Zobrazeno 1 - 10
of 302
pro vyhledávání: '"P. E. Squires"'
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-23 (2024)
Abstract Background Accompanied by activation of the NOD-like receptor protein 3 (NLRP3) inflammasome, aberrant connexin 43 (Cx43) hemichannel-mediated ATP release is situated upstream of inflammasome assembly and inflammation and contributes to mult
Externí odkaz:
https://doaj.org/article/9baaa553b8e54c52af7f74891fbd3783
Publikováno v:
Frontiers in Systems Biology, Vol 4 (2024)
IntroductionPediatric Acute Liver Failure (PALF) presents as a rapidly evolving, multifaceted, and devastating clinical syndrome whose precise etiology remains incompletely understood. Consequently, predicting outcomes—whether survival or mortality
Externí odkaz:
https://doaj.org/article/3e1bb658158247bc9329dacfd2e15c34
Autor:
Lauren Orser, Janet E. Squires, Alexandra Musten, Nikki Ho, Jennifer Lindsay, Nitika Pant Pai, Patrick O’Byrne
Publikováno v:
BMC Public Health, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background In Ontario, Canada we developed and implemented an online screening algorithm for the distribution of HIV self-tests, known as GetaKit. During the COVID pandemic, we adapted the GetaKit algorithm to screen for COVID based on popul
Externí odkaz:
https://doaj.org/article/e867d770eb3d4af1a33559bd67c682cc
Autor:
Elena Roger, Christos E. Chadjichristos, Panagiotis Kavvadas, Gareth W. Price, Chelsy L. Cliff, Safia Hadjadj, Jessy Renciot, Paul E. Squires, Claire E. Hills
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-20 (2023)
Abstract Background Without a viable cure, chronic kidney disease is a global health concern. Inflammatory damage in and around the renal tubules dictates disease severity and is contributed to by multiple cell types. Activated in response to danger
Externí odkaz:
https://doaj.org/article/e48577cddf834d8685f737c5c38985e6
Publikováno v:
Health Research Policy and Systems, Vol 21, Iss 1, Pp 1-19 (2023)
Abstract Background There is growing evidence that context mediates the effects of implementation interventions intended to increase healthcare professionals’ use of research evidence in clinical practice. However, conceptual clarity about what com
Externí odkaz:
https://doaj.org/article/f983a49fc051423383b21923cbb60378
Autor:
Areti Angeliki Veroniki, Charlene Soobiah, Vera Nincic, Yonda Lai, Patricia Rios, Heather MacDonald, Paul A. Khan, Marco Ghassemi, Fatemeh Yazdi, Ross C. Brownson, David A. Chambers, Lisa R. Dolovich, Annemarie Edwards, Paul P. Glasziou, Ian D. Graham, Brenda R. Hemmelgarn, Bev J. Holmes, Wanrudee Isaranuwatchai, France Legare, Jessie McGowan, Justin Presseau, Janet E. Squires, Henry T. Stelfox, Lisa Strifler, Trudy Van der Weijden, Christine Fahim, Andrea C. Tricco, Sharon E. Straus
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-20 (2023)
Abstract Background Chronic disease management (CDM) through sustained knowledge translation (KT) interventions ensures long-term, high-quality care. We assessed implementation of KT interventions for supporting CDM and their efficacy when sustained
Externí odkaz:
https://doaj.org/article/06a522014fe448ddb6f748174312c3a7
Autor:
Wilmer J. Santos, Alison M. Hutchinson, Tamara Rader, Ian D. Graham, Vanessa Watkins, Ligyana Korki de Candido, Megan Greenough, Janet E. Squires
Publikováno v:
BMC Research Notes, Vol 16, Iss 1, Pp 1-10 (2023)
Abstract Objectives To describe our experience with using a methodological outcomes measurement search filter (precise and sensitive versions of a filter designed to locate articles that report on psychometric properties of measurement tools) and cit
Externí odkaz:
https://doaj.org/article/ef9da8b3f38649dba8e77434087f7177
Autor:
Laura D. Aloisio, Nicole Graham, Doris Grinspun, Shanoja Naik, Mary Coughlin, Christina Medeiros, Heather McConnell, Anne Sales, Susan McNeill, Wilmer J. Santos, Janet E. Squires
Publikováno v:
Heliyon, Vol 9, Iss 9, Pp e19983- (2023)
Background: The use of best practice guidelines (BPGs) has the potential to decrease the gap between best evidence and nursing and healthcare practices. We conducted an exploratory mixed method study to identify strategies, processes, and indicators
Externí odkaz:
https://doaj.org/article/83a2ef29acbd40f6b5b109a6698b33e1
Publikováno v:
Implementation Science Communications, Vol 3, Iss 1, Pp 1-48 (2022)
Abstract Background Champions have been documented in the literature as an important strategy for implementation, yet their effectiveness has not been well synthesized in the health care literature. The aim of this systematic review was to determine
Externí odkaz:
https://doaj.org/article/575af875ef7444b1bb9994e5ebdd0d58
Autor:
Rodrigo M. Florentino, Qin Li, Michael C. Coard, Nils Haep, Takashi Motomura, Ricardo Diaz‐Aragon, Lanuza A. P. Faccioli, Sriram Amirneni, Zehra N. Kocas‐Kilicarslan, Alina Ostrowska, James E. Squires, Andrew P. Feranchak, Alejandro Soto‐Gutierrez
Publikováno v:
Hepatology Communications, Vol 6, Iss 7, Pp 1561-1573 (2022)
Abstract The initial creation of human‐induced pluripotent stem cells (iPSCs) set the foundation for the future of regenerative medicine. Human iPSCs can be differentiated into a variety of cell types in order to study normal and pathological molec
Externí odkaz:
https://doaj.org/article/70dc40a2ee5040eebed9cfab76e9f4ff