Zobrazeno 1 - 10
of 16
pro vyhledávání: '"P. E. O. Williams"'
Autor:
Vida A. Kukula, Elizabeth Awini, Bidisha Ghosh, Veronica Apetorgbor, Ruth Zielinski, Georgina Amankwah, Winfred K. Ofosu, Katherine James, John E. O. Williams, Jody R. Lori, Cheryl A. Moyer
Publikováno v:
BMC Pregnancy and Childbirth, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background As utilization of individual antenatal care (I-ANC) has increased throughout sub-Saharan Africa, questions have arisen about whether individual versus group-based care might yield better outcomes. We implemented a trial of group-b
Externí odkaz:
https://doaj.org/article/dcc79acd496e4f77b0fafcce132df1ae
Autor:
Jody R Lori, John E O Williams, Vida A Kukula, Veronica E A Apetorgbor, Elizabeth A Awini, Georgina Amankwah, Ruth Zielinski, Nancy Lockhart, Katherine H James, Cheryl A Moyer
Publikováno v:
JMIR Research Protocols, Vol 11, Iss 9, p e40828 (2022)
BackgroundWhile group antenatal care (ANC) has been delivered and studied in high-income countries for over a decade, it has only recently been introduced as an alternative to individual care in sub-Saharan Africa. Although the experimental design of
Externí odkaz:
https://doaj.org/article/70471073ad0a46daa09d3f03f37f8373
Publikováno v:
Scopus-Elsevier
1. The response to romazarit, a disease modifying anti-rheumatoid agent, was observed in patients with rheumatoid arthritis (RA) in a double-blind placebo controlled study. 2. Two hundred and twenty-four patients were recruited from 11 centres and tr
Publikováno v:
British Journal of Clinical Pharmacology. 35:255-260
1. The aim of this study was to estimate an oral dosage regimen of 2FddC giving peak plasma drug concentrations close to the antiretroviral IC50 of 150 ng ml-1. 2. A total of 55 doses (40 intravenous infusions and 15 oral solutions) were given to 21
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 15:63-67
The pharmacokinetics of cilazapril and its active metabolite cilazaprilat in plasma were investigated in an open study of 13 healthy male volunteers, aged 18 to 43 years. One capsule containing 2.5 mg cilazapril was administered to each volunteer dai
Autor:
H. A. Bird, J. Bentley, P. S. Helliwell, P. E. O. Williams, G. J. Muirhead, S. Minty, A. York
Publikováno v:
Biopharmaceuticsdrug disposition. 13(2)
Romazarit is a new drug for which animal pharmacology suggests a disease-modifying action in rheumatoid arthritis (RA). These animal studies predict that plasma romazarit concentrations within the range 50-100 mg l-1 may be required for efficacy in t
Publikováno v:
European journal of drug metabolism and pharmacokinetics. 15(4)
Forty-four healthy male volunteers participated in an investigation of the pharmacokinetics and tolerance of single oral doses of romazarit, a potential disease-modifying antirheumatic drug. The study design involved single oral doses in ascending se
Publikováno v:
Antimicrobial agents and chemotherapy. 25(1)
Cefuroxime axetil is a new orally absorbed prodrug of the antibiotic cefuroxime. The results of pharmacological studies in 52 healthy volunteers are presented. Intact cefuroxime axetil was not detected in the systemic circulation, indicating that dee
Autor:
P. E. O. Williams, R. J. Francis, A. N. Brown, Eric Rosenthal, P. V. L. Curry, S. Rajaguru, J. Steiner
1. The pharmacokinetics of cilazapril and the inhibition of angiotensin converting enzyme (ACE) were investigated in 10 patients with congestive heart failure, NYHA class II-III, receiving diuretics with or without digoxin. 2. Patients received 0.5 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::620b5eb31e8bc2a651cd3b9637aece61
https://europepmc.org/articles/PMC1379757/
https://europepmc.org/articles/PMC1379757/
Autor:
R. J. Gilbert, P. E. O. Williams
Publikováno v:
British journal of clinical pharmacology. 23(5)
An antiplaque toothpaste containing 0.2% (w/w) triclosan significantly inhibited overnight plaque growth in 12 human volunteers. After use of a 1 g quantity of the toothpaste containing 0.2% (w/w) [3H]-triclosan, 36.3 +/- 1.4% of the triclosan was re