Zobrazeno 1 - 10
of 12
pro vyhledávání: '"P. G. Varley"'
Autor:
Magdalena Malm, Rasool Saghaleyni, Magnus Lundqvist, Marco Giudici, Veronique Chotteau, Ray Field, Paul G. Varley, Diane Hatton, Luigi Grassi, Thomas Svensson, Jens Nielsen, Johan Rockberg
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-2 (2021)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/9b25893b02334dbda85e6f0d5d50fee7
Autor:
Myriam M. Ouberai, Ana L. Gomes Dos Santos, Sonja Kinna, Shimona Madalli, David C. Hornigold, David Baker, Jacqueline Naylor, Laura Sheldrake, Dominic J. Corkill, John Hood, Paolo Vicini, Shahid Uddin, Steven Bishop, Paul G. Varley, Mark E. Welland
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
The clinical potential of peptide therapeutic agents can only be fully realised once their physicochemical and pharmacokinetic properties are precisely controlled. Here the authors show a reversible peptide self-assembly strategy to control and prolo
Externí odkaz:
https://doaj.org/article/c7f770bfea9c44cf8e0311310d874e5d
For the record: Chemical modification of a variant of human MIP-1α; implications for dimer structure
Autor:
Ji-Chun Yang, Lloyd George Czaplewski, P. G. Varley, J. Fisher, P. Tan, J. T. Ashfield, T. Meyers, J. R. P. Arnold, D. Lowne, T. Dudgeon
Publikováno v:
Protein Science. 9:2047-2053
A sequence variant of human MIP-1alpha, in which Asp26 has been replaced by Al alpha, has been chemically modified by the addition of 13C-labeled methyl groups at each of the lysine residues and the N-terminus. The sites of methylation have been veri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58e1fd50775f8ef93157bf6e38e9cfda
https://doi.org/10.1110/ps.9.10.2047
https://doi.org/10.1110/ps.9.10.2047
Autor:
Brotherton D, T. Meyers, S. Cribbes, James S. Owen, Anthony M. C. Brown, S. Palan, E. Randle, Neil R. Schofield, Sue E. Craig, R Christison, S J Evans, V. Appay, Jane A. McKeating, Peter J. Morgan, M G Hunter, J. R. Fisher, C M Heyworth, Lloyd George Czaplewski, N R Woods, L A Howard, P G Varley, R Gilbert, B I Lord, P. Tan, Garrick K. Wilson, Lee D. Higgins, R M Edwards, T. Dudgeon, Jonathan P. Waltho, C. J. Craven
Publikováno v:
Journal of Biological Chemistry. 274:16077-16084
Human CC chemokines macrophage inflammatory protein (MIP)-1alpha, MIP-1beta, and RANTES (regulated on activation normal T cell expressed) self-associate to form high-molecular mass aggregates. To explore the biological significance of chemokine aggre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37a7297ae87013b09066307ed155593d
https://doi.org/10.1074/jbc.274.23.16077
https://doi.org/10.1074/jbc.274.23.16077
Publikováno v:
European Biophysics Journal. 25:437-443
Analytical ultracentrifugation (AUC) has reemerged as a powerful technique for protein characterisation. We report the pivotal role sedimentation equilibrium AUC has played in the development of macrophage inflammatory protein-1 alpha (MIP-1 alpha) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8682531e96891129ffad9d4dfc7630ee
https://doi.org/10.1007/s002490050058
https://doi.org/10.1007/s002490050058
Autor:
Brotherton D, T M Dexter, Michael George Hunter, Ajh Gearing, Lewis Pj, B I Lord, P G Varley, Stewart Craig, Richard Mark Edwards, S. Cribbes, A.H. Drummond, Lloyd George Czaplewski, Matthew John Mccourt, L. M. Wood, C M Heyworth, Lindsay Bawden
Publikováno v:
Blood. 86:4400-4408
The stem cell inhibitor, macrophage inflammatory protein-1 alpha (MIP-1 alpha) or LD78, protects multipotent hematopoietic progenitors in murine models from the cytotoxic effects of chemotherapy. Clinical use of human MIP-1 alpha during chemotherapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c0b0be715a017618d4ed69a5fdb99db
https://doi.org/10.1182/blood.v86.12.4400.bloodjournal86124400
https://doi.org/10.1182/blood.v86.12.4400.bloodjournal86124400
Publikováno v:
Bioseparation and Bioprocessing: Biochromatography, Membrane Separations, Modeling, Validation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a82f2c029966b82b7713fade73ff8f7a
https://doi.org/10.1002/9783527619641.ch27
https://doi.org/10.1002/9783527619641.ch27
Autor:
L G, Czaplewski, J, McKeating, C J, Craven, L D, Higgins, V, Appay, A, Brown, T, Dudgeon, L A, Howard, T, Meyers, J, Owen, S R, Palan, P, Tan, G, Wilson, N R, Woods, C M, Heyworth, B I, Lord, D, Brotherton, R, Christison, S, Craig, S, Cribbes, R M, Edwards, S J, Evans, R, Gilbert, P, Morgan, E, Randle, N, Schofield, P G, Varley, J, Fisher, J P, Waltho, M G, Hunter
Publikováno v:
The Journal of biological chemistry. 274(23)
Human CC chemokines macrophage inflammatory protein (MIP)-1alpha, MIP-1beta, and RANTES (regulated on activation normal T cell expressed) self-associate to form high-molecular mass aggregates. To explore the biological significance of chemokine aggre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::48762b18c9697b7baf7ab60c03d548be
https://pubmed.ncbi.nlm.nih.gov/10347159
https://pubmed.ncbi.nlm.nih.gov/10347159
Autor:
M G, Hunter, L, Bawden, D, Brotherton, S, Craig, S, Cribbes, L G, Czaplewski, T M, Dexter, A H, Drummond, A H, Gearing, C M, Heyworth, B I, Lord, M, McCourt, P G, Varley, L M, Wood, R M, Edwards, P J, Lewis
Publikováno v:
Blood. 86(12)
The stem cell inhibitor, macrophage inflammatory protein-1 alpha (MIP-1 alpha) or LD78, protects multipotent hematopoietic progenitors in murine models from the cytotoxic effects of chemotherapy. Clinical use of human MIP-1 alpha during chemotherapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0b8042d12396725510315c190a8474f1
https://pubmed.ncbi.nlm.nih.gov/8541527
https://pubmed.ncbi.nlm.nih.gov/8541527
Autor:
P G, Varley
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 22
This chapter has introduced the theory of fluorescence, and briefly shown that it is a technique with many wide and varied applications in biochemistry. It has the overall advantage of being able to carry out measurements on small amounts of sample i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dcc6c4b87565cce9fb24ae248e23c4d7
https://pubmed.ncbi.nlm.nih.gov/8312994
https://pubmed.ncbi.nlm.nih.gov/8312994