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Autor:
P. G. Spierckermann, M. Weindlmayr-G Ttel, H. Reckendorfer, M. Sperlich, G. L. T Chy, S. Schwarz, W. Feigl, H. Burgmann
Publikováno v:
British journal of anaesthesia. 69(3)
The pharmacokinetics of atracurium, which is degraded by Hofmann decomposition and ester hydrolysis, is not altered by impaired liver function. Atracurium should, therefore, be ideal for patients with hepatic failure, and is now widely used in clinic