Zobrazeno 1 - 10
of 48
pro vyhledávání: '"P. H. Sorensen"'
Autor:
Nastaran Khazamipour, Htoo Zarni Oo, Nader Al-Nakouzi, Mona Marzban, Nasrin Khazamipour, Morgan E Roberts, Negin Farivar, Igor Moskalev, Joey Lo, Fariba Ghaidi, Irina Nelepcu, Alireza Moeen, Sarah Truong, Robert Dagil, Swati Choudhary, Tobias Gustavsson, Beibei Zhai, Sabine Heitzender, Ali Salanti, Poul H Sorensen, Mads Daugaard
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 11, Pp 2775-2794 (2024)
Abstract Glycosaminoglycans are often deprioritized as targets for synthetic immunotherapy due to the complexity of glyco-epitopes and limited options for obtaining specific subtype binding. Solid tumors express proteoglycans that are modified with o
Externí odkaz:
https://doaj.org/article/d3295f9f532345a98191aa5661d49d04
Autor:
Jonathan K. M. Lim, Arash Samiei, Alberto Delaidelli, Jessica Oliveira de Santis, Vanessa Brinkmann, Christopher J. Carnie, Daniel Radiloff, Laura Hruby, Alisa Kahler, Jordan Cran, Gabriel Leprivier, Poul H. Sorensen
Publikováno v:
Cell Death and Disease, Vol 15, Iss 7, Pp 1-10 (2024)
Abstract Eukaryotic elongation factor 2 (eEF2) kinase (eEF2K) is a stress-responsive hub that inhibits the translation elongation factor eEF2, and consequently mRNA translation elongation, in response to hypoxia and nutrient deprivation. EEF2K is als
Externí odkaz:
https://doaj.org/article/6835837b84d7441fa2ee38d01cd997d9
Autor:
Ingrid Elisia, Michelle Yeung, Sara Kowalski, Taras Shyp, Jason Tee, Serena Hollman, Amy Wong, Janette King, Roger Dyer, Poul H. Sorensen, Gerald Krystal
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Given that ketogenic diets (KDs) are extremely high in dietary fat, we compared different fats in KDs to determine which was the best for cancer prevention. Specifically, we compared a Western and a 15% carbohydrate diet to seven different K
Externí odkaz:
https://doaj.org/article/57ab62a0bc3e4659ba793b9879e8ec63
Autor:
Arash Nabbi, Pengbo Beck, Alberto Delaidelli, Derek A. Oldridge, Sumedha Sudhaman, Kelsey Zhu, S. Y. Cindy Yang, David T. Mulder, Jeffrey P. Bruce, Joseph N. Paulson, Pichai Raman, Yuankun Zhu, Adam C. Resnick, Poul H. Sorensen, Martin Sill, Sebastian Brabetz, Sander Lambo, David Malkin, Pascal D. Johann, Marcel Kool, David T. W. Jones, Stefan M. Pfister, Natalie Jäger, Trevor J. Pugh
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-24 (2023)
Abstract Background Cancer immunotherapies including immune checkpoint inhibitors and Chimeric Antigen Receptor (CAR) T-cell therapy have shown variable response rates in paediatric patients highlighting the need to establish robust biomarkers for pa
Externí odkaz:
https://doaj.org/article/55f18503cc5b446bb5969c8df01fb686
Autor:
Mandy Wigdorowitz, Marton Ribary, Andrea Farina, Eleonora Lima, Daniele Borkowski, Paola Marongiu, Amanda H. Sorensen, Christelle Timis, Barbara McGillivray
Publikováno v:
Publications, Vol 12, Iss 3, p 24 (2024)
Partaking in the editorial process of an academic journal is both a challenging and rewarding experience. It takes a village of dedicated individuals with a vested interest in the dissemination and sharing of high-quality research outputs. As members
Externí odkaz:
https://doaj.org/article/1be7e7b16f5446589a1f5c15f8a0f4c1
Publikováno v:
Current Oncology, Vol 30, Iss 5, Pp 5024-5046 (2023)
In spite of recent advances in tumour molecular subtyping, pediatric brain tumours (PBTs) remain the leading cause of cancer-related deaths in children. While some PBTs are treatable with favourable outcomes, recurrent and metastatic disease for cert
Externí odkaz:
https://doaj.org/article/d3be6e31314e401f98284991090f1880
Autor:
Serena Petracchini, Daniel Hamaoui, Anne Doye, Atef Asnacios, Florian Fage, Elisa Vitiello, Martial Balland, Sebastien Janel, Frank Lafont, Mukund Gupta, Benoit Ladoux, Jerôme Gilleron, Teresa M. Maia, Francis Impens, Laurent Gagnoux-Palacios, Mads Daugaard, Poul H. Sorensen, Emmanuel Lemichez, Amel Mettouchi
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-22 (2022)
Uropathogenic strains of Escherichia coli (UPEC) are a leading cause of urinary tract infections (UTIs) and invasion involves Rho GTPase members, notably Rac1, to drive actin cytoskeleton rearrangement leading to engulfment. Here, Petracchini et al.
Externí odkaz:
https://doaj.org/article/1958110237ff42f391f49c167f39e785
Autor:
Mette Ø. Agerbæk, Sara R. Bang-Christensen, Ming-Hsin Yang, Thomas M. Clausen, Marina A. Pereira, Shreya Sharma, Sisse B. Ditlev, Morten A. Nielsen, Swati Choudhary, Tobias Gustavsson, Poul H. Sorensen, Tim Meyer, David Propper, Jonathan Shamash, Thor G. Theander, Alexandra Aicher, Mads Daugaard, Christopher Heeschen, Ali Salanti
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-4 (2022)
Externí odkaz:
https://doaj.org/article/f6392ecee1604c1c8634dfb49b15aea6
Autor:
Chris Kedong Wang, Irina Nelepcu, Desmond Hui, Htoo Zarni Oo, Sarah Truong, Sarah Zhao, Zakir Tahiry, Shaghayegh Esfandnia, Fariba Ghaidi, Hans Adomat, Robert Dagil, Tobias Gustavsson, Swati Choudhary, Ali Salanti, Poul H. Sorensen, Nader Al Nakouzi, Mads Daugaard
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Proteoglycans are proteins that are modified with glycosaminoglycan chains. Chondroitin sulfate proteoglycans (CSPGs) are currently being exploited as targets for drug-delivery in various cancer indications, however basic knowledge on how CS
Externí odkaz:
https://doaj.org/article/7acd38f75941467fad0cb73fc145ad87
Autor:
Xiaojie Chu, Du-San Baek, Wei Li, Taras Shyp, Brian Mooney, Margaret G. Hines, Gregg B. Morin, Poul H. Sorensen, Dimiter S. Dimitrov
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) is a type II transmembrane glycoprotein expressed in many tissues. High expression levels of ENPP1 have been observed in many cancer types such as lung cancer, ovarian cancer, and breast canc
Externí odkaz:
https://doaj.org/article/990d8462cff4464588159dfd68d9ec5f