rVSV-ZEBOV vaccination in people with pre-existing immunity to Ebolavirus: an open-label safety and immunogenicity study in Guinean communities affected by Ebola virus disease (l’essai proches)

Autor: Conall H. Watson, Pierre-Stéphane Gsell, Yper Hall, Anton Camacho, Ximena Riveros, Godwin Enwere, Andrea Vicari, Séverine Danmadji Nadlaou, Alhassane Toure, Ismaila M. Sani, Abdourahamane Diallo, Cece Kolie, Sophie Duraffour, Kékoura Ifono, Andre Maomou, Kassie Dore, Honora A. Djidonou, Aminata Bagayoko, Philos P. Damey, Mabetty Nancy Camara, Fatoumata Battouly Diallo, Fofana Thierno Oumar, Kalidou Toure, Mohamed Lamine Diaby, Lansana Sylla, Doussou Conde, Ibrahima Lansana Kaba, Tom Tipton, Rosalind M. Eggo, Michael Marks, Chrissy H. Roberts, Thomas Strecker, Stephan Günther, Sakoba Keita, W. John Edmunds, Miles W. Carroll, Ana Maria Henao-Restrepo

Publikováno v: BMC Medicine, Vol 22, Iss 1, Pp 1-10 (2024)

Abstract Background Zaire Ebolavirus disease (EVD) outbreaks can be controlled using rVSV-ZEBOV vaccination and other public health measures. People in high-risk areas may have pre-existing antibodies from asymptomatic Ebolavirus exposure that might

Externí odkaz: https://doaj.org/article/7edf75c9d0dc40bdb3b727714c327ce3

Predicting mortality in febrile adults: comparative performance of the MEWS, qSOFA, and UVA scores using prospectively collected data among patients in four health-care sites in sub-Saharan Africa and South-Eastern AsiaResearch in context

Autor: Sham Lal, Manophab Luangraj, Suzanne H. Keddie, Elizabeth A. Ashley, Oliver Baerenbold, Quique Bassat, John Bradley, John A. Crump, Nicholas A. Feasey, Edward W. Green, Kevin C. Kain, Ioana D. Olaru, David G. Lalloo, Chrissy h. Roberts, David C.W. Mabey, Christopher C. Moore, Heidi Hopkins, Sara Ajanovic, Benjamin Amos, Stéphanie Baghoumina, Núria Balanza, Tsitsi Bandason, Tapan Bhattacharyya, Stuart D. Blacksell, Zumilda Boca, Christian Bottomley, Justina M. Bramugy, Clare IR. Chandler, Vilada Chansamouth, Mabvuto Chimenya, Joseph Chipanga, Anelsio Cossa, Ethel Dauya, Catherine Davis, Xavier de Lamballerie, Justin Dixon, Somyoth Douangphachanh, Audrey Dubot-Pérès, Michelle M. Durkin, Rashida A. Ferrand, Colin Fink, Elizabeth JA. Fitchett, Alessandro Gerada, Stephen R. Graves, Edward Green, Becca L. Handley, Coll D. Hutchison, Risara Jaksuwan, Jessica Jervis, Jayne Jones, Khamxeng Khounpaseuth, Katharina Kranzer, Khamfong Kunlaya, Pankaj Lal, Yoel Lubell, David CW. Mabey, Eleanor MacPherson, Forget Makoga, Sengchanh Manichan, Tegwen Marlais, Florian Maurer, Mayfong Mayxay, Michael Miles, Polycarp Mogeni, Campos Mucasse, Paul N. Newton, Chelsea Nguyen, Vilayouth Phimolsarnnousith, Mathieu Picardeau, Chrissy H. Roberts, Amphone Sengduangphachanh, Siho Sengsavang, Molly Sibanda, Somvai Singha, John Stenos, Ampai Tanganuchitcharnchai, Hira Tanvir, James E. Ussher, Marta Valente, Marie A. Voice, Manivanh Vongsouvath, Msopole Wamaka, L Joseph Wheat, Shunmay Yeung

Publikováno v: EClinicalMedicine, Vol 77, Iss , Pp 102856- (2024)

Summary: Background: Clinical severity scores can identify patients at risk of severe disease and death, and improve patient management. The modified early warning score (MEWS), the quick Sequential (Sepsis-Related) Organ Failure Assessment (qSOFA),

Externí odkaz: https://doaj.org/article/472ab60c07af4c819f058bc83c88007e

Percutaneous decannulation reduces procedure length and rates of groin wound infection in patients on venoarterial extracorporeal membrane oxygenationCentral MessagePerspective

Autor: Sophia H. Roberts, MD, Erin M. Schumer, MD, Mary Sullivan, AGACNP-BC, John Grotberg, MD, Bianca Jenkins, BSN, Irene Fischer, MPH, Marci Damiano, BSN, Matthew R. Schill, MD, Muhammad F. Masood, MD, Kunal Kotkar, MD, Amit Pawale, MD

Publikováno v: JTCVS Open, Vol 18, Iss , Pp 80-86 (2024)

Objective: Open decannulation from femoral venoarterial extracorporeal membrane oxygenation (VA-ECMO) carries high risk of morbidity, including groin wound infection. This study evaluated the impact of percutaneous decannulation on rates of groin wou

Externí odkaz: https://doaj.org/article/c9ebd622ca334e22a60251b1b0a1b8d0

Molybdenum Isotope Fingerprinting of Microbial Sulfate Reduction in Seep Carbonate Rocks

Autor: Zice Jia, Yu Hu, Germain Bayon, Jörn Peckmann, Xudong Wang, Shanggui Gong, Jie Li, Harry H. Roberts, Duofu Chen, Dong Feng

Publikováno v: Geochemistry, Geophysics, Geosystems, Vol 25, Iss 3, Pp n/a-n/a (2024)

Abstract Understanding the interaction between molybdenum (Mo) and organic matter during microbial sulfate reduction is critical for the use of Mo to reconstruct marine redox conditions throughout Earth's history. However, little is known about Mo is

Externí odkaz: https://doaj.org/article/a7ce9c64471141be91dd515176d8df54

How Do Drought, Heat Stress, and Their Combination Impact Stem Reserve Mobilization in Wheat Genotypes?

Autor: Behrouz Vaezi, Ahmad Arzani, Thomas H. Roberts

Publikováno v: Agronomy, Vol 14, Iss 8, p 1867 (2024)

Drought and heat stresses represent the primary agricultural challenges in arid and semiarid regions globally. In wheat, among the most vulnerable stages to these stresses is the grain-filling process. This critical phase relies heavily on photosynth

Externí odkaz: https://doaj.org/article/29d3fce34d094dbcae5e419b8332aa98