Zobrazeno 1 - 10
of 88
pro vyhledávání: '"P. Gehron Robey"'
Autor:
Biagio Palmisano, Rossella Labella, Samantha Donsante, Cristina Remoli, Emanuela Spica, Ilenia Coletta, Giorgia Farinacci, Michele Dello Spedale Venti, Isabella Saggio, Marta Serafini, Pamela Gehron Robey, Alessandro Corsi, Mara Riminucci
Publikováno v:
Bone Research, Vol 10, Iss 1, Pp 1-15 (2022)
Abstract The Gsα/cAMP signaling pathway mediates the effect of a variety of hormones and factors that regulate the homeostasis of the post-natal skeleton. Hence, the dysregulated activity of Gsα due to gain-of-function mutations (R201C/R201H) resul
Externí odkaz:
https://doaj.org/article/e09e355598ab44609087a3abf37ed652
Publikováno v:
Journal of Bone and Mineral Research. 9:417-421
We isolated and sequenced a cDNA encoding bovine bone sialoprotein (BSP) using a bovine cDNA library made from mRNA isolated from bone-derived cell cultures and ligated to a phage lambda gt11. One of the cDNA clones isolated from this library had a 1
Autor:
Larry W. Fisher, Pamela DenBesten, Stan Gronthos, Alan Boyde, W. Li, Natasha Cherman, Songtao Shi, Jaime S. Brahim, P. Gehron Robey
Publikováno v:
Journal of Dental Research. 81:531-535
In this study, we characterized the self-renewal capability, multi-lineage differentiation capacity, and clonogenic efficiency of human dental pulp stem cells (DPSCs). DPSCs were capable of forming ectopic dentin and associated pulp tissue in vivo. S
Autor:
Mahesh H. Mankani, I. Eichstetter, P. Gehron Robey, Paolo Bianco, T. Xu, Renato V. Iozzo, A. Corsi, Beatrice Sommer, Alan Boyde, Marian F. Young, J. Liang, Xiao Dong Chen
Publikováno v:
Scopus-Elsevier
Decorin (dcn) and biglycan (bgn), two members of the family of small leucine-rich proteoglycans (SLRPs), are the predominant proteoglycans expressed in skin and bone, respectively. Targeted disruption of the dcn gene results in skin laxity and fragil
Publikováno v:
Journal of Cellular Biochemistry. 59:151-160
In this study, we report on the cell adhesion properties of marrow stromal cells to extracellular matrix components such as collagen and noncollagenous proteins. The osteoblastic cells and their non-osteoblastic counter-parts (MBA series) from the ma
Autor:
Ermanno Bonucci, Paolo Bianco, P. Gehron Robey, Larry W. Fisher, Mara Riminucci, G. Silvestrini
Publikováno v:
Calcified Tissue International. 57:277-284
Bone sialoprotein was immunolocalized at the EM level in thin Lowicryl K4M sections of rat bone. Because of the unconventional EM morphology of the bone matrix seen in thin demineralized acrylate sections, the pattern of immunolabeling was compared w
Autor:
Jeffrey B. Kopp, P. Gehron Robey
Publikováno v:
Calcified Tissue International. 47:221-229
The efficacy of sodium fluoride therapy for osteoporosis remains controversial. Evidence from clinical studies and from animals receiving fluoride has suggested that fluoride might act on bone to increase osteoblast numbers and matrix synthesis. In o
Autor:
P. Gehron Robey, Songtao Shi, S. Batouli, Masako Miura, Jaime S. Brahim, Takeo W. Tsutsui, Stan Gronthos, Larry W. Fisher
Publikováno v:
Journal of dental research. 82(12)
The difference between stem-cell-mediated bone and dentin regeneration is not yet well-understood. Here we use an in vivo stem cell transplantation system to investigate differential regulation mechanisms of bone marrow stromal stem cells (BMSSCs) an
Autor:
P. Gehron Robey, Alessandro Corsi, Mara Riminucci, Sergei A. Kuznetsov, Paolo Bianco, Natasha Cherman
Fibrous dysplasia of bone (FD) is caused by somatic mutations of the GNAS1 gene, which lead to constitutive activation of adenylyl cyclase and overproduction of cAMP in osteogenic cells. Previous in vitro studies using nonclonal, heterogeneous strain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0022de5f603f2b8b8e68cdc96b1b7a8a
http://hdl.handle.net/11573/253553
http://hdl.handle.net/11573/253553
Autor:
Matarazzo P, Roberto Lala, Mara Riminucci, Alessandro Corsi, P. Gehron Robey, Michael T. Collins, Paolo Bianco
Publikováno v:
Molecular pathology : MP. 55(1)
In the pituitary gland, activating mutations of the GNAS1 (Gsalpha) gene at Gln227 have been identified in adrenocorticotrophin secreting, growth hormone secreting, and prolactin secreting adenomas. To date, mutations at the codon encoding R201, typi