Zobrazeno 1 - 10
of 54
pro vyhledávání: '"P. G Stone"'
Autor:
Luopin Wang, Aryamav Pattnaik, Subhransu Sekhar Sahoo, Ella G. Stone, Yuxin Zhuang, Annaleigh Benton, Md Tajmul, Srishti Chakravorty, Deepika Dhawan, My An Nguyen, Isabella Sirit, Kyle Mundy, Christopher J. Ricketts, Marco Hadisurya, Garima Baral, Samantha L. Tinsley, Nicole L. Anderson, Smriti Hoda, Scott D. Briggs, Hristos Z. Kaimakliotis, Brittany L. Allen-Petersen, W. Andy Tao, W. Marston Linehan, Deborah W. Knapp, Jason A. Hanna, Matthew R. Olson, Behdad Afzali, Majid Kazemian
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Correctly identifying perturbed biological pathways is a critical step in uncovering basic disease mechanisms and developing much-needed therapeutic strategies. However, whether current tools are optimal for unbiased discovery of relevant pa
Externí odkaz:
https://doaj.org/article/37aa067c964242d3a201f09242539e89
Autor:
Katherine A. Flack, Emma S. Rainey, Sarah J. Urasa, Sengua Koipapi, Rajesh N. Kalaria, William P. Howlett, Elizabeta B. Mukaetova-Ladinska, Marieke C. J. Dekker, William K. Gray, Richard W. Walker, Catherine L. Dotchin, Himidi Mtwaile, Thomas C. D. Lewis, Lydia G. Stone, Richard J. Q. McNally, Philip C. Makupa, Stella-Maria Paddick
Publikováno v:
Viruses, Vol 16, Iss 6, p 819 (2024)
HIV-associated neurocognitive disorders (HAND) are highly prevalent in those ageing with HIV. High-income country data suggest that vascular risk factors (VRFs) may be stronger predictors of HAND than HIV-disease severity, but data from sub-Saharan A
Externí odkaz:
https://doaj.org/article/c6a092b178304b21a9a5aaab42f54f4c
Publikováno v:
European Respiratory Review, Vol 32, Iss 170 (2023)
Methicillin-resistant Staphylococcus aureus (MRSA) is responsible for an array of problematic community- and healthcare-acquired infections, including pneumonia, and is frequently associated with severe disease and high mortality rates. Standard reco
Externí odkaz:
https://doaj.org/article/0e4c1d50bce245bda4e63deb127ddc71
Autor:
Matthew Dryden, Michal Kantecki, Jean Li Yan, Gregory G. Stone, Heidi Leister-Tebbe, Mark Wilcox
Publikováno v:
Journal of Global Antimicrobial Resistance, Vol 28, Iss , Pp 108-114 (2022)
ABSTRACT: Objectives: This exploratory pooled analysis assessed the efficacy and safety of ceftaroline fosamil and comparators across six phase III clinical trials in adults with community-acquired pneumonia (CAP) or complicated skin and soft-tissue
Externí odkaz:
https://doaj.org/article/9b91dfa17c6e4c0f8d6a9988707d2d8a
Autor:
Gregory G. Stone, Meredith A. Hackel
Publikováno v:
Annals of Clinical Microbiology and Antimicrobials, Vol 21, Iss 1, Pp 1-9 (2022)
Abstract Background Increases in resistance to fluoroquinolones have been correlated with the use of levofloxacin in the treatment of infections caused by Escherichia coli. The analysis presents the in vitro activity of ceftazidime-avibactam and comp
Externí odkaz:
https://doaj.org/article/69329cc2a18e48abbe0bcfe8edbeeee7
Publikováno v:
Journal of Global Antimicrobial Resistance, Vol 27, Iss , Pp 132-141 (2021)
ABSTRACT: Objectives: This study reports the antimicrobial activity of ceftazidime/avibactam (CZA) and comparators against carbapenemase-producing Enterobacterales (N = 1992) and carbapenemase-producing Pseudomonas aeruginosa (N = 784) collected in A
Externí odkaz:
https://doaj.org/article/8f14d81feba64185bf4196ed583f7f7b
Publikováno v:
Hydrology and Earth System Sciences, Vol 25, Pp 5603-5621 (2021)
This study employs a stochastic hydrologic modeling framework to evaluate the sensitivity of flood frequency analyses to different components of the hydrologic modeling chain. The major components of the stochastic hydrologic modeling chain, includin
Externí odkaz:
https://doaj.org/article/e06e807c9d954537908af164eede2315
Autor:
Matthew T. Duggan, Melissa F. Groleau, Ethan P. Shealy, Lillian S. Self, Taylor E. Utter, Matthew M. Waller, Bryan C. Hall, Chris G. Stone, Layne L. Anderson, Timothy A. Mousseau
Publikováno v:
Ecology and Evolution, Vol 11, Iss 17, Pp 12051-12063 (2021)
Abstract Camera traps have become an extensively utilized tool in ecological research, but the manual processing of images created by a network of camera traps rapidly becomes an overwhelming task, even for small camera trap studies. We used transfer
Externí odkaz:
https://doaj.org/article/b9611a39a70546e8b6259cd0762b3a3c
Autor:
Denis Piérard, Gregory G. Stone
Publikováno v:
Journal of Global Antimicrobial Resistance, Vol 26, Iss , Pp 4-10 (2021)
ABSTRACT: Objectives: This study reports the antimicrobial activities of ceftaroline and comparators against bacterial isolates from patients with skin and skin-structure infections (2015–2018). Methods: A central laboratory performed antimicrobial
Externí odkaz:
https://doaj.org/article/fd84563203ce49aeaa70b7e6a703d75b
Autor:
Shin-ichi Oka, Karthi Sreedevi, Thirupura S. Shankar, Shreya Yedla, Sumaita Arowa, Amina James, Kathryn G. Stone, Katia Olmos, Amira D. Sabry, Amanda Horiuchi, Keiko M. Cawley, Sean A. O’very, Mingming Tong, Jaemin Byun, Xiaoyong Xu, Sanchita Kashyap, Youssef Mourad, Omair Vehra, Dallen Calder, Ty Lunde, Tong Liu, Hong Li, J. Alan Mashchek, James Cox, Yukio Saijoh, Stavros G. Drakos, Junco S. Warren
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
AimsPERM1 is a striated muscle-specific regulator of mitochondrial bioenergetics. We previously demonstrated that PERM1 is downregulated in the failing heart and that PERM1 positively regulates metabolic genes known as targets of the transcription fa
Externí odkaz:
https://doaj.org/article/3ebf8c90ae564ca6a5a114f14cb65ce0