Zobrazeno 1 - 10
of 1 209
pro vyhledávání: '"P. Hintzen"'
Autor:
Patel, Ravi, Brayne, Angus, Hintzen, Rogier, Jaroslawicz, Daniel, Neculae, Georgiana, Corneil, Dane
Language models hold incredible promise for enabling scientific discovery by synthesizing massive research corpora. Many complex scientific research questions have multiple plausible answers, each supported by evidence of varying strength. However, e
Externí odkaz:
http://arxiv.org/abs/2402.04068
Autor:
Marijn N. Maas, Nurgül Bilgin, Laust Moesgaard, Jordi C. J. Hintzen, Anna Drozak, Jakub Drozak, Jacob Kongsted, Jasmin Mecinović
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The Nτ-His73 methylation of β-actin by histidine methyltransferase SETD3 is required for the integrity of the cellular cytoskeleton. Modulation of SETD3 activity in human cells facilitates cancer-like changes to the cell phenotype. SETD3 b
Externí odkaz:
https://doaj.org/article/fecfdbdb30a34ff9b436833ffe6729a7
Autor:
Jordi C. J. Hintzen, Shitanshu Devrani, Andrew J. Carrod, M. Bahadir Bayik, Daniel Tietze, Alesia A. Tietze
Publikováno v:
ACS Organic & Inorganic Au, Vol 4, Iss 5, Pp 517-525 (2024)
Externí odkaz:
https://doaj.org/article/1ee9d9999a5c4288b2d77b92455bc0f1
Autor:
Percy C. Hintzen
Publikováno v:
Compendium, Iss 5 (2024)
The paper examines horizons of possibilities for charting a course for the Caribbean to a sustainable future through a focus on the multiplicity of connections in which people and institutions of the region are involved. These possibilities, it is ar
Externí odkaz:
https://doaj.org/article/e690d152211e410cb1a9a44e11ef1ded
Autor:
Kim F H Hintzen, Lionel Blanchet, Agnieszka Smolinska, Marie-Louise Boumans, Ellen E Stobberingh, Jan W Dallinga, Tim Lubbers, Frederik-Jan van Schooten, Agnes W Boots
Publikováno v:
PLoS ONE, Vol 19, Iss 1, p e0297086 (2024)
IntroductionEarly and reliable determination of bacterial strain specificity and antibiotic resistance is critical to improve sepsis treatment. Previous research demonstrated the potential of headspace analysis of volatile organic compounds (VOCs) to
Externí odkaz:
https://doaj.org/article/06f68e7bcde74f1d942fd9d228963bfc
Akademický článek
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Publikováno v:
European Journal of Mineralogy, Vol 35, Pp 403-426 (2023)
The Black Forest hosts a wide range of hydrothermal mineralization, including fluorite–barite vein deposits. In a detailed investigation of the Finstergrund and Tannenboden deposits in the Wieden mining district (southern Black Forest), the diversi
Externí odkaz:
https://doaj.org/article/2105a6be9bae4cf58fc926206270ae16
Publikováno v:
Advanced Science, Vol 10, Iss 29, Pp n/a-n/a (2023)
Abstract Among biobased polymers, polylactic acid (PLA) is recognized as one of the most promising bioplastics to replace petrochemical‐based polymers. PLA is typically blended with other polymers such as polypropylene (PP) for improved melt proces
Externí odkaz:
https://doaj.org/article/2f17db6abb994cf3afb3ccd8dee6ab56
Autor:
Anna G. Manjón, Stefano Giustino Manzo, Stefan Prekovic, Leon Potgeter, Tom van Schaik, Ning Qing Liu, Koen Flach, Daniel Peric-Hupkes, Stacey Joosten, Hans Teunissen, Anoek Friskes, Mila Ilic, Dorine Hintzen, Vinícius H. Franceschini-Santos, Wilbert Zwart, Elzo de Wit, Bas van Steensel, René H. Medema
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113124- (2023)
Summary: Acquired drug resistance is a major problem in the treatment of cancer. hTERT-immortalized, untransformed RPE-1 cells can acquire resistance to Taxol by derepressing the ABCB1 gene, encoding for the multidrug transporter P-gP. Here, we inves
Externí odkaz:
https://doaj.org/article/7a246652a6144b62a928cb9cb12c35f2
Autor:
Jona Merx, Jordi C. J. Hintzen, Giordano Proietti, Hidde Elferink, Yali Wang, Miriam R. B. Porzberg, Daan Sondag, Nurgül Bilgin, Jin Park, Jasmin Mecinović, Thomas J. Boltje
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Posttranslational modifications (PTMs) on histone tails regulate eukaryotic gene expression by impacting the chromatin structure and by modulating interactions with other cellular proteins. One such PTM has been identified as serine and thre
Externí odkaz:
https://doaj.org/article/d417fc4ccbb649dca6141ab06c89fcda