Zobrazeno 1 - 10
of 42
pro vyhledávání: '"P. H. A. Quax"'
Autor:
V. F. E. D. Smolders, C. Rodríguez, I. Blanco, R. Szulcek, Wim Timens, L. Piccari, Y. Roger, X. Hu, Constanza Morén, C. Bonjoch, L. Sebastián, M. Castellà, J. Osorio, V. I. Peinado, Harm Jan Bogaard, P. H. A. Quax, M. Cascante, J. A. Barberà, O. Tura-Ceide
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Chronic thromboembolic pulmonary hypertension (CTEPH) and pulmonary arterial hypertension (PAH) are two forms of pulmonary hypertension (PH) characterized by obstructive vasculopathy. Endothelial dysfunction along with metabolic changes towa
Externí odkaz:
https://doaj.org/article/07d082571725443e8a4b358651954c32
Autor:
V. M. Baart, R. D. Houvast, L. F. de Geus-Oei, P. H. A. Quax, P. J. K. Kuppen, A. L. Vahrmeijer, C. F. M. Sier
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-18 (2020)
Abstract The urokinase plasminogen activator receptor (uPAR) plays a multifaceted role in almost any process where migration of cells and tissue-remodeling is involved such as inflammation, but also in diseases as arthritis and cancer. Normally, uPAR
Externí odkaz:
https://doaj.org/article/51d06986b4094a06a263c3b2b762cb87
Publikováno v:
Vascular Biology, Vol 6, Iss 1, Pp 1-12 (2024)
Chronic limb-threatening ischemia (CLTI) is a critical end-stage disease that leads to high amputation rates. Over the past few decades, therapeutic angiogenesis has attracted a lot of attention as a means to reduce the necessity for amputations. Esp
Externí odkaz:
https://doaj.org/article/49c09e2b85f44accb65852ab6d6314ae
Autor:
Peter Kip, Thijs J. Sluiter, Michael R. MacArthur, Ming Tao, Nicky Kruit, Sarah J. Mitchell, Jonathan Jung, Sander Kooijman, Josh Gorham, Jonathan G. Seidman, Paul H. A. Quax, Julius L. Decano, Masanori Aikawa, C. Keith Ozaki, James R. Mitchell, Margreet R. de Vries
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Short-term preoperative methionine restriction (MetR) is a promising translatable strategy to mitigate surgical injury response. However, its application to improve post-interventional vascular remodeling remains underexplored. Here we find
Externí odkaz:
https://doaj.org/article/8f299f54c6294dc69d98482c052be4d7
Autor:
Thijs J. Sluiter, Renée J. H. A. Tillie, Alwin de Jong, Jenny B. G. de Bruijn, Hendrika A. B. Peters, Remco van de Leijgraaf, Raghed Halawani, Michelle Westmaas, Lineke I. W. Starink, Paul H. A. Quax, Judith C. Sluimer, Margreet R. de Vries
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 3 (2024)
Background Intraplaque angiogenesis occurs in response to atherosclerotic plaque hypoxia, which is driven mainly by highly metabolically active macrophages. Improving plaque oxygenation by increasing macrophage hypoxic signaling, thus stimulating int
Externí odkaz:
https://doaj.org/article/ee316734ffed498780f541b5876daa8b
Autor:
Peter Kip, Ming Tao, Kaspar M. Trocha, Michael R. MacArthur, Hendrika A. B. Peters, Sarah J. Mitchell, Charlotte G. Mann, Thijs J. Sluiter, Jonathan Jung, Suzannah Patterson, Paul H. A. Quax, Margreet R. de Vries, James R. Mitchell, C. Keith Ozaki
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 22 (2020)
Background Failure rates after revascularization surgery remain high, both in vein grafts (VG) and arterial interventions. One promising approach to improve outcomes is endogenous upregulation of the gaseous transmitter‐molecule hydrogen sulfide, v
Externí odkaz:
https://doaj.org/article/25427a64176246a7bcb209f7d4840998
Autor:
Valérie Françoise Smolders, Erika Zodda, Paul H. A. Quax, Marina Carini, Joan Albert Barberà, Timothy M. Thomson, Olga Tura-Ceide, Marta Cascante
Publikováno v:
Frontiers in Molecular Biosciences, Vol 5 (2019)
Cardiovascular diseases (CVD) are the leading cause of death worldwide. CVD comprise a range of diseases affecting the functionality of the heart and blood vessels, including acute myocardial infarction (AMI) and pulmonary hypertension (PH). Despite
Externí odkaz:
https://doaj.org/article/28a38af9e2fd442bb7b289d51b4428ec
Autor:
A. Yaël Nossent, Antonius J. N. M. Bastiaansen, Erna A. B. Peters, Margreet R. de Vries, Zeen Aref, Sabine M. J. Welten, Saskia C. A. de Jager, Tineke C. T. M. van der Pouw Kraan, Paul H. A. Quax
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 3 (2017)
Background In order to identify factors that stimulate arteriogenesis after ischemia, we followed gene expression profiles in two extreme models for collateral artery formation over 28 days after hindlimb ischemia, namely “good‐responding” C57B
Externí odkaz:
https://doaj.org/article/4a6a4c5c61884c3ebb30813ea869683e
Publikováno v:
ESVS spring meeting in Leiden, May 19-20, 2017.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=r3c4b2081b22::77a3e5988a5725c94433d66e6b9c1ee0
Publikováno v:
PhD course Dutch Heart Foundation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=r3c4b2081b22::d6883891123ea113254289c08b40226d