Zobrazeno 1 - 10
of 88
pro vyhledávání: '"P. F. Fleming"'
Autor:
R. A. Hutchinson, K. L. Costeloe, W. G. Wade, M. R. Millar, K. Ansbro, F. Stacey, P. F. Fleming
Publikováno v:
Gut Pathogens, Vol 15, Iss 1, Pp 1-13 (2023)
Abstract Background Intestinal dysbiosis is implicated in the origins of necrotising enterocolitis and late-onset sepsis in preterm babies. However, the effect of modulators of bacterial growth (e.g. antibiotics) upon the developing microbiome is not
Externí odkaz:
https://doaj.org/article/a6ef950d2042419bbede90a5f1979915
Autor:
Bilal Altundas, Embarek Alwedi, Zhihui Song, Achyut Ranjan Gogoi, Ryan Dykstra, Osvaldo Gutierrez, Fraser F. Fleming
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-8 (2022)
As aromatic compounds can be obtained easily, their functionalization is a cornerstone of organic synthesis. Here, the authors report a dearomatization of aromatic isocyanides, installing three carbon-carbon bonds, two quaternary stereocenters, and t
Externí odkaz:
https://doaj.org/article/ff975ccea194463b99bafab97f8fb823
Autor:
Minhaz Ur Rahman, Derek F. Fleming, Liyun Wang, Kendra P. Rumbaugh, Vernita D. Gordon, Gordon F. Christopher
Publikováno v:
npj Biofilms and Microbiomes, Vol 8, Iss 1, Pp 1-9 (2022)
Abstract A new technique was used to measure the viscoelasticity of in vivo Pseudomonas aeruginosa biofilms. This was done through ex vivo microrheology measurements of in vivo biofilms excised from mouse wound beds. To our knowledge, this is the fir
Externí odkaz:
https://doaj.org/article/1d996939d5684c32974825dcb41cd99f
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 17, Iss 1, Pp 1499-1502 (2021)
Substituted imidazoles are readily prepared by condensing the versatile isocyanide Asmic, anisylsulfanylmethylisocyanide, with nitrogenous π-electrophiles. Deprotonating Asmic with lithium hexamethyldisilazide effectively generates a potent nucleoph
Externí odkaz:
https://doaj.org/article/40483b1c5e124c75ade00ec2e5a93ef6
Autor:
Katherine C. Kurnit, Meghan Steiner, Ricardo R. Lastra, S. John Weroha, John Cursio, Ernst Lengyel, Gini F. Fleming, Suzanne D. Conzen
Publikováno v:
Gynecologic Oncology Reports, Vol 41, Iss , Pp 100987- (2022)
Glucocorticoid receptor can be associated with poor prognosis among a variety of solid tumors in the absence of other nuclear hormone receptors. Our objective was to characterize differences in glucocorticoid receptor (GR), estrogen receptor (ER), pr
Externí odkaz:
https://doaj.org/article/74f001dec45142a8b94f7bb8d13439d0
Publikováno v:
ACS Omega, Vol 5, Iss 22, Pp 13384-13388 (2020)
Externí odkaz:
https://doaj.org/article/0c550af31a3b4e31b5425db150fb0d66
Autor:
John Wright, Stephanie Lheureux, Ilaria Colombo, Ramy Gadalla, Pamela S Ohashi, Xuan Li, Lisa Wang, Matthew S Block, David G Brooks, Andrea Jewell, Carolyn McCourt, Eugenia Girda, Sarah Temkin, Gini F Fleming, Linda Duska, Daniela E Matei, Panagiotis A Konstantinopoulos, Ben X Wang, Stephanie L Gaillard, Michael McHale, Floor J Backes, Theresa L Werner, Siobhan Kehoe, Rachel Wildman, Shirin Soleimani, Scott Lien, Trevor Pugh
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 3 (2022)
Background Combining immunotherapy and antiangiogenic agents is a promising treatment strategy in endometrial cancer. To date, no biomarkers for response have been identified and data on post-immunotherapy progression are lacking. We explored the com
Externí odkaz:
https://doaj.org/article/0e5bfe1cd7414e458e3cfe2d6fbf3f50
Autor:
Anase S. Asom, Ricardo R. Lastra, Yasmin Hasan, Lori Weinberg, Gini F. Fleming, Katherine C. Kurnit
Publikováno v:
Gynecologic Oncology Reports, Vol 39, Iss , Pp 100925- (2022)
Background: Primary small cell ovarian cancer of pulmonary type (SCCOPT) remains a rare ovarian tumor. Its aggressive nature is associated with poor survival outcomes. Current treatment algorithms rely on systemic chemotherapy, primarily involving pl
Externí odkaz:
https://doaj.org/article/a8fa42dd1a3a4a5f8c8818ebdc6e8ef9
Publikováno v:
Gynecologic Oncology Reports, Vol 37, Iss , Pp 100837- (2021)
Externí odkaz:
https://doaj.org/article/fd44395771e740a3a35fb12fb91788a8
Autor:
Eva Tonsing-Carter, Kyle M. Hernandez, Caroline R. Kim, Ryan V. Harkless, Alyce Oh, Kathleen R. Bowie, Diana C. West-Szymanski, Mayra A. Betancourt-Ponce, Bradley D. Green, Ricardo R. Lastra, Gini F. Fleming, Sarat Chandarlapaty, Suzanne D. Conzen
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-15 (2019)
Abstract Background Non-ER nuclear receptor activity can alter estrogen receptor (ER) chromatin association and resultant ER-mediated transcription. Consistent with GR modulation of ER activity, high tumor glucocorticoid receptor (GR) expression corr
Externí odkaz:
https://doaj.org/article/15ee561df07048839912c4364c12edf6