Zobrazeno 1 - 10
of 11
pro vyhledávání: '"P. H. H. Hermkens"'
Autor:
Laura E. de Vries, Patrick A. M. Jansen, Catalina Barcelo, Justin Munro, Julie M. J. Verhoef, Charisse Flerida A. Pasaje, Kelly Rubiano, Josefine Striepen, Nada Abla, Luuk Berning, Judith M. Bolscher, Claudia Demarta-Gatsi, Rob W. M. Henderson, Tonnie Huijs, Karin M. J. Koolen, Patrick K. Tumwebaze, Tomas Yeo, Anna C. C. Aguiar, Iñigo Angulo-Barturen, Alisje Churchyard, Jake Baum, Benigno Crespo Fernández, Aline Fuchs, Francisco-Javier Gamo, Rafael V. C. Guido, María Belén Jiménez-Diaz, Dhelio B. Pereira, Rosemary Rochford, Camille Roesch, Laura M. Sanz, Graham Trevitt, Benoit Witkowski, Sergio Wittlin, Roland A. Cooper, Philip J. Rosenthal, Robert W. Sauerwein, Joost Schalkwijk, Pedro H. H. Hermkens, Roger V. Bonnert, Brice Campo, David A. Fidock, Manuel Llinás, Jacquin C. Niles, Taco W. A. Kooij, Koen J. Dechering
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Here, de Vries et al. perform a pre-clinical characterization of the antimalarial compound MMV693183: the compound targets acetyl-CoA synthetase, has efficacy in humanized mice against Plasmodium falciparum infection, blocks transmission to mosquito
Externí odkaz:
https://doaj.org/article/5a569da9aa694e86aa5e04aa0c21ba75
Autor:
M. Th. M. Tulp, P. H. H. Hermkens, J. H. Van Maarseveen, H. W. Scheeren, C.G. Kruse, Gerard D. H. Dijkstra
Publikováno v:
ChemInform. 24
Autor:
Van Maarseveen Jh, Jan Balzarini, Hans W. Scheeren, Chris G. Kruse, P. H. H. Hermkens, De Clercq E
Publikováno v:
Journal of Medicinal Chemistry. 35:3223-3230
The in vitro antiviral and antitumor activities of (-)-debromoeudistomin K (1a) and 10 structural analogues (1b-1j and 11) were evaluated. The synthesis was accomplished with an intramolecular Pictet-Spengler condensation reaction as the key step. Th
Autor:
P. H. H. Hermkens, Hans E. Schoemaker, J.H. van Maarseveen, K. Kirchsteiger, Henk Hiemstra, Floris P. J. T. Rutjes, Wim J. N. Meester
Publikováno v:
ARKIVOC, 2, 122-151. Arkat USA
Arkivoc, 2, 2, pp. 122-151
Arkivoc, 2, 122-151
ARKIVOC, Vol 2004, Iss 2, Pp 122-151 (2003)
Scopus-Elsevier
Arkivoc, 2, 2, pp. 122-151
Arkivoc, 2, 122-151
ARKIVOC, Vol 2004, Iss 2, Pp 122-151 (2003)
Scopus-Elsevier
The full scope and limitations of solution and solid phase one-pot three component N- acyliminium ion reactions are detailed. After studying the scope in solution with respect to the carbamate, nucleophile and aldehyde component, a 'translation' was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7746af2306030c889b5218943c0899f1
https://dare.uva.nl/personal/pure/en/publications/scope-and-limitations-of-the-solution-and-solid-phase-synthesis-of-homoallylic-amines-via-nacyliminium-ion-reactions(58b50d03-78d9-4bb9-9fae-7f09559e2347).html
https://dare.uva.nl/personal/pure/en/publications/scope-and-limitations-of-the-solution-and-solid-phase-synthesis-of-homoallylic-amines-via-nacyliminium-ion-reactions(58b50d03-78d9-4bb9-9fae-7f09559e2347).html
Autor:
P H H, Hermkens, G, Müller
Publikováno v:
Ernst Schering Research Foundation workshop. (42)
Autor:
G. Müller, P. H. H. Hermkens
Publikováno v:
Small Molecule — Protein Interactions ISBN: 9783662053164
In the early 1990s, the pharmaceutical industry had to increase its productivity of R&D as a result of market pressures within the health-care sector, which was increasingly emphasizing medical need and patient benefit (pharmaco-economics). This resu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5fab28b75db676715cf5cd6875070bd
https://doi.org/10.1007/978-3-662-05314-0_13
https://doi.org/10.1007/978-3-662-05314-0_13
Autor:
P. H. H. Hermkens, Hans W. Scheeren, C.G. Kruse, J. H. Van Maarseveen, Harry C. J. Ottenheijm
Publikováno v:
ChemInform. 21
Autor:
C.G. Kruse, H. W. Berens, P. H. H. Hermkens, Jan M. M. Smits, Hans W. Scheeren, J. H. Van Maarseveen
Publikováno v:
ChemInform. 21
Autor:
C.G. Kruse, J. H. Van Maarseveen, P. L. H. M. Cobben, Hans W. Scheeren, Harry C. J. Ottenheijm, P. H. H. Hermkens
Publikováno v:
ChemInform. 21
Autor:
W. T. Gruijters, Bas, A. C. Broeren, Maarten, L. van Delft, Floris, P. Sijbesma, Rint, H. H. Hermkens, Pedro, P. J. T. Rutjes, Floris
Publikováno v:
Organic Letters; July 2006, Vol. 8 Issue: 15 p3163-3166, 4p