Zobrazeno 1 - 10
of 248
pro vyhledávání: '"P. G. Connolly"'
Autor:
Sudha R. Raman, Bradley G. Hammill, Pamela A. Shaw, Hana Lee, Sengwee Toh, John G. Connolly, Kimberly J. Dandreo, Vinit Nalawade, Fang Tian, Wei Liu, Jie Li, José J. Hernández-Muñoz, Robert J. Glynn, Rishi J. Desai, Janick Weberpals
Publikováno v:
BMC Medical Research Methodology, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Background Missing data in confounding variables present a frequent challenge in generating evidence using real-world data, including electronic health records (EHR). Our objective was to apply a recently published toolkit for characterizing
Externí odkaz:
https://doaj.org/article/4ae0b29ad6134def83c0064c37302018
Autor:
Olga Tymofiyeva, Tiffany C. Ho, Colm G. Connolly, Sasha Gorrell, Ryan Rampersaud, Sabrina M. Darrow, Jeffrey E. Max, Tony T. Yang
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
IntroductionSuicide is a current leading cause of death in adolescents and young adults. The neurobiological underpinnings of suicide risk in youth, however, remain unclear and a brain-based model is lacking. In adult samples, current models highligh
Externí odkaz:
https://doaj.org/article/188209985ed34321ad21cd78e2fdc894
Autor:
Vladimir Belov, Tracy Erwin-Grabner, Moji Aghajani, Andre Aleman, Alyssa R. Amod, Zeynep Basgoze, Francesco Benedetti, Bianca Besteher, Robin Bülow, Christopher R. K. Ching, Colm G. Connolly, Kathryn Cullen, Christopher G. Davey, Danai Dima, Annemiek Dols, Jennifer W. Evans, Cynthia H. Y. Fu, Ali Saffet Gonul, Ian H. Gotlib, Hans J. Grabe, Nynke Groenewold, J Paul Hamilton, Ben J. Harrison, Tiffany C. Ho, Benson Mwangi, Natalia Jaworska, Neda Jahanshad, Bonnie Klimes-Dougan, Sheri-Michelle Koopowitz, Thomas Lancaster, Meng Li, David E. J. Linden, Frank P. MacMaster, David M. A. Mehler, Elisa Melloni, Bryon A. Mueller, Amar Ojha, Mardien L. Oudega, Brenda W. J. H. Penninx, Sara Poletti, Edith Pomarol-Clotet, Maria J. Portella, Elena Pozzi, Liesbeth Reneman, Matthew D. Sacchet, Philipp G. Sämann, Anouk Schrantee, Kang Sim, Jair C. Soares, Dan J. Stein, Sophia I. Thomopoulos, Aslihan Uyar-Demir, Nic J. A. van der Wee, Steven J. A. van der Werff, Henry Völzke, Sarah Whittle, Katharina Wittfeld, Margaret J. Wright, Mon-Ju Wu, Tony T. Yang, Carlos Zarate, Dick J. Veltman, Lianne Schmaal, Paul M. Thompson, Roberto Goya-Maldonado, the ENIGMA Major Depressive Disorder working group
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Machine learning (ML) techniques have gained popularity in the neuroimaging field due to their potential for classifying neuropsychiatric disorders. However, the diagnostic predictive power of the existing algorithms has been limited by smal
Externí odkaz:
https://doaj.org/article/da78bdb629a3452faf57ce1549e6ab7a
Autor:
Sean Hennessy, Rebecca A Hubbard, Vincent Lo Re, Dena M Carbonari, Claudia A Steiner, Yunping Zhou, Cheryl N McMahill-Walraven, Pamala A Pawloski, Laura Hou, Sarah K Dutcher, John G Connolly, Silvia Perez-Vilar, Terese A DeFor, Djeneba Audrey Djibo, Laura B Harrington, Maria E Kempner, Jennifer L Kuntz, Jolene Mosley, Andrew B Petrone, Allyson M Pishko, Meighan Rogers Driscoll, Noelle M Cocoros
Publikováno v:
BMJ Medicine, Vol 2, Iss 1 (2023)
Objective To measure the 90 day risk of arterial thromboembolism and venous thromboembolism among patients diagnosed with covid-19 in the ambulatory (ie, outpatient, emergency department, or institutional) setting during periods before and during cov
Externí odkaz:
https://doaj.org/article/2491d0112e4f451494c117e8637225d9
Autor:
Brittany M. Brems, Erin E. Sullivan, Jenna G. Connolly, Jingchun Zhang, Arnold Chang, Richard Ortiz, Lucas Cantwell, Praveen Kulkarni, Ganesh A. Thakur, Craig F. Ferris
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
BackgroundAlpha 7 nicotinic acetylcholine receptor (α7nAChR) agonists have been developed to treat schizophrenia but failed in clinical trials due to rapid desensitization. GAT107, a type 2 allosteric agonist-positive allosteric modulator (ago-PAM)
Externí odkaz:
https://doaj.org/article/0eedf5d674d74d6d9c71bd536849d86c
Autor:
Yu Xu, Yuchen Yang, Aishwarya Chandrashekar, Kirin D. Gada, Meghan Masotti, Austin M. Baggetta, Jenna G. Connolly, Takeharu Kawano, Leigh D. Plant
Publikováno v:
iScience, Vol 25, Iss 9, Pp 104969- (2022)
Summary: Cardiovascular diseases remain the leading cause of death worldwide. Most deaths are sudden and occur secondary to the occlusion of coronary arteries resulting in a rapid decrease in cellular oxygen levels. Acute hypoxia is proarrhythmic, le
Externí odkaz:
https://doaj.org/article/ea4610ea29784b029883e64fd4901ee5
Autor:
Raul Caso, James G. Connolly, Jian Zhou, Kay See Tan, James J. Choi, Gregory D. Jones, Brooke Mastrogiacomo, Francisco Sanchez-Vega, Bastien Nguyen, Gaetano Rocco, Daniela Molena, Smita Sihag, Prasad S. Adusumilli, Matthew J. Bott, David R. Jones
Publikováno v:
npj Precision Oncology, Vol 5, Iss 1, Pp 1-8 (2021)
Abstract While next-generation sequencing (NGS) is used to guide therapy in patients with metastatic lung adenocarcinoma (LUAD), use of NGS to determine pathologic LN metastasis prior to surgery has not been assessed. To bridge this knowledge gap, we
Externí odkaz:
https://doaj.org/article/20e2c3f365ef4a4b89f96ace034d68c1
Autor:
Felipe A. Jain, Sergey Chernyak, Lisa Nickerson, Michelle Abrams, Marco Iacoboni, Leonardo Christov-Moore, Colm G. Connolly, Lauren B. Fisher, Hitoshi Sakurai, Kate Bentley, Emily Tan, Michael Pittman, Helen Lavretsky, Andrew F. Leuchter
Publikováno v:
Journal of Affective Disorders Reports, Vol 5, Iss , Pp 100155- (2021)
Background: Family dementia caregivers experience high rates of depression and anxiety that often go untreated due to time demands. We aimed to determine the feasibility of a brief, 4-week Mentalizing Imagery Therapy intervention, which couples mindf
Externí odkaz:
https://doaj.org/article/6abf34137ef1400f8f2a028810bb0a3e
Autor:
Olga Tymofiyeva, Eva Henje, Justin P. Yuan, Chiung-Yu Huang, Colm G. Connolly, Tiffany C. Ho, Sarina Bhandari, Kendall C. Parks, Benjamin S. Sipes, Tony T. Yang, Duan Xu
Publikováno v:
NeuroImage: Clinical, Vol 29, Iss , Pp 102521- (2021)
Mindfulness-based approaches show promise to improve emotional health in youth and may help treat and prevent adolescent depression and anxiety. However, there is a fundamental gap in understanding the neural reorganization that takes place as a resu
Externí odkaz:
https://doaj.org/article/377e35fd8ac243b58980366b7f09c0a1
Autor:
Justin P. Yuan, Colm G. Connolly, Eva Henje, Leo P. Sugrue, Tony T. Yang, Duan Xu, Olga Tymofiyeva
Publikováno v:
Frontiers in Human Neuroscience, Vol 14 (2020)
Meditation has shown to benefit a wide range of conditions and symptoms, but the neural mechanisms underlying the practice remain unclear. Magnetic resonance imaging (MRI) studies have investigated the structural brain changes due to the practice by
Externí odkaz:
https://doaj.org/article/b09192c0275c40a3bbdd760d2f1e8610