Zobrazeno 1 - 10 of 117 pro vyhledávání: '"P. G. SAMMES"'
2
Active sites of β-lactamases from Bacillus cereus
Autor: P. G. Sammes, S. G. Waley, Hugh Allen Oliver Hill
Publikováno v: Philosophical Transactions of the Royal Society of London. B, Biological Sciences. 289:333-344
There are two extracellular β-lactamases produced by Bacillus cereus 569. One of these enzymes, β-lactamase I, is inactivated by 6-β-bromopenicillanic acid: the site of reaction is serine-44. This is a conserved amino acid residue in the other β-
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e65c61b96b254380463d0c7ebf28a35
https://doi.org/10.1098/rstb.1980.0050
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3
Kinetics of inactivation of β-lactamase I by 6 β-bromopenicillanic acid
Autor: B S Orlek, Stephen G. Waley, P G Sammes, V Knott-Hunziker
Publikováno v: Biochemical Journal. 187:797-802
The kinetics of the inactivation of beta-lactamase I from Bacillus cereus 569 by preparations of 6 alpha-bromopenicillanic acid showed unexpected features. These can be quantitatively accounted for on the basis of the inactivator being the epimer, 6
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfb45f59e47ae344956d8fc05b503e32
https://doi.org/10.1042/bj1870797
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5
Photochemical transformations—XX
Autor: P. G. Sammes, D. H. R. Barton, M. Silva
Publikováno v: Tetrahedron. 22:57-67
A partial synthesis of cincholic acid from oleanolic acid has been completed. Photolysis of the nitrite ester of 12α-hydroxyoleanolic acid acetate lactone gave inter alia the expected 27-oxime which, with nitrous acid, afforded the 27-nitrimine. Sin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::74561849d7624bef9cefcc90aa5102a2
https://doi.org/10.1016/s0040-4020(01)99095-7
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7
Decomposition of α-diazo-ketones: the oxiren–oxocarbene equilibrium
Autor: P. G. Sammes, S. A. Matlin
Publikováno v: J. Chem. Soc., Perkin Trans. 1. :2623-2630
A sensitive chemical test for the participation of oxirens in the decomposition of diazo-ketones has been developed, based on the subsequent rearrangement of oxocarbenes to αβ-unsaturated ketones. In this way oxiren participation has been demonstra
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::37f5c92e49927c3e975910b17d49b19b
https://doi.org/10.1039/p19720002623
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8
Chemical relationships between cephalosporins and penicillins
Autor: P. G. Sammes, D. H. R. Barton
Publikováno v: Proceedings of the Royal Society of London. Series B. Biological Sciences. 179:345-355
The group of antibiotics known as the penicillins have a unique position in chemistry. Not only were they the first type of antibiotic to be widely accepted in medical practice, but their manufacture provided a powerful stimulant for the growth of th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25c3dabeb4945c9867431a232d1e6137
https://doi.org/10.1098/rspb.1971.0101
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9
6 β-Bromopenicillanic acid inactivates β-lactamase I
Autor: B S Orlek, P G Sammes, V Knott-Hunziker, Stephen G. Waley
Publikováno v: Biochemical Journal. 177:365-367
The inactivation of beta-lactamase I by preparations of 6alpha-bromopenicillanic acid showed unexpected kinetic features that indicated that the active species was the 6beta-epimer. Samples containing 6beta-bromopenicillanic acid have been synthesize
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3bac991af178a9d8470c760ab2c38e29
https://doi.org/10.1042/bj1770365
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