Intraarticular Administration Effect of Hydrogen Sulfide on an In Vivo Rat Model of Osteoarthritis

Autor: Carlos Vaamonde-García, Elena F. Burguera, Ángela Vela-Anero, Tamara Hermida-Gómez, Purificación Filgueira-Fernández, Jennifer A. Fernández-Rodríguez, Rosa Meijide-Faílde, Francisco J. Blanco

Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 19, p 7421 (2020)

Osteoarthritis (OA) is the most common articular chronic disease. However, its current treatment is limited and mostly symptomatic. Hydrogen sulfide (H2S) is an endogenous gas with recognized physiological activities. The purpose here was to evaluate

Externí odkaz: https://doaj.org/article/7bfe3ccd17d54ce3aca572dd336da76b

Mitochondrial DNA impact on joint damaged process in a conplastic mouse model after being surgically induced with osteoarthritis

Autor: M. Scotece, María Concepción Jiménez-Gómez, Ignacio Rego-Pérez, Carlos Vaamonde-García, Francisco J. Blanco, Ana Victoria Lechuga-Vieco, Alberto Centeno Cortés, José Antonio Enríquez, P. Filgueira-Fernández

Publikováno v: Scientific Reports
RUC. Repositorio da Universidade da Coruña
instname
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Repisalud
Instituto de Salud Carlos III (ISCIII)
RUC: Repositorio da Universidade da Coruña
Universidade da Coruña (UDC)

[Abstract] It has been suggested that mitochondrial dysfunction and mtDNA variations may contribute to osteoarthritis (OA) pathogenesis. However, the causative link to support this claim is lacking. Here, we surgically-induced OA in conplastic mice i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7504278fddd9e69c91dff7efa4ab424
https://hdl.handle.net/20.500.12105/13418

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Effect of balneotherapy in sulfurous water on an in vivo murine model of osteoarthritis

Autor: Rosa Meijide-Faílde, Elena Fernández-Burguera, Carlos Vaamonde-García, Á. Vela-Anero, Tamara Hermida-Gómez, N. Goyanes, P. Filgueira-Fernández, Francisco J. Blanco

Publikováno v: RUC: Repositorio da Universidade da Coruña
Universidade da Coruña (UDC)
RUC. Repositorio da Universidade da Coruña
Universitat Oberta de Catalunya (UOC)

[Abstract] Osteoarthritis (OA) is a chronic joint disease that results in progressive cartilage destruction and subsequently joint dysfunction. Growing evidence indicates beneficial impact of balneological interventions in OA; however, their mechanis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::008a0d7ebad0f4f4776e535d583810bd
https://pubmed.ncbi.nlm.nih.gov/31828429

FRI0505 CORRELATIONS BETWEEN CARTILAGE MOLECULAR COMPOSITION DETERMINED BY RAMAN SPECTROSCOPY AND MANKIN SCORE: IMPACT OF INTER AND INTRA-VARIABILITY

Autor: Pío González, N. Goyanes, Joana Magalhães, Francisco J. Blanco, Paula Casal-Beiroa, Vanesa Balboa-Barreiro, P. Filgueira-Fernández, Sonia Pértega

Publikováno v: Cartilage, synovium and bone.

Background Osteoarthritis (OA) is an incurable disease and methods for its early diagnosis are still an unmet clinical need. Raman spectroscopy (RS) presents potential as a diagnosis technique based on the detection of peaks that can be assigned to c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::75c486ea49f99648cd3690820c2a4694
https://doi.org/10.1136/annrheumdis-2019-eular.5972