Mitochondrial DNA impact on joint damaged process in a conplastic mouse model after being surgically induced with osteoarthritis

Autor: Morena Scotece, Ignacio Rego-Pérez, Ana Victoria Lechuga-Vieco, Alberto Centeno Cortés, María Concepción Jiménez-Gómez, Purificación Filgueira-Fernández, Carlos Vaamonde-García, José Antonio Enríquez, Francisco J. Blanco

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)

Abstract It has been suggested that mitochondrial dysfunction and mtDNA variations may contribute to osteoarthritis (OA) pathogenesis. However, the causative link to support this claim is lacking. Here, we surgically-induced OA in conplastic mice in

Externí odkaz: https://doaj.org/article/b5574bd366dc4090abea5086ff794bf4

Mitochondrial DNA impact on joint damaged process in a conplastic mouse model after being surgically induced with osteoarthritis

Autor: M. Scotece, María Concepción Jiménez-Gómez, Ignacio Rego-Pérez, Carlos Vaamonde-García, Francisco J. Blanco, Ana Victoria Lechuga-Vieco, Alberto Centeno Cortés, José Antonio Enríquez, P. Filgueira-Fernández

Publikováno v: Scientific Reports
RUC. Repositorio da Universidade da Coruña
instname
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Repisalud
Instituto de Salud Carlos III (ISCIII)
RUC: Repositorio da Universidade da Coruña
Universidade da Coruña (UDC)

[Abstract] It has been suggested that mitochondrial dysfunction and mtDNA variations may contribute to osteoarthritis (OA) pathogenesis. However, the causative link to support this claim is lacking. Here, we surgically-induced OA in conplastic mice i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7504278fddd9e69c91dff7efa4ab424
https://hdl.handle.net/20.500.12105/13418

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Effect of balneotherapy in sulfurous water on an in vivo murine model of osteoarthritis

Autor: Rosa Meijide-Faílde, Elena Fernández-Burguera, Carlos Vaamonde-García, Á. Vela-Anero, Tamara Hermida-Gómez, N. Goyanes, P. Filgueira-Fernández, Francisco J. Blanco

Publikováno v: RUC: Repositorio da Universidade da Coruña
Universidade da Coruña (UDC)
RUC. Repositorio da Universidade da Coruña
Universitat Oberta de Catalunya (UOC)

[Abstract] Osteoarthritis (OA) is a chronic joint disease that results in progressive cartilage destruction and subsequently joint dysfunction. Growing evidence indicates beneficial impact of balneological interventions in OA; however, their mechanis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::008a0d7ebad0f4f4776e535d583810bd
https://pubmed.ncbi.nlm.nih.gov/31828429

FRI0505 CORRELATIONS BETWEEN CARTILAGE MOLECULAR COMPOSITION DETERMINED BY RAMAN SPECTROSCOPY AND MANKIN SCORE: IMPACT OF INTER AND INTRA-VARIABILITY

Autor: Pío González, N. Goyanes, Joana Magalhães, Francisco J. Blanco, Paula Casal-Beiroa, Vanesa Balboa-Barreiro, P. Filgueira-Fernández, Sonia Pértega

Publikováno v: Cartilage, synovium and bone.

Background Osteoarthritis (OA) is an incurable disease and methods for its early diagnosis are still an unmet clinical need. Raman spectroscopy (RS) presents potential as a diagnosis technique based on the detection of peaks that can be assigned to c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::75c486ea49f99648cd3690820c2a4694
https://doi.org/10.1136/annrheumdis-2019-eular.5972