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Autor:
OpenAI, Hurst, Aaron, Lerer, Adam, Goucher, Adam P., Perelman, Adam, Ramesh, Aditya, Clark, Aidan, Ostrow, AJ, Welihinda, Akila, Hayes, Alan, Radford, Alec, Mądry, Aleksander, Baker-Whitcomb, Alex, Beutel, Alex, Borzunov, Alex, Carney, Alex, Chow, Alex, Kirillov, Alex, Nichol, Alex, Paino, Alex, Renzin, Alex, Passos, Alex Tachard, Kirillov, Alexander, Christakis, Alexi, Conneau, Alexis, Kamali, Ali, Jabri, Allan, Moyer, Allison, Tam, Allison, Crookes, Amadou, Tootoochian, Amin, Tootoonchian, Amin, Kumar, Ananya, Vallone, Andrea, Karpathy, Andrej, Braunstein, Andrew, Cann, Andrew, Codispoti, Andrew, Galu, Andrew, Kondrich, Andrew, Tulloch, Andrew, Mishchenko, Andrey, Baek, Angela, Jiang, Angela, Pelisse, Antoine, Woodford, Antonia, Gosalia, Anuj, Dhar, Arka, Pantuliano, Ashley, Nayak, Avi, Oliver, Avital, Zoph, Barret, Ghorbani, Behrooz, Leimberger, Ben, Rossen, Ben, Sokolowsky, Ben, Wang, Ben, Zweig, Benjamin, Hoover, Beth, Samic, Blake, McGrew, Bob, Spero, Bobby, Giertler, Bogo, 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Markov, Todor, Sherbakov, Toki, Rubin, Tom, Stasi, Tom, Kaftan, Tomer, Heywood, Tristan, Peterson, Troy, Walters, Tyce, Eloundou, Tyna, Qi, Valerie, Moeller, Veit, Monaco, Vinnie, Kuo, Vishal, Fomenko, Vlad, Chang, Wayne, Zheng, Weiyi, Zhou, Wenda, Manassra, Wesam, Sheu, Will, Zaremba, Wojciech, Patil, Yash, Qian, Yilei, Kim, Yongjik, Cheng, Youlong, Zhang, Yu, He, Yuchen, Zhang, Yuchen, Jin, Yujia, Dai, Yunxing, Malkov, Yury
GPT-4o is an autoregressive omni model that accepts as input any combination of text, audio, image, and video, and generates any combination of text, audio, and image outputs. It's trained end-to-end across text, vision, and audio, meaning all inputs
Externí odkaz:
http://arxiv.org/abs/2410.21276
Autor:
Bendahi, Abderrahim, Fradin, Adrien
Finding a shortest path in a graph is one of the most classic problems in algorithmic and graph theory. While we dispose of quite efficient algorithms for this ordinary problem (like the Dijkstra or Bellman-Ford algorithms), some slight variations in
Externí odkaz:
http://arxiv.org/abs/2408.00899
Autor:
Fradin, Théo
This article is concerned with the well-posedness of the incompressible Euler equations describing a stably stratified ocean, reformulated in isopycnal coordinates. Our motivation for using this reformulation is twofold: first, its quasi-2D structure
Externí odkaz:
http://arxiv.org/abs/2406.13263
Autor:
Sommer Holmes, Hui Li, Xiaoying Shen, Mitchell Martin, Ryan Tuck, Yue Chen, Elena E. Giorgi, Hélène Fradin Kirshner, Madison Berry, Elizabeth Van Italie, Sravani Venkatayogi, Joshua S. Martin Beem, Robert J. Edwards, Katayoun Mansouri, Ajay Singh, Cindy Kuykendall, Thaddeus Gurley, M. Anthony Moody, Nicole DeNayer, Todd Demarco, Thomas N. Denny, Yunfei Wang, Tyler D. Evangelous, John T. Clinton, Bhavna Hora, Kshitij Wagh, Michael S. Seaman, Kevin O. Saunders, Nicholas Solomotis, Johnathan Misamore, Mark G. Lewis, Kevin Wiehe, David C. Montefiori, George M. Shaw, Wilton B. Williams
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract The details of the pediatric immune system that supports induction of antibodies capable of neutralizing geographically-diverse or heterologous HIV-1 is currently unclear. Here we explore the pediatric immune environment in neonatal macaque
Externí odkaz:
https://doaj.org/article/8a02ed03cb6c4c07b1bf35351c55e38c
Essential magnetosome proteins MamI and MamL from magnetotactic bacteria interact in mammalian cells
Autor:
Qin Sun, Liu Yu, Sarah C. Donnelly, Cécile Fradin, R. Terry Thompson, Frank S. Prato, Donna E. Goldhawk
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract To detect cellular activities deep within the body using magnetic resonance platforms, magnetosomes are the ideal model of genetically-encoded nanoparticles. These membrane-bound iron biominerals produced by magnetotactic bacteria are highly
Externí odkaz:
https://doaj.org/article/ad88c05c7c07482db8e7d1194db473a0
Autor:
Maureen Labbé, Manon Chang, Benjamin Saintpierre, Franck Letourneur, Laurence de Beaurepaire, Joëlle Véziers, Sophie Deshayes, Marine Cotinat, Jean-François Fonteneau, Christophe Blanquart, Vincent Potiron, Stéphane Supiot, Delphine Fradin
Publikováno v:
Cell Death and Disease, Vol 15, Iss 10, Pp 1-12 (2024)
Abstract Radiotherapy represents a major curative treatment for prostate cancer (PCa), but some patients will develop radioresistance (RR) and relapse. The underlying mechanisms remain poorly understood, and miRNAs might be key players in the acquisi
Externí odkaz:
https://doaj.org/article/0fc0b34f43f243738215274c3fef238f
Autor:
Ugo Hirigoyen, Coraly Guilbaud, Morgane Krejbich, Morgane Fouet, Judith Fresquet, Bastien Arnaud, Emmanuelle Com, Charles Pineau, Gwenann Cadiou, Julien Burlaud-Gaillard, Philippe Erbs, Delphine Fradin, Nathalie Labarrière, Jean-François Fonteneau, Tacien Petithomme, Nicolas Boisgerault
Publikováno v:
Molecular Therapy: Oncology, Vol 32, Iss 4, Pp 200887- (2024)
Extracellular vesicles (EVs) are mediators of intercellular communication in the tumor microenvironment. Tumor EVs are commonly associated with metastasis, immunosuppression or drug resistance. Viral infections usually increase EV secretion, but litt
Externí odkaz:
https://doaj.org/article/476ae58ab35d439fa36d12f1b6f5d08e
Autor:
Camille Chatelain, Laurine Berland, Marion Grard, Nicolas Jouand, Judith Fresquet, Joëlle Nader, Ugo Hirigoyen, Tacien Petithomme, Chantal Combredet, Elvire Pons-Tostivint, Delphine Fradin, Lucas Treps, Christophe Blanquart, Nicolas Boisgerault, Frédéric Tangy, Jean-François Fonteneau
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
Attenuated measles virus (MV) exerts its oncolytic activity in malignant pleural mesothelioma (MPM) cells that lack type-I interferon (IFN-I) production or responsiveness. However, other cells in the tumor microenvironment (TME), such as myeloid cell
Externí odkaz:
https://doaj.org/article/b3ba27ed694c4cdcb2a9450d7b9a6e6f
Autor:
Pauline Hulo, Sophie Deshayes, Judith Fresquet, Anne-Laure Chéné, Stéphanie Blandin, Nicolas Boisgerault, Jean-François Fonteneau, Lucas Treps, Marc G Denis, Jaafar Bennouna, Delphine Fradin, Elvire Pons-Tostivint, Christophe Blanquart
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-14 (2024)
Abstract Background Lung cancers represent the main cause of cancer related-death worldwide. Recently, immunotherapy alone or in combination with chemotherapy has deeply impacted the therapeutic care leading to an improved overall survival. However,
Externí odkaz:
https://doaj.org/article/f68caea1887141088437dadc9d5e46a0
Autor:
Robert M. Tighe, Anastasiya Birukova, Yuryi Malakhau, Yoshihiko Kobayashi, Aaron T. Vose, Vidya Chandramohan, Jaime M. Cyphert-Daly, R. Ian Cumming, Helene Fradin Kirshner, Purushothama R. Tata, Jennifer L. Ingram, Michael D. Gunn, Loretta G. Que, Yen-Rei A. Yu
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionEnvironmental exposures and experimental manipulations can alter the ontogenetic composition of tissue-resident macrophages. However, the impact of these alterations on subsequent immune responses, particularly in allergic airway diseases
Externí odkaz:
https://doaj.org/article/58d830a0b7af4c4690d268b1d113ef6f