Zobrazeno 1 - 10
of 15
pro vyhledávání: '"P. G. Aparin"'
Autor:
S. V. Korobova, G. V. Kornilaeva, V. A. Toporova, I. A. Nikolaeva, L. P. Trubcheninova, N. F. Trefilyeva, L. P. Sizyakina, I. G. Sidorovich, P. G. Aparin, R. M. Khaitov
Publikováno v:
Медицинская иммунология, Vol 18, Iss 1, Pp 51-62 (2016)
The development of HIV vaccine remains an important goal in prophylaxis and therapy of HIV/ AIDS epidemics. There are various approaches for development of а candidate vaccine based on induction of neutralizing antibodies and cell-mediated immunity.
Externí odkaz:
https://doaj.org/article/1dad465a38384ed38d959bfb023cd5fb
Autor:
V. A. Lyodov, P. G. Aparin
Publikováno v:
Acta Biomedica Scientifica, Vol 0, Iss 4, Pp 91-95 (2014)
The article presents the results of the I phase of clinical trials of a vaccine preparationfor prevention of Flexner dysentery on the basis of modified Shigella flexneri lipopolysaccharide on the limited contingent of adult volunteers (26 persons). S
Externí odkaz:
https://doaj.org/article/db91a2dac1da4b1db35df80eb65dcba7
A Pentavalent Shigella flexneri LPS-Based Vaccine Candidate Is Safe and Immunogenic in Animal Models
Autor:
Vladimir A. Ledov, Marina E. Golovina, Biana I. Alkhazova, Vyacheslav L. Lvov, Alexander L. Kovalchuk, Petr G. Aparin
Publikováno v:
Vaccines, Vol 11, Iss 2, p 345 (2023)
A multivalent vaccine is much needed to achieve protection against predominant Shigella serotypes. Recently, we demonstrated the clinical applicability and immunogenic potential of tri-acylated S. flexneri 2a lipopolysaccharide (Ac3-S-LPS). Using a s
Externí odkaz:
https://doaj.org/article/64240cfa51ae4315a0e191fd316d5475
Autor:
Ivan A. Dyatlov, Edward A. Svetoch, Anna A. Mironenko, Boris V. Eruslanov, Victoria V. Firstova, Nadezhda K. Fursova, Alexander L. Kovalchuk, Vyacheslav L. Lvov, Petr G. Aparin
Publikováno v:
Vaccines, Vol 10, Iss 11, p 1854 (2022)
Background: Shiga toxin-producing Escherichia coli (STEC) O157:H7 and O104:H4 strains are important causative agents of food-borne diseases such as hemorrhagic colitis and hemolytic–uremic syndrome, which is the leading cause of kidney failure and
Externí odkaz:
https://doaj.org/article/9dd03d9af2c84858a83121948bf26d4a
Autor:
Svetlana S. Kurashova, Aidar A. Ishmukhametov, Tamara K. Dzagurova, Maria S. Egorova, Maria V. Balovneva, Nikolai A. Nikitin, Ekaterina A. Evtushenko, Olga V. Karpova, Anna A. Markina, Peter G. Aparin, Petr E. Tkachenko, Vyatcheslav L. L`vov, Evgeniy A. Tkachenko
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Various adjuvant effects on the immunogenicity of the candidate inactivated Puumala virus vaccine were detected in BALB/c mice. Adjuvants under study were: aluminum hydroxide, spherical particles of Tobacco mosaic virus coat protein, B subunit of hea
Externí odkaz:
https://doaj.org/article/9841164a3fcd4f89853799e491cbe987
Publikováno v:
Journal of Pharmacological Sciences, Vol 125, Iss 4, Pp 422-425 (2014)
Abstract.: Septic shock and associated vascular hyporeactivity to vasoconstrictor agonists remain a major problem of critical care medicine. Here we report that glycyrrhetinic acid (GA), the active component of licorice, effectively restores vascular
Externí odkaz:
https://doaj.org/article/c3a611458f0443d9a9fb450a41c57224
Autor:
M. E. Shekht, P. G. Aparin, Yu. A. Knirel, E. V. Vinogradov, A.A. Markina, Vyacheslav L. L'vov, B. Lindner, Anna N. Kondakova
Publikováno v:
Scopus-Elsevier
The full structure of the lipopolysaccharide core of bacteria Shigella flexneri types 2a and 5b, the causative agents of bacillary dysentery (shigellosis), was established by chemical methods, high-resolution electrospray ionization mass spectrometry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e562f7d0b68dead64e71cac1c6ea3b4e
https://doi.org/10.1134/s1068162010030179
https://doi.org/10.1134/s1068162010030179
Publikováno v:
Russian Journal of Bioorganic Chemistry. 28:58-61
For use in differential diagnostics of typhoid fever, samples of the capsular polysaccharide from Salmonella enterica serovar Typhi (usually named Vi-antigen) were isolated and characterized by physicochemical and serological methods. It was shown th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ca25c88897ea86e0fdb73b25b77a2cf
https://doi.org/10.1023/a:1013958320536
https://doi.org/10.1023/a:1013958320536
Autor:
N P, Vaneeva, D S, Vorob'ev, N V, Grishchenko, E A, Kurbatova, N E, Iastrebova, N G, Kalina, S I, Elkina, A V, Zubkov, P G, Aparin, V L, L'vov, N A, Mikhaĭlova
Publikováno v:
Zhurnal mikrobiologii, epidemiologii i immunobiologii. (5)
Study cross-activity of S. pneumoniae antigen preparations.Antigen preparations were obtained by ultrasound disintegration (from bacteria in R-form), extraction with water (from serotype 3 bacteria), cetavlon and trichloroacetic acid (from serotype 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::43be4717c887f9f43f1afefb299d6539
https://pubmed.ncbi.nlm.nih.gov/23163034
https://pubmed.ncbi.nlm.nih.gov/23163034
Publikováno v:
Bioorganicheskaia khimiia. 28(1)
For use in differential diagnostics of typhoid fever, samples of the capsular polysaccharide from Salmonella enterica serovar Typhi (usually named Vi-antigen) were isolated and characterized by physicochemical and serological methods. It was shown th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aaac98f4e4d288ebaa0f5dc1647b5aca
https://pubmed.ncbi.nlm.nih.gov/11875976
https://pubmed.ncbi.nlm.nih.gov/11875976