Zobrazeno 1 - 10
of 13
pro vyhledávání: '"P. F. DOWNIE"'
Publikováno v:
Clinical Science. 102:9-14
The glycoprotein 130 (gp130) signalling pathway is important in the development of heart failure. Cardiotrophin-1 (CT-1), a cytokine acting via the gp130 pathway, is involved in the process of ventricular remodelling following acute myocardial infarc
Publikováno v:
Metabolism. 50:237-240
Cardiotrophin-1 (CT-1) is a recently identified cytokine of the interleukin-6 (IL-6) family that signals through the gp130 signalling pathway. CT-1 may be of central importance to the pathogenesis of ventricular remodelling in patients with acute myo
Publikováno v:
European Journal of Heart Failure. 3:15-19
Background: Echocardiography with Doppler examination of the aortic valve provides a very accurate assessment of the transvalvular gradient and is used to monitor progression of aortic stenosis (AS). Plasma brain natriuretic peptide (BNP) has been sh
Publikováno v:
Heart. 84:421-424
OBJECTIVE—To compare circulating concentrations of N terminal pro-brain natriuretic peptide (N-BNP) and cardiotrophin 1 in stable and unstable angina. DESIGN AND SETTING—Observational study in a teaching hospital. PATIENTS—15 patients with unst
Autor:
S Talwar, M C Campton, A M Mccullough, Leong L. Ng, David B. Barnett, Joan E. Davies, P. F. Downie, Iain B. Squire
Publikováno v:
European Heart Journal. 21:1514-1521
Aims The aims of this study were to describe the temporal pattern of plasma N-terminal pro-brain natriuretic peptide, to examine the optimum time of sampling and to compare plasma N-terminal pro-brain natriuretic peptide to clinical criteria in terms
Publikováno v:
British Journal of Clinical Pharmacology. 50:15-20
Heart failure is one of the most common conditions of industrialized society and at its most florid encompasses a constellation of symptoms and signs associated with demonstrable left ventricular systolic dysfunction (LVSD) [1]. Many patients with cl
Publikováno v:
Clinical Science. 99:83-88
Cardiotrophin-1 (CT-1) is a cytokine that has been implicated as a factor involved in myocardial remodelling. The objective of the present study was to establish the relationship between circulating levels of CT-1 and measures of left ventricular siz
Publikováno v:
Biochemical and Biophysical Research Communications. 261:567-571
Cardiotrophin-1, a member of the interleukin-6 related cytokine family which acts via the glycoprotein 130 signalling pathway, may be involved in the process of ventricular remodelling. Its presence in human plasma has never been reported. We have de
Publikováno v:
Clinical science (London, England : 1979). 97(3)
Plasma concentrations of N-terminal pro-brain natriuretic peptide (NT-proBNP) are raised in patients with left ventricular dysfunction. Measurement of this peptide has a potential diagnostic role in the identification and assessment of patients with
Publikováno v:
Clinical Science. 99:83
Cardiotrophin-1 (CT-1) is a cytokine that has been implicated as a factor involved in myocardial remodelling. The objective of the present study was to establish the relationship between circulating levels of CT-1 and measures of left ventricular siz