Genomic approach to determine sources of neonatal Staphylococcus aureus infection from carriage in the Gambia

Autor: Abdoulie Bojang, Matthew Chung, Bully Camara, Isatou Jagne, Romain Guérillot, Ebrahim Ndure, Benjamin P Howden, Anna Roca, Elodie Ghedin

Publikováno v: BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-10 (2024)

Abstract Staphylococcus aureus is a major cause of neonatal infections in various anatomical sites, resulting in high morbidity and mortality in The Gambia. These clinical infections are often preceded by nasal carriage of S. aureus, a known risk fac

Externí odkaz: https://doaj.org/article/0b50949c957148b8a0b6006b808e3907

Vaccine-induced NA immunity decreases viral shedding, but does not disrupt chains of airborne transmission for the 2009 pandemic H1N1 virus in ferrets

Autor: K. M. Septer, T. A. Heinly, D. G. Sim, D. R. Patel, A. E. Roder, W. Wang, M. Chung, K. E. E. Johnson, E. Ghedin, T. C. Sutton

Publikováno v: mBio, Vol 15, Iss 10 (2024)

ABSTRACT Split-virion-inactivated influenza vaccines are formulated based on viral hemagglutinin content. These vaccines also contain the viral neuraminidase (NA) protein, but NA content is not standardized and varies between manufacturers. In clinic

Externí odkaz: https://doaj.org/article/33d601aa9367497dbda0b6a30aa64fd3

Impaired immune responses in the airways are associated with poor outcome in critically ill COVID-19 patients

Autor: Clea R. Barnett, Kelsey Krolikowski, Radu Postelnicu, Vikramjit Mukherjee, Imran Sulaiman, Matthew Chung, Luis Angel, Jun-Chieh J. Tsay, Benjamin G. Wu, Stephen T. Yeung, Ralf Duerr, Ludovic Desvignes, Kamal Khanna, Yonghua Li, Rosemary Schluger, Samaan Rafeq, Destiny Collazo, Yaa Kyeremateng, Nancy Amoroso, Deepak Pradhan, Sanchita Das, Laura Evans, Timothy M. Uyeki, Elodie Ghedin, Gregg J. Silverman, Leopoldo N. Segal, Shari B. Brosnahan

Publikováno v: ERJ Open Research, Vol 10, Iss 4 (2024)

Introduction Mounting evidence indicates that an individual's humoral adaptive immune response plays a critical role in the setting of SARS-CoV-2 infection, and that the efficiency of the response correlates with disease severity. The relationship be

Externí odkaz: https://doaj.org/article/328d2aa670f74aefa54a2b44011cd123

Effects of direct-fed microbial supplementation on performance and immune parameters of lactating dairy cows

Autor: A.O. Oyebade, S. Lee, H. Sultana, K. Arriola, E. Duvalsaint, C. Nino De Guzman, I. Fernandez Marenchino, L. Marroquin Pacheco, F. Amaro, L. Ghedin Ghizzi, L. Mu, H. Guan, K.V. Almeida, B. Rajo Andrade, J. Zhao, P. Tian, C. Cheng, Y. Jiang, J. Driver, O. Queiroz, L.F. Ferraretto, I.M. Ogunade, A.T. Adesogan, D. Vyas

Publikováno v: Journal of Dairy Science, Vol 106, Iss 12, Pp 8611-8626 (2023)

ABSTRACT: We evaluated the effects of supplementing bacterial direct-fed microbial (DFM) on performance, apparent total-tract digestibility, rumen fermentation, and immune parameters of lactating dairy cows. One hundred fourteen multiparous Holstein

Externí odkaz: https://doaj.org/article/e59d18807d3341f1b585f2cf04f894d7

Successful Versus Failed Transition From Controlled Ventilation to Pressure Support Ventilation in COVID-19 Patients: A Retrospective Cohort Study

Autor: Melisa Polo Friz, MD, Emanuele Rezoagli, MD, Bijan Safaee Fakhr, MD, Gaetano Florio, MD, Eleonora Carlesso, MS, Riccardo Giudici, MD, Clarissa Forlini, MD, Francesca Tardini, MD, Thomas Langer, MD, Matteo Laratta, MD, Giampaolo Casella, MD, Andrea Forastieri Molinari, MD, Alessandro Protti, MD, Maurizio Cecconi, MD, Luca Cabrini, MD, Emanuela Biagioni, MD, Angela Berselli, MD, Lucia Mirabella, MD, Tommaso Tonetti, MD, Edoardo De Robertis, MD, Domenico Luca Grieco, MD, Massimo Antonelli, MD, Giuseppe Citerio, MD, Roberto Fumagalli, MD, Giuseppe Foti, MD, Alberto Zanella, MD, Giacomo Grasselli, MD, Giacomo Bellani, MD, for the COVID-19 Lombardy ICU Network, Amedeo Guzzardella, Luigi Vivona, Vittorio Scaravilli, Sebastiano Colombo, Alessio Cacioppola, Matteo Brioni, Clarissa Forlini, Francesca Tardini, Thomas Langer, Matteo Laratta, Giampaolo Casella, Maria Marsili, Serena Stropeni, Valentina Cordolcini, Francesco Crimella, Alessandro Santini, Massimiliano Greco, Michele Ferrari, Giacomo Iapichino, Paolo Severgnini, Davide Maraggia, Dario Gasberti, Alessandro Motta, Irene Coloretti, Stefano Busani, Martina Tosi, Ilenia Gatto, Carlo Montalto, Alberto Biondo, Ziad Algamain, Valentina Alaimo, Livio Tullo, Francesco Paolo Padovano, Giacinto Pizzilli, Irene Cavalli, Rachele Simonte, Davide Valeri, Gennaro DePascale, Simone Carelli, Valentina Noseda, Giacomo Cimicchi, Gaia Ottonello, Rossano Ghedin, Francesco Giacalone, Tiziana Bove, Francesco Meroi, Sara Scapol, Laura Pistidda, Angela Muretti, Savino Spadaro, Gaetano Scaramuzzo, Gioconda Ferraro, Giuseppe Gagliardi, Giovanni Sabbatini, Angelo Pezzi, Gabriele Sales, Giorgia Montrucchio, Andrea Carsetti, Federico Longhini, Maria Vargas, Plinio Calligaro, Ilaria Mariani, Vanessa Zambelli, Beatrice Noè, Filippo Serra

Publikováno v: Critical Care Explorations, Vol 6, Iss 2, p e1039 (2024)

OBJECTIVES:. In patients with COVID-19 respiratory failure, controlled mechanical ventilation (CMV) is often necessary during the acute phases of the disease. Weaning from CMV to pressure support ventilation (PSV) is a key objective when the patient�

Externí odkaz: https://doaj.org/article/4b6ae8e021cf455fba1cf96f2a53600a