Zobrazeno 1 - 10
of 19
pro vyhledávání: '"P. H. Nadeau"'
Autor:
Naoki Hirose, Genevieve Blanchet, Yasuhiro Yamauchi, Abigail C. Snow, Robin Friedman, Carmen Y. Khoo, Christine W. Lary, Monika A. Ward, Joseph H. Nadeau
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Meiosis, recombination, and gametogenesis normally ensure that gametes combine randomly. But in exceptional cases, fertilization depends on the genetics of gametes from both females and males. A key question is whether their non-random union
Externí odkaz:
https://doaj.org/article/9915061933394e63b97ceb1a16c648a4
Autor:
Erin Meyers, Zachary Werner, David Wichman, Hunter L. Mathews, Richard A. Radcliffe, Joseph H. Nadeau, Jerry A. Stitzel
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
The gene CHRNA5 is strongly associated with the level of nicotine consumption in humans and manipulation of the expression or function of Chrna5 similarly alters nicotine consumption in rodents. In both humans and rodents, reduced or complete loss of
Externí odkaz:
https://doaj.org/article/047a09140d1e4fe3a9f18115d9175c50
Autor:
Yujuan Gui, Mélanie H. Thomas, Pierre Garcia, Mona Karout, Rashi Halder, Alessandro Michelucci, Heike Kollmus, Cuiqi Zhou, Shlomo Melmed, Klaus Schughart, Rudi Balling, Michel Mittelbronn, Joseph H. Nadeau, Robert W. Williams, Thomas Sauter, Manuel Buttini, Lasse Sinkkonen
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Dopaminergic neurons in the midbrain are of particular interest due to their role in diseases such as Parkinson’s disease and schizophrenia. Genetic variation between individuals can affect the integrity and function of dopaminergic neurons but the
Externí odkaz:
https://doaj.org/article/54d054775e744ce8a53a0661038a6a2d
Autor:
Matthew V Cannon, David A Buchner, James Hester, Hadley Miller, Ephraim Sehayek, Joseph H Nadeau, David Serre
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90335 (2014)
Epidemiological and animal studies have shown that maternal diet can influence metabolism in adult offspring. However, the molecular mechanisms underlying these changes remain poorly understood. Here, we characterize the phenotypes induced by materna
Externí odkaz:
https://doaj.org/article/cdbab7e68d124b39a762d25e277e18ea
Autor:
Jessica A Lehoczky, Peedikayil E Thomas, Kevin M Patrie, Kailey M Owens, Lisa M Villarreal, Kenneth Galbraith, Joe Washburn, Craig N Johnson, Bryant Gavino, Alexander D Borowsky, Kathleen J Millen, Paul Wakenight, William Law, Margaret L Van Keuren, Galina Gavrilina, Elizabeth D Hughes, Thomas L Saunders, Lesil Brihn, Joseph H Nadeau, Jeffrey W Innis
Publikováno v:
PLoS Genetics, Vol 9, Iss 12, p e1003967 (2013)
Mouse early transposon insertions are responsible for ~10% of spontaneous mutant phenotypes. We previously reported the phenotypes and genetic mapping of Polypodia, (Ppd), a spontaneous, X-linked dominant mutation with profound effects on body plan m
Externí odkaz:
https://doaj.org/article/7e2168f239154d7b8e91247117543900
