Zobrazeno 1 - 10
of 37
pro vyhledávání: '"P. F. Billingsley"'
Autor:
Patricia Ferrer, Andrea A. Berry, Allison N. Bucsan, Surendra K. Prajapati, Karthik Krishnan, Michelle C. Barbeau, David M. Rickert, Sandra Mendoza Guerrero, Miho Usui, Yonas Abebe, Asha Patil, Sumana Chakravarty, Peter F. Billingsley, Faith Pa’ahana-Brown, Kathy Strauss, Biraj Shrestha, Effie Nomicos, Gregory A. Deye, B. Kim Lee Sim, Stephen L. Hoffman, Kim C. Williamson, Kirsten E. Lyke
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Resistance to clinical malaria takes years to develop even in hyperendemic regions and sterilizing immunity has rarely been observed. To evaluate the maturation of the host response against controlled repeat exposures to P. falciparum (Pf) N
Externí odkaz:
https://doaj.org/article/7a3ddfce59954bb4905f2bfc862aaeeb
Autor:
Anneth Tumbo, Freia-Raphaella Lorenz, Annie S.P. Yang, Stephanie Sefried, Tobias Schindler, Maximilian Mpina, Jean-Pierre Dangy, Florence A. Milando, Mohammed A. Rashid, Gloria Nyaulingo, Kamaka Ramadhani, Said Jongo, Philip L. Felgner, Yonas Abebe, B. Kim Lee Sim, L.W. Preston Church, Thomas L. Richie, Peter F. Billingsley, Tooba Murshedkar, Stephen L. Hoffman, Salim Abdulla, Peter G. Kremsner, Benjamin Mordmüller, Claudia Daubenberger, Rolf Fendel
Publikováno v:
EBioMedicine, Vol 108, Iss , Pp 105364- (2024)
Summary: Background: PfSPZ Vaccine, a promising pre-erythrocytic stage malaria vaccine candidate based on whole, radiation-attenuated Plasmodium falciparum (Pf) sporozoites (SPZ), has proven safe and effective in mediating sterile protection from mal
Externí odkaz:
https://doaj.org/article/608a577a935848f082781131f68893d7
Autor:
Leila Kianifard, Ab. Matteen Rafiqi, Osman Akcakir, Ahmed S. I. Aly, Peter F. Billingsley, Serdar Uysal
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract The control of malaria parasite transmission from mosquitoes to humans is hampered by decreasing efficacies of insecticides, development of drug resistance against the last-resort antimalarials, and the absence of effective vaccines. Herein,
Externí odkaz:
https://doaj.org/article/1534aaddcdb448de98cf1a1e30b61c83
Autor:
Thomas L. Richie, L.W. Preston Church, Tooba Murshedkar, Peter F. Billingsley, Eric R. James, Mei-Chun Chen, Yonas Abebe, Natasha KC, Sumana Chakravarty, David Dolberg, Sara A. Healy, Halimatou Diawara, Mahamadou S. Sissoko, Issaka Sagara, David M. Cook, Judith E. Epstein, Benjamin Mordmüller, Melissa Kapulu, Andrea Kreidenweiss, Blandine Franke-Fayard, Selidji T. Agnandji, María-Silvia A. López Mikue, Matthew B.B. McCall, Laura Steinhardt, Martina Oneko, Ally Olotu, Ashley M. Vaughan, James G. Kublin, Sean C. Murphy, Said Jongo, Marcel Tanner, Sodiomon B. Sirima, Matthew B. Laurens, Claudia Daubenberger, Joana C. Silva, Kirsten E. Lyke, Chris J. Janse, Meta Roestenberg, Robert W. Sauerwein, Salim Abdulla, Alassane Dicko, Stefan H. I. Kappe, B. Kim Lee Sim, Patrick E. Duffy, Peter G. Kremsner, Stephen L. Hoffman
Publikováno v:
Expert Review of Vaccines, Vol 0, Iss 0 (2023)
Introduction Malaria, a devastating febrile illness caused by protozoan parasites, sickened 247,000,000 people in 2021 and killed 619,000, mostly children and pregnant women in sub-Saharan Africa. A highly effective vaccine is urgently needed, especi
Externí odkaz:
https://doaj.org/article/64ccc130995e4fbda0570808ef7ca47d
Autor:
Benjamin Mordmüller, Zita Sulyok, Mihály Sulyok, Zsofia Molnar, Albert Lalremruata, Carlos Lamsfus Calle, Patricia Granados Bayon, Meral Esen, Markus Gmeiner, Jana Held, Henri-Lynn Heimann, Tamirat Gebru Woldearegai, Javier Ibáñez, Judith Flügge, Rolf Fendel, Andrea Kreidenweiss, Natasha KC, Tooba Murshedkar, Sumana Chakravarty, Pouria Riyahi, Peter F. Billingsley, L. W. Preston Church, Thomas L. Richie, B. Kim Lee Sim, Stephen L. Hoffman, Peter G. Kremsner
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-9 (2022)
Abstract Immunization with radiation-attenuated Plasmodium falciparum (Pf) sporozoites (SPZ) in PfSPZ Vaccine, has provided better vaccine efficacy (VE) against controlled human malaria infection (CHMI) with the same parasites as in the vaccine (homo
Externí odkaz:
https://doaj.org/article/14917a5ef92d4531811eec64c343ca82
Autor:
Maxmillian Mpina, Thomas C. Stabler, Tobias Schindler, Jose Raso, Anna Deal, Ludmila Acuche Pupu, Elizabeth Nyakarungu, Maria del Carmen Ovono Davis, Vicente Urbano, Ali Mtoro, Ali Hamad, Maria Silvia A. Lopez, Beltran Pasialo, Marta Alene Owono Eyang, Matilde Riloha Rivas, Carlos Cortes Falla, Guillermo A. García, Juan Carlos Momo, Raul Chuquiyauri, Elizabeth Saverino, L. W. Preston Church, B. Kim lee Sim, Bonifacio Manguire, Marcel Tanner, Carl Maas, Salim Abdulla, Peter F. Billingsley, Stephen L. Hoffman, Said Jongo, Thomas L. Richie, Claudia A. Daubenberger
Publikováno v:
Malaria Journal, Vol 21, Iss 1, Pp 1-14 (2022)
Abstract Background Progress towards malaria elimination has stagnated, partly because infections persisting at low parasite densities comprise a large reservoir contributing to ongoing malaria transmission and are difficult to detect. This study com
Externí odkaz:
https://doaj.org/article/afc3035edca147288642779878104b0a
Autor:
Eric R. James, Yingda Wen, James Overby, Kristen Pluchino, Shane McTighe, Stephen Matheny, Abraham Eappen, Stephen L. Hoffman, Peter F. Billingsley
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-6 (2022)
Abstract The ability to cryopreserve mosquitoes would revolutionize work on these vectors of major human infectious diseases by conserving stocks, new isolates, lab-bred strains, and transgenic lines that currently require continuous life cycle maint
Externí odkaz:
https://doaj.org/article/e3de1a79dabc4ce6903ee65ecf464176
Autor:
Natasha KC, L. W. Preston Church, Pouria Riyahi, Sumana Chakravarty, Robert A. Seder, Judith E. Epstein, Kirsten E. Lyke, Benjamin Mordmüller, Peter G. Kremsner, Mahamadou S. Sissoko, Sara Healy, Patrick E. Duffy, Said A. Jongo, Vicente Urbano Nsue Ndong Nchama, Salim Abdulla, Maxmillian Mpina, Sodiomon B. Sirima, Matthew B. Laurens, Laura C. Steinhardt, Martina Oneko, MingLin Li, Tooba Murshedkar, Peter F. Billingsley, B. Kim Lee Sim, Thomas L. Richie, Stephen L. Hoffman
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundWhile prior research has shown differences in the risk of malaria infection and sickness between males and females, little is known about sex differences in vaccine-induced immunity to malaria. Identifying such differences could elucidate i
Externí odkaz:
https://doaj.org/article/d6334f1741f1482b91e5bb9239e66e76
Autor:
Vicente Urbano Nsue Ndong Nchama, Ali Hamad Said, Ali Mtoro, Gertrudis Owono Bidjimi, Marta Alene Owono, Escolastica Raquel Mansogo Maye, Martin Eka Ondo Mangue, Genaro Nsue Nguema Okomo, Beltran Ekua Ntutumu Pasialo, Dolores Mbang Ondo, Maria-Silvia Angue Lopez, Fortunata Lobede Mochomuemue, Mariano Obiang Obono, Juan Carlos Momo Besaha, Raul Chuquiyauri, Said Abdallah Jongo, Kassim Kamaka, Ummi Abdul Kibondo, Thabit Athuman, Carlos Cortez Falla, Jeremías Nzamio Mba Eyono, Jordan Michael Smith, Guillermo A. García, José Raso, Elizabeth Nyakarungu, Maxmillian Mpina, Tobias Schindler, Claudia Daubenberger, Laurence Lemiale, Peter F. Billingsley, B. Kim Lee Sim, Thomas L. Richie, L. W. Preston Church, Ally Olotu, Marcel Tanner, Stephen L. Hoffman, Salim Abdulla
Publikováno v:
Malaria Journal, Vol 20, Iss 1, Pp 1-13 (2021)
Abstract Background Extensive malaria control measures have been implemented on Bioko Island, Equatorial Guinea over the past 16 years, reducing parasite prevalence and malaria-related morbidity and mortality, but without achieving elimination. Malar
Externí odkaz:
https://doaj.org/article/3e7774f81b3642fb8979372514e81536
Autor:
Peter F. Billingsley, Kasim I. George, Abraham G. Eappen, Robert A. Harrell, Robert Alford, Tao Li, Sumana Chakravarty, B. Kim Lee Sim, Stephen L. Hoffman, David A. O’Brochta
Publikováno v:
Malaria Journal, Vol 20, Iss 1, Pp 1-12 (2021)
Abstract Background Plasmodium falciparum (Pf) sporozoites (PfSPZ) can be administered as a highly protective vaccine conferring the highest protection seen to date. Sanaria® PfSPZ vaccines are produced using aseptically reared Anopheles stephensi m
Externí odkaz:
https://doaj.org/article/e171d514987a4065ad10996b149acd97