Zobrazeno 1 - 10
of 691
pro vyhledávání: '"P. Foray"'
Autor:
Arianna Moiani, Gil Letort, Sabrina Lizot, Anne Chalumeau, Chloe Foray, Tristan Felix, Diane Le Clerre, Sonal Temburni-Blake, Patrick Hong, Sophie Leduc, Noemie Pinard, Alan Marechal, Eduardo Seclen, Alex Boyne, Louisa Mayer, Robert Hong, Sylvain Pulicani, Roman Galetto, Agnès Gouble, Marina Cavazzana, Alexandre Juillerat, Annarita Miccio, Aymeric Duclert, Philippe Duchateau, Julien Valton
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Sickle cell disease is a devastating blood disorder that originates from a single point mutation in the HBB gene coding for hemoglobin. Here, we develop a GMP-compatible TALEN-mediated gene editing process enabling efficient HBB correction v
Externí odkaz:
https://doaj.org/article/a5ed07ba92514c729d823ca1c6aa5120
Autor:
Renaud Felten, Jacques-Eric Gottenberg, Lucienne Chatenoud, Jean Sibilia, Pascal Schneider, Hélène Dumortier, Fanny Monneaux, Anne-Perrine Foray, Cindy Marquet, Coralie Pecquet, Fabrice Valette
Publikováno v:
RMD Open, Vol 10, Iss 3 (2024)
Introduction The therapeutic interest of targeting B-cell activating factor (BAFF) in Sjögren’s disease (SjD) can be suspected from the results of two phase II clinical trials but has not been evaluated in an animal model of the disease. We aimed
Externí odkaz:
https://doaj.org/article/aeb9ef5d2b054bd393c889c8f29c66a5
Autor:
Juliette Restier-Verlet, Mélanie L. Ferlazzo, Adeline Granzotto, Joëlle Al-Choboq, Camélia Bellemou, Maxime Estavoyer, Florentin Lecomte, Michel Bourguignon, Laurent Pujo-Menjouet, Nicolas Foray
Publikováno v:
Cells, Vol 13, Iss 20, p 1703 (2024)
Radiation impacting astronauts in their spacecraft come from a “bath” of high-energy rays (0.1–0.5 mGy per mission day) that reaches deep tissues like the heart and bones and a “stochastic rain” of low-energy particles from the shielding an
Externí odkaz:
https://doaj.org/article/c585ed05f6f7446786bab067939d326b
Autor:
Harriet N. A. Blankson, Rashidatu Fouad Kamara, Ivan Barilar, Sönke Andres, Ousman S. Conteh, Tobias Dallenga, Lynda Foray, Florian Maurer, Katharina Kranzer, Christian Utpatel, Stefan Niemann
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 3 (2024)
ABSTRACTMultidrug-resistant tuberculosis (MDR-TB) management has become a serious global health challenge. Understanding its epidemic determinants on the regional level is crucial for developing effective control measures. We used whole genome sequen
Externí odkaz:
https://doaj.org/article/7d35b4b059ec4eb18f7ec1956c571550
Autor:
Adeline Granzotto, Laura El Nachef, Juliette Restier-Verlet, Laurène Sonzogni, Joëlle Al-Choboq, Michel Bourguignon, Nicolas Foray
Publikováno v:
Biomolecules, Vol 14, Iss 6, p 703 (2024)
Immunofluorescence with antibodies against phosphorylated forms of H2AX (γH2AX) is revolutionizing our understanding of repair and signaling of DNA double-strand breaks (DSBs). Unfortunately, the pattern of γH2AX foci depends upon a number of param
Externí odkaz:
https://doaj.org/article/613e193e7b66449fa4574263dba7436e
Autor:
Juliette Dessemon, Olivia Perol, Cécile Chauvel, Hugo Noelle, Thomas Coudon, Lény Grassot, Nicolas Foray, Elodie Belladame, Jérôme Fayette, Françoise Fournie, Aurélie Swalduz, Eve-Marie Neidhart, Pierre Saintigny, Mayeul Tabutin, Maxime Boussageon, Frédéric Gomez, Virginie Avrillon, Maurice Perol, Barbara Charbotel, Béatrice Fervers
Publikováno v:
Frontiers in Public Health, Vol 11 (2024)
IntroductionResidential exposure is estimated to be responsible for nearly 10% of lung cancers in 2015 in France, making it the second leading cause, after tobacco. The Auvergne-Rhône-Alpes region, in the southwest of France, is particularly affecte
Externí odkaz:
https://doaj.org/article/59eed2ed0592472bacd7aa9539ba0b7b
Akademický článek
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Akademický článek
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Akademický článek
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Autor:
Joëlle Al-Choboq, Myriam Nehal, Laurène Sonzogni, Adeline Granzotto, Laura El Nachef, Juliette Restier-Verlet, Mira Maalouf, Elise Berthel, Bernard Aral, Nadège Corradini, Michel Bourguignon, Nicolas Foray
Publikováno v:
Radiation, Vol 3, Iss 1, Pp 21-38 (2023)
The Rothmund–Thomson syndrome (RTS) is a rare autosomal recessive disease associated with poikiloderma, telangiectasias, sun-sensitive rash, hair growth problems, juvenile cataracts and, for a subset of some RTS patients, a high risk of cancer, esp
Externí odkaz:
https://doaj.org/article/96d82157c20449a08115a11e96534e13