Zobrazeno 1 - 10
of 30
pro vyhledávání: '"P. F. Carey"'
Autor:
Michael Kronenberg, Michael F. Carey
Publikováno v:
iScience, Vol 26, Iss 1, Pp 105791- (2023)
Summary: Head-on (HO) collisions between the DNA replication machinery and RNA polymerase over R-loop forming sequences (RLFS) are genotoxic, leading to replication fork blockage and DNA breaks. Current models suggest that HO collisions are avoided t
Externí odkaz:
https://doaj.org/article/3aa6a83675924036a610f49fab6b71c7
Autor:
Allison F. Carey, Xin Wang, Nico Cicchetti, Caitlin N. Spaulding, Qingyun Liu, Forrest Hopkins, Jessica Brown, Jaimie Sixsmith, Rujapak Sutiwisesak, Samuel M. Behar, Thomas R. Ioerger, Sarah M. Fortune
Publikováno v:
mSystems, Vol 7, Iss 3 (2022)
ABSTRACT There is growing evidence that genetic diversity in Mycobacterium tuberculosis, the causative agent of tuberculosis, contributes to the outcomes of infection and public health interventions, such as vaccination. Epidemiological studies sugge
Externí odkaz:
https://doaj.org/article/13c144ed64584ffa9e4d276cd663ac62
Autor:
Qikun Liu, Sylvain Bischof, C. Jake Harris, Zhenhui Zhong, Lingyu Zhan, Calvin Nguyen, Andrew Rashoff, William D. Barshop, Fei Sun, Suhua Feng, Magdalena Potok, Javier Gallego-Bartolome, Jixian Zhai, James A. Wohlschlegel, Michael F. Carey, Jeffrey A. Long, Steven E. Jacobsen
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Mediator is a multiprotein complex required to activate gene transcription by RNAPII. Here, the authors report that MED12 and MED13 are conditional positive regulators that facilitate the expression of genes depleted in active chromatin marks and the
Externí odkaz:
https://doaj.org/article/a1f7481a95074346be1780a4740809f3
Autor:
Henry F. Carey
Publikováno v:
Utrecht Law Review, Vol 16, Iss 2 (2020)
The Special Rapporteur for Safe Drinking Water and Sanitation is a norm entrepreneur, both as a norm monitor and clarifier, as well as an advocate for reparative action for victims. Two incumbents have identified fundamental principles of these two h
Externí odkaz:
https://doaj.org/article/b463bf4c22004c1fb52d6e0c5652f011
Autor:
Allison F Carey, Jeremy M Rock, Inna V Krieger, Michael R Chase, Marta Fernandez-Suarez, Sebastien Gagneux, James C Sacchettini, Thomas R Ioerger, Sarah M Fortune
Publikováno v:
PLoS Pathogens, Vol 15, Iss 6, p e1007846 (2019)
[This corrects the article DOI: 10.1371/journal.ppat.1006939.].
Externí odkaz:
https://doaj.org/article/2c2ac25370d24c27a9c8f1908b1fb20a
Publikováno v:
mBio, Vol 10, Iss 2 (2019)
ABSTRACT In Mycobacterium tuberculosis, recent genome-wide association studies have identified a novel constellation of mutations that are correlated with high-level drug resistances. Interpreting the functional importance of the new resistance-assoc
Externí odkaz:
https://doaj.org/article/f930b5b630724c45a84da918597a5194
Autor:
Anthony M Cadena, Forrest F Hopkins, Pauline Maiello, Allison F Carey, Eileen A Wong, Constance J Martin, Hannah P Gideon, Robert M DiFazio, Peter Andersen, Philana Ling Lin, Sarah M Fortune, JoAnne L Flynn
Publikováno v:
PLoS Pathogens, Vol 14, Iss 10, p e1007305 (2018)
For many pathogens, including most targets of effective vaccines, infection elicits an immune response that confers significant protection against reinfection. There has been significant debate as to whether natural Mycobacterium tuberculosis (Mtb) i
Externí odkaz:
https://doaj.org/article/ad202065f80e48eeae2994517ddee81a
Autor:
Allison F Carey, Jeremy M Rock, Inna V Krieger, Michael R Chase, Marta Fernandez-Suarez, Sebastien Gagneux, James C Sacchettini, Thomas R Ioerger, Sarah M Fortune
Publikováno v:
PLoS Pathogens, Vol 14, Iss 3, p e1006939 (2018)
Once considered a phenotypically monomorphic bacterium, there is a growing body of work demonstrating heterogeneity among Mycobacterium tuberculosis (Mtb) strains in clinically relevant characteristics, including virulence and response to antibiotics
Externí odkaz:
https://doaj.org/article/368fa7027058421bb8b1ce8c90c02fb1
Autor:
Prabha Shrestha, David A Davis, Ravindra P Veeranna, Robert F Carey, Coralie Viollet, Robert Yarchoan
Publikováno v:
PLoS Pathogens, Vol 13, Iss 9, p e1006628 (2017)
Primary effusion lymphoma (PEL) is an aggressive B-cell lymphoma with poor prognosis caused by Kaposi's sarcoma-associated herpesvirus (KSHV). Previous studies have revealed that HIF-1α, which mediates much of the cellular response to hypoxia, plays
Externí odkaz:
https://doaj.org/article/ebff82954f8c46b2a5ef30bf7800501b
Autor:
David A Davis, Nicole E Naiman, Victoria Wang, Prabha Shrestha, Muzammel Haque, Duosha Hu, Holda A Anagho, Robert F Carey, Katharine S Davidoff, Robert Yarchoan
Publikováno v:
PLoS Pathogens, Vol 11, Iss 7, p e1005064 (2015)
Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus-8, is the causative agent of three hyperproliferative disorders: Kaposi's sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman's disease. During viral late
Externí odkaz:
https://doaj.org/article/d6c410bf28204d7a844e0f158cf3ed42