Zobrazeno 1 - 6
of 6
pro vyhledávání: '"P. G. Ruminski"'
Autor:
I. R. Murray, Z. N. Gonzalez, J. Baily, R. Dobie, R. J. Wallace, A. C. Mackinnon, J. R. Smith, S. N. Greenhalgh, A. I. Thompson, K. P. Conroy, D. W. Griggs, P. G. Ruminski, G. A. Gray, M. Singh, M. A. Campbell, T. J. Kendall, J. Dai, Y. Li, J. P. Iredale, H. Simpson, J. Huard, B. Péault, N. C. Henderson
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
The mechanisms underlying tissue fibrosis are unclear. The authors show that mesenchymal cells expressing PDGFRβ mediate fibrosis in skeletal muscle and heart via a mechanism involving αv integrin, and that inhibitors of αv integrins attenuate fib
Externí odkaz:
https://doaj.org/article/8d98304aaf1746329d6b32e5bc823995
Publikováno v:
Biomolecules, Vol 14, Iss 8, p 1003 (2024)
The treatment of patients diagnosed with hematologic malignancies typically includes hematopoietic stem cell transplantation (HSCT) as part of a therapeutic standard of care. The primary graft source of hematopoietic stem and progenitor cells (HSPCs)
Externí odkaz:
https://doaj.org/article/759f6599140e47dd8213b3f5605bad40
Autor:
L. Pan, H. Kim, P. Lee, R. Saylor, Y. Tang, D. Tong, B. Baker, S. Kondragunta, C. Xu, M. G. Ruminski, W. Chen, J. Mcqueen, I. Stajner
Publikováno v:
Geoscientific Model Development, Vol 13, Pp 2169-2184 (2020)
Multiple observation data sets – Interagency Monitoring of Protected Visual Environments (IMPROVE) network data, the Automated Smoke Detection and Tracking Algorithm (ASDTA), Hazard Mapping System (HMS) smoke plume shapefiles and aircraft acetonitr
Externí odkaz:
https://doaj.org/article/c6368acfbb614d7ca6d4b97e23ce25a7
Inhibitors of Arg-Gly-Asp-Binding Integrins Reduce Development of Pancreatic Fibrosis in MiceSummary
Autor:
Barbara Ulmasov, Brent A. Neuschwander-Tetri, Jinping Lai, Vladimir Monastyrskiy, Trisha Bhat, Matthew P. Yates, Jonathan Oliva, Michael J. Prinsen, Peter G. Ruminski, David W. Griggs
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 2, Iss 4, Pp 499-518 (2016)
Background & Aims: Pancreatic stellate cells (PSCs) regulate the development of chronic pancreatitis (CP) and are activated by the cytokine transforming growth factor β (TGFB). Integrins of the αv family promote TGFB signaling in mice, probably
Externí odkaz:
https://doaj.org/article/9a6d1c0077404b55915eba3b895e7df1
Autor:
C P, Carron, D M, Meyer, J A, Pegg, V W, Engleman, M A, Nickols, S L, Settle, W F, Westlin, P G, Ruminski, G A, Nickols
Publikováno v:
Cancer research. 58(9)
The integrin alpha(v)beta3 interacts with the arginine-glycine-aspartic acid (RGD) tripeptide recognition sequence of a variety of extracellular matrix proteins. Recent studies show that alpha(v)beta3 plays an important role in tumor-induced angiogen
Publikováno v:
Chemischer Informationsdienst. 15