Zobrazeno 1 - 10
of 45
pro vyhledávání: '"P. G. Welling"'
Publikováno v:
Drug Information Journal. 29:893-902
During the last 25 years, there has been considerable interest in in vitro-in vivo relationships of oral dosage forms. The advantages are obvious in terms of cost, time, and safety. This paper considers the problems involved in establishing in vitro-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::987b589ebc916c0189903f6654d65c0c
https://doi.org/10.1177/009286159502900311
https://doi.org/10.1177/009286159502900311
Autor:
P. G. Welling
Publikováno v:
Mechanisms of Drug Interactions ISBN: 9783642646584
The intent of this book is to present current information on drug interactions influencing drug absorption, distribution, elimination, and activity. Consistent with this, the original plan of the authors concerned was to present a single chapter on i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6cb7949df01bfaf0de6af6f8638f2ef
https://doi.org/10.1007/978-3-642-61015-8_3
https://doi.org/10.1007/978-3-642-61015-8_3
Autor:
P. G. Welling
Publikováno v:
Pharmacokinetics of Drugs ISBN: 9783642786822
Compared to other disciplines involved in drug discovery and development, with the possible exception of biotechnology, pharmacokinetics is a relative newcomer. If one delves into the literature one can find early articles that relate to the subject
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e535fe9a6f307cd8107c84b166056d94
https://doi.org/10.1007/978-3-642-78680-8_1
https://doi.org/10.1007/978-3-642-78680-8_1
Autor:
P. G. Welling, L. P. Balant
Publikováno v:
Pharmacokinetics of Drugs ISBN: 9783642786822
In 1982, Kalow introduced his review on “Ethnic differences in drug metabolism” by stating that: “the literature contains a number of examples of differences between populations in drug metabolizing capacity. Although this topic has been discus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c0c119de175adf871781caa1029d030
https://doi.org/10.1007/978-3-642-78680-8_8
https://doi.org/10.1007/978-3-642-78680-8_8
Publikováno v:
European Journal of Clinical Pharmacology. 30:699-704
The pharmacokinetics of bevantolol were examined following single and repeated oral doses to young and elderly volunteers. Following administration of a single 200-mg bevantolol tablet mean maximum plasma bevantolol concentrations in young and elderl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44ea53c2de76bdf5550433a7e2ff2878
https://doi.org/10.1007/bf00608218
https://doi.org/10.1007/bf00608218
Publikováno v:
Journal of Antimicrobial Chemotherapy. 6:373-379
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::693f2f8182c98d886204cab29443bac5
https://doi.org/10.1093/jac/6.3.373
https://doi.org/10.1093/jac/6.3.373
Autor:
R D Toothaker, P G Welling
Publikováno v:
Annual Review of Pharmacology and Toxicology. 20:173-199
The recent literature concerning interactions between ingested food and orally administered drugs, and the resulting effects on the rate and extent of drug absorption, has been reviewed. As was observed previously (1, 2) food has been shown to have a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc114d8cfb730a5f444f66db6ab94649
https://doi.org/10.1146/annurev.pa.20.040180.001133
https://doi.org/10.1146/annurev.pa.20.040180.001133
Publikováno v:
Antimicrobial Agents and Chemotherapy. 15:670-673
The pharmacokinetics of the broad-spectrum penicillin Bay k 4999 were studied in six healthy male volunteers. A 2-g dose was given by the intravenous route. The tissue penetration of the antibiotic was studied by both dermabrasion and blister techniq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::561d13807737d42602c1cf9a56b00da8
https://doi.org/10.1128/aac.15.5.670
https://doi.org/10.1128/aac.15.5.670
Publikováno v:
Journal of Antimicrobial Chemotherapy. 5:601-607
The pharmacology of cephradine, cephalexin and a new oral cephalosporin, cefaclor, has been compared in six volunteers. Cefaclor was absorbed rapidly and was cleared from the serum more rapidly than the other two agents. This was probably partially d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b908921c3ac6a0f9e95a8d8161e1c0b
https://doi.org/10.1093/jac/5.5.601
https://doi.org/10.1093/jac/5.5.601
Publikováno v:
Antimicrobial Agents and Chemotherapy. 26:741-744
The multiple-dose pharmacokinetics and safety of ciprofloxacin, a new quinoline carboxylic acid derivative, were evaluated in normal volunteers. The drug was administered orally every 12 h during successive 7-day periods at doses of 250, 500, and 750
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::661fdc9c20f1d982c3740d921d3aa684
https://doi.org/10.1128/aac.26.5.741
https://doi.org/10.1128/aac.26.5.741