Zobrazeno 1 - 10
of 27
pro vyhledávání: '"P. F. McDonagh"'
Autor:
Daniel C Kirouac, Jinyan Du, Johanna Lahdenranta, Matthew D Onsum, Ulrik B Nielsen, Birgit Schoeberl, Charlotte F McDonagh
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 4, p e1004827 (2016)
Understanding the molecular pathways by which oncogenes drive cancerous cell growth, and how dependence on such pathways varies between tumors could be highly valuable for the design of anti-cancer treatment strategies. In this work we study how depe
Externí odkaz:
https://doaj.org/article/31a32c2b6edf4eab836911f6779157c6
Publikováno v:
Journal of Lipid Research, Vol 38, Iss 6, Pp 1178-1188 (1997)
pKas for the acid dissociation of the carboxyl groups of bilirubin in water have been reported recently to be 8.1-8.4, or higher. These high values were attributed to intramolecular hydrogen bonding. They have led to suggestions that monoanions of bi
Externí odkaz:
https://doaj.org/article/4e121a3fc9444ddaade8be8288f6dd1c
Autor:
Hussein N. Yassine, Grace Davis-Gorman, Craig S. Stump, Stephen S. Thomson, Justin Peterson, Paul F. McDonagh
Publikováno v:
International Journal of Endocrinology, Vol 2010 (2010)
Aspirin has lower antiplatelet activity in diabetic patients. Our aim is to study the roles of acute hyperglycemia and hyperlipidemia on aspirin function in diabetic subjects with and without cardiovascular disease. Using urine thromboxane (pg/mg cre
Externí odkaz:
https://doaj.org/article/1e3c0e50136247b89c2c808d45c7d81a
Publikováno v:
Stroke. 31:1153-1161
Background and Purpose —Leukocytes contribute to cerebral ischemia-reperfusion injury. However, few experimental models examine both in vivo behavior of leukocytes and microvascular rheology after stroke. The purpose of the present study was to cha
Publikováno v:
Diabetes. 46:1859-1867
Autor:
P. F Mcdonagh, J. M Reynolds
Publikováno v:
Cardiovascular Research. 28:1156-1165
Autor:
J. M. Reynolds, P. F. McDonagh
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 266:H171-H181
Several studies indicate that leukocytes and platelets exacerbate the compromise of myocardial function that occurs after ischemia-reperfusion (I/R). However, it is unclear whether both leukocytes and platelets must be present to mediate coronary mic
Autor:
P F, McDonagh, J Y, Hokama
Publikováno v:
Microcirculation (New York, N.Y. : 1994). 7(3)
Diabetes is a chronic disease of metabolic dysfunction that is increasing world-wide. The hyperglycemia associated with diabetes causes significant protein alterations and an oxidative stress. In the heart, all cell types are affected by diabetes: th
Publikováno v:
International journal of microcirculation, clinical and experimental. 12(1)
In order to further elucidate the possible contribution of leukocytes to microvascular injury during reperfusion following total hepatic ischemia, we studied the spatial relationship between areas of white cell accumulation and areas of microvascular