Zobrazeno 1 - 10
of 242
pro vyhledávání: '"P. E. Murray"'
Autor:
Clare E. Murray, Anand V. R. Kornepati, Carlos Ontiveros, Yiji Liao, Bárbara de la Peña Avalos, Cody M. Rogers, Zexuan Liu, Yilun Deng, Haiyan Bai, Suresh Kari, Alvaro S. Padron, Jacob T. Boyd, Ryan Reyes, Curtis A. Clark, Robert S. Svatek, Rong Li, Yanfen Hu, Meiling Wang, José R. Conejo-Garcia, Lauren A. Byers, Kavya Ramkumar, Anil K. Sood, Jung-Min Lee, Christin E. Burd, Ratna K. Vadlamudi, Harshita B. Gupta, Weixing Zhao, Eloïse Dray, Patrick Sung, Tyler J. Curiel
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-24 (2024)
Abstract Background Aside from the canonical role of PDL1 as a tumour surface-expressed immune checkpoint molecule, tumour-intrinsic PDL1 signals regulate non-canonical immunopathological pathways mediating treatment resistance whose significance, me
Externí odkaz:
https://doaj.org/article/324b033e9fa34bbcab45721b8054a03a
Autor:
J. E. Murray, L. Warwick, H. Brindley, A. Last, P. Quigley, A. Rochester, A. Dewar, D. Cummins
Publikováno v:
Atmospheric Measurement Techniques, Vol 17, Pp 4757-4775 (2024)
The Far-INfrarEd Spectrometer for Surface Emissivity (FINESSE) instrument combines a commercial Bruker EM27 spectrometer with a front-end viewing and calibration rig developed at Imperial College London. FINESSE is specifically designed to enable acc
Externí odkaz:
https://doaj.org/article/5f07dd2ea12b4b06acd20d8285f8a9c2
Publikováno v:
Atmospheric Measurement Techniques, Vol 17, Pp 4777-4787 (2024)
In this paper, we describe a method for retrieving the surface emissivity of specular surfaces across the wavenumber range of 400–1600 cm−1 using novel radiance measurements of the Far-INfrarEd Spectrometer for Surface Emissivity (FINESSE) instru
Externí odkaz:
https://doaj.org/article/ea1cbd17cecf402d9db220d54d339457
Autor:
Surendra Reddy Gundam, Aditya Bansal, Manasa Kethamreddy, Sujala Ghatamaneni, Val J. Lowe, Melissa E. Murray, Mukesh K. Pandey
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Non-invasive imaging of GSK-3 expression in the brain will help to understand the role of GSK-3 in disease pathology and progression. Herein, we report the radiosynthesis and evaluation of two novel isonicotinamide based 18F labeled PET prob
Externí odkaz:
https://doaj.org/article/b3c06bb0c51f45d7a7242fa17ba530af
Autor:
Jayne E. Murray, Emanuele Valli, Giorgio Milazzo, Chelsea Mayoh, Andrew J. Gifford, Jamie I. Fletcher, Chengyuan Xue, Nisitha Jayatilleke, Firoozeh Salehzadeh, Laura D. Gamble, Jourdin R. C. Rouaen, Daniel R. Carter, Helen Forgham, Eric O. Sekyere, Joanna Keating, Georgina Eden, Sophie Allan, Stephanie Alfred, Frances K. Kusuma, Ashleigh Clark, Hannah Webber, Amanda J. Russell, Antoine de Weck, Benjamin T. Kile, Martina Santulli, Piergiuseppe De Rosa, Emmy D. G. Fleuren, Weiman Gao, Lorna Wilkinson-White, Jason K. K. Low, Joel P. Mackay, Glenn M. Marshall, Douglas J. Hilton, Federico M. Giorgi, Jan Koster, Giovanni Perini, Michelle Haber, Murray D. Norris
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract MYCN oncogene amplification is frequently observed in aggressive childhood neuroblastoma. Using an unbiased large-scale mutagenesis screen in neuroblastoma-prone transgenic mice, we identify a single germline point mutation in the transcript
Externí odkaz:
https://doaj.org/article/ee532e0c05a8415d9de099a04d9f475c
Autor:
Özkan İş, Xue Wang, Joseph S. Reddy, Yuhao Min, Elanur Yilmaz, Prabesh Bhattarai, Tulsi Patel, Jeremiah Bergman, Zachary Quicksall, Michael G. Heckman, Frederick Q. Tutor-New, Birsen Can Demirdogen, Launia White, Shunsuke Koga, Vincent Krause, Yasuteru Inoue, Takahisa Kanekiyo, Mehmet Ilyas Cosacak, Nastasia Nelson, Annie J. Lee, Badri Vardarajan, Richard Mayeux, Naomi Kouri, Kaancan Deniz, Troy Carnwath, Stephanie R. Oatman, Laura J. Lewis-Tuffin, Thuy Nguyen, for the Alzheimer’s Disease Neuroimaging Initiative, Minerva M. Carrasquillo, Jonathan Graff-Radford, Ronald C. Petersen, Clifford R. Jr Jack, Kejal Kantarci, Melissa E. Murray, Kwangsik Nho, Andrew J. Saykin, Dennis W. Dickson, Caghan Kizil, Mariet Allen, Nilüfer Ertekin-Taner
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract To uncover molecular changes underlying blood-brain-barrier dysfunction in Alzheimer’s disease, we performed single nucleus RNA sequencing in 24 Alzheimer’s disease and control brains and focused on vascular and astrocyte clusters as mai
Externí odkaz:
https://doaj.org/article/0f4d86fabcd9496f8761615d7234bc5b
Autor:
Molly Noel Rymes, Rebecca Rasmussen, Pablo A. Garcia-Chevesich, Katie Burgert, Jean Long, Elsie McBride, Gisella Martínez, Kattia Martínez, Teresa Tejada, Kyle E. Murray, Gary Vanzin, Jonathan O. Sharp, John E. McCray
Publikováno v:
Data in Brief, Vol 56, Iss , Pp 110770- (2024)
Though surface water quality has been monitored in southern Peru over the past and current century, it has been implemented by multiple organizations. The data lacks a centralized repository and access requires logistical and temporal hurdles associa
Externí odkaz:
https://doaj.org/article/90ae82c167b44c009cafea1623e25664
Autor:
Molly E. Murray, Beatriz G. Goncalves, Mary A. Biggs, Sophia A. Frantzeskos, Charlotta G. Lebedenko, Ipsita A. Banerjee
Publikováno v:
Applied Biological Chemistry, Vol 67, Iss 1, Pp 1-23 (2024)
Abstract The Nociceptin/orphanin FQ peptide (NOP) receptor is considered a member of the opioid receptor subfamily of G-protein coupled receptors (GPCRs) which has been shown to be present in many parts of the central nervous system (CNS). It plays b
Externí odkaz:
https://doaj.org/article/75297129c8cd409c91c61a8d500d799f
Publikováno v:
PLOS Digital Health, Vol 3, Iss 8, p e0000549 (2024)
Despite the emergence of antimicrobial-resistant (AMR) strains of Neisseria gonorrhoeae, the treatment of gonorrhea remains empiric and according to standardized guidelines, which are informed by the national prevalence of resistant strains. Yet, the
Externí odkaz:
https://doaj.org/article/c10e0d1123444099826bfa922e9e4fce
Impact of APOE on amyloid and tau accumulation in argyrophilic grain disease and Alzheimer’s disease
Autor:
Ana-Caroline Raulin, Sydney V. Doss, Michael G. Heckman, Emily C. Craver, Zonghua Li, Tadafumi C. Ikezu, Hiroaki Sekiya, Chia-Chen Liu, Yuka A. Martens, Cassandra L. Rosenberg, Lindsey A. Kuchenbecker, Michael DeTure, R. Ross Reichard, Aivi T. Nguyen, Eleni Constantopoulos, Rachel A. Larsen, Emmaline K. Kounaves, Melissa E. Murray, Dennis W. Dickson, Ronald C. Petersen, Guojun Bu, Takahisa Kanekiyo
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-16 (2024)
Abstract Alzheimer’s disease (AD), characterized by the deposition of amyloid-β (Aβ) in senile plaques and neurofibrillary tangles of phosphorylated tau (pTau), is increasingly recognized as a complex disease with multiple pathologies. AD sometim
Externí odkaz:
https://doaj.org/article/8f5535e35e724bf6989bb41e302e114e