. 130(9)
Thiamine (10(-4)-10(-6)M) inhibits lipid peroxidation in rat liver microsomes and free radical oxidation of oleic acid in vitro. Thiamine interacts with free radicals and hydroperoxides and is oxidized to thiochrome and thiamine disulfide. The antiox
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 58(1)
Autor:
M I, Bushma, P I, Lukienko
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 57(5)
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 57(4)
Publikováno v:
Voprosy meditsinskoi khimii. 39(5)
Content of cytochromes P-450 and b5 and the rate of oxidative dealkylation in liver microsomes as well as the antipyrine pharmacokinetics were normalized in rats with acute CCl4-induced hepatitis after treatment with cordiamine (diethyl nicotinamide)
Publikováno v:
Voprosy meditsinskoi khimii. 39(3)
Methotrexate (N10-methyl-4-amino-4-deoxyfolic acid), administered to rats subcutaneously at a dose of 0.25 mg/kg within 14 days, was found to decrease content of microsomal protein in liver tissue and content of cytochromes P-450 and b5 as well as th
Publikováno v:
Farmakologiia i toksikologiia. 54(4)
Three and ten days after the administration of CCl4 (subcutaneously, once, 4 ml/kg of 50% oil solution) there were found a decrease of the rate of antipyrine elimination (intravenously, 50 mg/kg) from the blood plasma, an increase of the total biliru
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 110(12)
The nicotinamide administration to rats (50 mg/kg, subcutaneously, over 5 days) increased the concentration of liver cytochrome b5, the activities of cytosol and microsomal glutathione S-transferase, UDP-glucuronosyltransferase and urinary excretion
Publikováno v:
Voprosy meditsinskoi khimii. 36(3)
Stimulation of lipid peroxidation, accompanied by a decrease in activity of UDP-glucuronyl- and glutathione-S-transferases, was observed in rat liver microsomes within one day after gamma-irradiation. Maximal alteration of the patterns studied was de