Zobrazeno 1 - 10
of 734
pro vyhledávání: '"P. H. ROBERT"'
Autor:
A. Mouton, F. Blanc, A. Gros, V. Manera, R. Fabre, E. Sauleau, I. Gomez-Luporsi, K. Tifratene, L. Friedman, S. Thümmler, C. Pradier, P. H. Robert, R. David
Publikováno v:
Alzheimer’s Research & Therapy, Vol 10, Iss 1, Pp 1-10 (2018)
Abstract Background Gender distribution varies across neurodegenerative disorders, with, traditionally, a higher female frequency reported in Alzheimer’s disease (AD) and a higher male frequency in Parkinson’s disease (PD). Conflicting results on
Externí odkaz:
https://doaj.org/article/772f2ef400ef4e9fb20a0c281b0bd894
Autor:
Frost, H. Robert
We describe a set of network analysis methods based on the rows of the Krylov subspace matrix computed from a network adjacency matrix via power iteration using a non-random initial vector. We refer to these node-specific row vectors as Krylov subspa
Externí odkaz:
http://arxiv.org/abs/2403.01269
Autor:
Frost, H. Robert
We describe a family of iterative algorithms that involve the repeated execution of discrete and inverse discrete Fourier transforms. One interesting member of this family is motivated by the discrete Fourier transform uncertainty principle and invol
Externí odkaz:
http://arxiv.org/abs/2211.09284
Autor:
Constanza Ahumada-Marchant, Carlos Ancatén-Gonzalez, Henny Haensgen, Bastian Brauer, Nicolas Merino-Veliz, Rita Droste, Felipe Arancibia, H. Robert Horvitz, Martha Constantine-Paton, Gloria Arriagada, Andrés E. Chávez, Fernando J. Bustos
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Background The VPS50 protein functions in synaptic and dense core vesicle acidification, and perturbations of VPS50 function produce behavioral changes in Caenorhabditis elegans. Patients with mutations in VPS50 show severe developmental del
Externí odkaz:
https://doaj.org/article/ad30b723d8124e138da330532a3f6dbd
Autor:
Courtney Schiebout, H. Robert Frost
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-16 (2024)
Abstract Background A vital step in analyzing single-cell data is ascertaining which cell types are present in a dataset, and at what abundance. In many diseases, the proportions of varying cell types can have important implications for health and pr
Externí odkaz:
https://doaj.org/article/964bfd9b40a847d18511c921acd82b64
Autor:
Frost, H. Robert
We present a novel approach for computing a variant of eigenvector centrality for multilayer networks with inter-layer constraints on node importance. Specifically, we consider a multilayer network defined by multiple edge-weighted, potentially direc
Externí odkaz:
http://arxiv.org/abs/2205.01478
Autor:
H. Robert Frost
Publikováno v:
Applied Network Science, Vol 9, Iss 1, Pp 1-20 (2024)
Abstract We present a novel approach for computing a variant of eigenvector centrality for multilayer networks with inter-layer constraints on node importance. Specifically, we consider a multilayer network defined by multiple edge-weighted, potentia
Externí odkaz:
https://doaj.org/article/821bb9af2e79426fb841aaceb2af4fb8
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract How cells regulate gene expression in a precise spatiotemporal manner during organismal development is a fundamental question in biology. Although the role of transcriptional condensates in gene regulation has been established, little is kno
Externí odkaz:
https://doaj.org/article/e15ca82db36c494f82a5916eaca4ed2b
Autor:
H Robert Frost
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 4, p e1012084 (2024)
We have developed a new, and analytically novel, single sample gene set testing method called Reconstruction Set Test (RESET). RESET quantifies gene set importance based on the ability of set genes to reconstruct values for all measured genes. RESET
Externí odkaz:
https://doaj.org/article/0efb98aafb7f492390fc30946b35440f
Autor:
Frost, H. Robert
We present a novel technique for sparse principal component analysis. This method, named Eigenvectors from Eigenvalues Sparse Principal Component Analysis (EESPCA), is based on the formula for computing squared eigenvector loadings of a Hermitian mat
Externí odkaz:
http://arxiv.org/abs/2006.01924