Zobrazeno 1 - 10
of 54
pro vyhledávání: '"P. F. Richter"'
Publikováno v:
HardwareX, Vol 20, Iss , Pp e00581- (2024)
The implementation of automation has already had a considerable impact on chemical and pharmaceutical industrial laboratories. However, academic laboratories have often been more reluctant to adopt such technology due to the high cost of commercial l
Externí odkaz:
https://doaj.org/article/fa33bf41c8b144c3a28ecbcf26f5fd94
Publikováno v:
Materials Today Bio, Vol 25, Iss , Pp 101006- (2024)
Bone remodelling, important for homeostasis and regeneration involves the controlled action of osteoblasts, osteocytes and osteoclasts. The present study established a three-dimensional human in vitro bone model as triple culture with simultaneously
Externí odkaz:
https://doaj.org/article/6d224ab5c4f242e5a8b790d7f8d2650d
Publikováno v:
Results in Chemistry, Vol 7, Iss , Pp 101421- (2024)
Two chiral imidazolium salts and one chiral triazolium salt were synthesized containing a chiral cyclohexane bridge based on the salen ligand framework of the Jacobsen-Katsuki epoxidation catalysts. They are promising NHC and aNHC ligand precursors f
Externí odkaz:
https://doaj.org/article/5959dca796cd4fc88d81f2164d8c25a0
Autor:
Jakob C. Stüber, Karin F. Rechberger, Saša M. Miladinović, Thomas Pöschinger, Tamara Zimmermann, Remi Villenave, Miro J. Eigenmann, Thomas E. Kraft, Dhaval K. Shah, Hubert Kettenberger, Wolfgang F. Richter
Publikováno v:
AAPS Open, Vol 8, Iss 1, Pp 1-18 (2022)
Abstract This study explores the impact of antibody surface charge on tissue distribution into various tissues including tumor. Tumor-bearing mice were dosed intravenously with a mixture comprising three antibodies engineered to carry negative charge
Externí odkaz:
https://doaj.org/article/7356f1aec7b84b8489b40eb563178c52
Autor:
Karelle Ménochet, Hongbin Yu, Bonnie Wang, Jay Tibbitts, Cheng-Pang Hsu, Amrita V. Kamath, Wolfgang F. Richter, Andreas Baumann
Publikováno v:
mAbs, Vol 14, Iss 1 (2022)
Monoclonal antibodies (mAbs) deliver great benefits to patients with chronic and/or severe diseases thanks to their strong specificity to the therapeutic target. As a result of this specificity, non-human primates (NHP) are often the only preclinical
Externí odkaz:
https://doaj.org/article/0dd48640109d457fb44fab13cc929494
Autor:
Christoph F. Richter, Christopher J. Lortie, Tamara L. Kelly, Alessandro Filazzola, Krystal A. Nunes, Raani Sarkar
Publikováno v:
Ecology and Evolution, Vol 11, Iss 8, Pp 3616-3624 (2021)
Abstract Teaching ecology effectively and experientially has become more challenging for at least two reasons today. Most experiences of our students are urban, and we now face the near immediate and continuing need to deliver courses (either partial
Externí odkaz:
https://doaj.org/article/8331f41e5fe348dcbb7e008a958e9909
Publikováno v:
Atmospheric Measurement Techniques, Vol 14, Pp 1561-1571 (2021)
Wide-field spectrometers for Earth observation missions require in-flight radiometric calibration for which the Sun can be used as a known reference. Therefore, a diffuser is placed in front of the spectrometer in order to scatter the incoming light
Externí odkaz:
https://doaj.org/article/244c0f27c952443e8be3bec69436b854
Autor:
Martina Geiger, Kay-Gunnar Stubenrauch, Johannes Sam, Wolfgang F. Richter, Gregor Jordan, Jan Eckmann, Carina Hage, Valeria Nicolini, Anne Freimoser-Grundschober, Mirko Ritter, Matthias E. Lauer, Henning Stahlberg, Philippe Ringler, Jigar Patel, Eric Sullivan, Sandra Grau-Richards, Stefan Endres, Sebastian Kobold, Pablo Umaña, Peter Brünker, Christian Klein
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
The clinical application of T cell bispecific antibodies (TCBs) is often limited by the lack of tumour-specific antigens. In this study, the authors present a strategy to increase TCB tumour-selectivity by adding an anti-CD3 moiety that can be specif
Externí odkaz:
https://doaj.org/article/8ea92b14dd394c6fac60d2c9ad4feca4
Publikováno v:
eLife, Vol 10 (2021)
MLL-rearranged leukemia depends on H3K79 methylation. Depletion of this transcriptionally activating mark by DOT1L deletion or high concentrations of the inhibitor pinometostat downregulates HOXA9 and MEIS1, and consequently reduces leukemia survival
Externí odkaz:
https://doaj.org/article/e5b40cfc226c4f88af0da6f8ae7c2097
Autor:
Deborah Delbue, Lydia Lebenheim, Danielle Cardoso-Silva, Violaine Dony, Susanne M. Krug, Jan F. Richter, Subhakankha Manna, Melba Muñoz, Kerstin Wolk, Claudia Heldt, Markus M. Heimesaat, Robert Sabat, Britta Siegmund, Michael Schumann
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Background: Interleukin-22 (IL-22) impacts the integrity of intestinal epithelia and has been associated with the development of colitis-associated cancer and inflammatory bowel diseases (IBD). Previous data suggest that IL-22 protects the mucosal ba
Externí odkaz:
https://doaj.org/article/113c05147356492e9a76707d9906f783