Zobrazeno 1 - 10
of 11
pro vyhledávání: '"P. G. Lavanchy"'
Publikováno v:
Journal of Medicinal Chemistry. 28:245-248
N-[2-Hydroxy-5-[2-(methylamino)ethyl]phenyl]methanesulfonamide (SK&F 102652) has been prepared and characterized pharmacologically. It is a potent agonist with an EC50 of 25 nM at alpha 1-adrenoceptors as determined in the isolated perfused rabbit ea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99b0f540220b2b225aa452185a5cfc21
https://doi.org/10.1021/jm00380a017
https://doi.org/10.1021/jm00380a017
Autor:
Rayvon Sneed, R. Z. Eby, Bernard Loev, J. W. Iii Wilson, L. S. Hostelley, Paul Elliot Bender, Jack H. Schlosser, P. G. Lavanchy, Carl D. Perchonock, Orum D. Stringer, G. Konicki, R. C. Jun. Smith, B. Y.-H. Hwang, William G. Groves
Publikováno v:
Chemischer Informationsdienst. 15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb3babe91296af983c69461cc7aa189d
https://doi.org/10.1002/chin.198406188
https://doi.org/10.1002/chin.198406188
Publikováno v:
Chemischer Informationsdienst. 17
Gemas Formelschema erhalt man das Indolon (VI), das als Dopamin-′ Rezeptor-Agonist untersucht wird.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33a608fdb290881e6640ff0dc4772728
https://doi.org/10.1002/chin.198606153
https://doi.org/10.1002/chin.198606153
Autor:
Kenneth M. Snader, R. D. Krell, P. G. Lavanchy, C. H. Kruse, P. A. Dandridge, F. E. Ali, J. G. Gleason
Publikováno v:
Chemischer Informationsdienst. 14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97ab5e11e43a56e6b5002104b5a392fd
https://doi.org/10.1002/chin.198303194
https://doi.org/10.1002/chin.198303194
Autor:
F. E. Ali, Beth W. Volpe, C. H. Kruse, Robert D. Krell, P. G. Lavanchy, J. G. Gleason, David T. Hill
Publikováno v:
Chemischer Informationsdienst. 14
As part of a study of the influence of structural modifications of N',N'-bis(aralkyl)imidodisulfamides on their ability to selectively antagonize SRS-A activity, a few conformationally constrained structures were examined. Among these derivatives hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba89f61dcb5f160ba0f6b64956799d77
https://doi.org/10.1002/chin.198310242
https://doi.org/10.1002/chin.198310242
Autor:
J P, Hieble, A C, Sulpizio, A J, Nichols, R M, DeMarinis, F R, Pfeiffer, P G, Lavanchy, R R, Ruffolo
Publikováno v:
Journal of hypertension. Supplement : official journal of the International Society of Hypertension. 4(6)
It is now recognized that two post-junctional alpha-adrenoceptors mediate vascular constriction. The vascular alpha 2-adrenoceptors seem to be particularly sensitive to circulating catecholamine levels, in contrast to the alpha 1-adrenoceptors, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0241f3c77481b6f98f3603728755ff8e
https://pubmed.ncbi.nlm.nih.gov/2886570
https://pubmed.ncbi.nlm.nih.gov/2886570
Autor:
C. H. Kruse, P. G. Lavanchy, F. E. Ali, Beth W. Volpe, J. G. Gleason, David T. Hill, Robert D. Krell
Publikováno v:
Journal of medicinal chemistry. 25(10)
As part of a study of the influence of structural modifications of N',N'-bis(aralkyl)imidodisulfamides on their ability to selectively antagonize SRS-A activity, a few conformationally constrained structures were examined. Among these derivatives hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed13d4fde7ae4fdff3bbde1c185bbc5d
https://pubmed.ncbi.nlm.nih.gov/7143363
https://pubmed.ncbi.nlm.nih.gov/7143363
Publikováno v:
Chemischer Informationsdienst. 16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da89b5cb4d86195342f06921aeccc8db
https://doi.org/10.1002/chin.198524161
https://doi.org/10.1002/chin.198524161
Autor:
P E, Bender, C D, Perchonock, W G, Groves, R C, Smith, O D, Stringer, R, Sneed, J H, Schlosser, L S, Hostelley, B Y, Hwang, R Z, Eby, G, Konicki, P G, Lavanchy, J W, Wilson, B, Loev
Publikováno v:
Journal of medicinal chemistry. 26(9)
A series of 9H-xanthen-9-amines possessing a wide variety of nitrogen substituents at C-9 was prepared for evaluation of gastric antisecretory activity. These substituents included the acetamidine, imidate, pyrimidine, thiazoline, quinuclidine, 2-hyd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e56db7ece79742a2f3c6084d428abad
https://pubmed.ncbi.nlm.nih.gov/6887196
https://pubmed.ncbi.nlm.nih.gov/6887196
Autor:
P. G. Lavanchy, Don E. Griswold, Blaine M. Sutton, Paul Elliot Bender, P. H. Offen, Michael J. DiMartino, Orum D. Stringer, K. A. Razgaitis, Donald T. Walz, David T. Hill
Publikováno v:
Journal of medicinal chemistry. 28(9)
A series of substituted 5,6-diaryl-2,3-dihydroimidazo[2,1-b]thiazoles were synthesized and evaluated in the rat adjuvant-induced arthritis and mouse oxazolone-induced contact sensitivity assays to determine the potential of these compounds for use as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c65ee4ce3305c60953b2272e19d3ee6
https://pubmed.ncbi.nlm.nih.gov/4032421
https://pubmed.ncbi.nlm.nih.gov/4032421