Zobrazeno 1 - 10
of 95
pro vyhledávání: '"P. E. Kolattukudy"'
Autor:
Wei Shen, Xiaoguang Wang, Meiqi Tang, Lan Yao, Chenyu Wan, Jianli Niu, Pappachan E. Kolattukudy, Zhuqing Jin
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 164, Iss , Pp 114914- (2023)
Huoluo Xiaoling Pellet (HXP), a Chinese patent medicine, is commonly administered for the treatment of treat ischemic strokes. MCPIP1, an inducible suppressor of the inflammatory response, is a regulator of microglial M2 polarization. This study aime
Externí odkaz:
https://doaj.org/article/8dbed743abd943389109a59b427de7fb
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Inflammatory response is a host-protective mechanism against tissue injury or infections, but also has the potential to cause extensive immunopathology and tissue damage, as seen in many diseases, such as cardiovascular diseases, neurodegenerative di
Externí odkaz:
https://doaj.org/article/dbb3bbfd5fb345ac8c4507a88833c26c
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Tetramethylpyrazine (TMP), a prominent ingredient of Chinese herb Ligusticum chuanxiong Hort, is known to suppress neuroinflammation and protect blood-brain barrier (BBB) integrity. We investigated whether monocyte chemotactic protein-induced protein
Externí odkaz:
https://doaj.org/article/41219dd1c1a042579afeb3ac17368b12
Autor:
Tam T. Quach, Nathalie Auvergnon, Rajesh Khanna, Marie-Françoise Belin, Papachan E. Kolattukudy, Jérome Honnorat, Anne-Marie Duchemin
Publikováno v:
Brain Sciences, Vol 8, Iss 11, p 196 (2018)
Collapsin response mediator proteins (CRMPs) are highly expressed in the brain during early postnatal development and continue to be present in specific regions into adulthood, especially in areas with extensive neuronal plasticity including the hipp
Externí odkaz:
https://doaj.org/article/c10889015915448b86004365f57caeb7
Autor:
Nidhi Kapoor, Santosh Pawar, Tatiana D Sirakova, Chirajyoti Deb, William L Warren, Pappachan E Kolattukudy
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53657 (2013)
Tuberculosis (TB) is responsible for death of nearly two million people in the world annually. Upon infection, Mycobacterium tuberculosis (Mtb) causes formation of granuloma where the pathogen goes into dormant state and can live for decades before r
Externí odkaz:
https://doaj.org/article/6507bba0d87248f99784c00d7e038971
Autor:
Dheeraj Verma, Shuangxia Jin, Anderson Kanagaraj, Nameirakpam D Singh, Jaiyanth Daniel, Pappachan E Kolattukudy, Michael Miller, Henry Daniell
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57187 (2013)
In order to produce low-cost biomass hydrolyzing enzymes, transplastomic lines were generated that expressed cutinase or swollenin within chloroplasts. While swollenin expressing plants were homoplasmic, cutinase transplastomic lines remained heterop
Externí odkaz:
https://doaj.org/article/1845e59fa40347898943fd9f3563a06a
Autor:
Tatiana D Sirakova, Chirajyoti Deb, Jaiyanth Daniel, Harminder D Singh, Hedia Maamar, Vinod S Dubey, Pappachan E Kolattukudy
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51641 (2012)
Mycobacterium tuberculosis (Mtb) is known to produce wax esters (WE) when subjected to stress. However, nothing is known about the enzymes involved in biosynthesis of WE and their role in mycobacterial dormancy. We report that two putative Mtb fatty
Externí odkaz:
https://doaj.org/article/1b159b0d90014439beae394c46d77a4b
Publikováno v:
PLoS Pathogens, Vol 7, Iss 6, p e1002093 (2011)
Two billion people are latently infected with Mycobacterium tuberculosis (Mtb). Mtb-infected macrophages are likely to be sequestered inside the hypoxic environments of the granuloma and differentiate into lipid-loaded macrophages that contain triacy
Externí odkaz:
https://doaj.org/article/5060ff77689344c88b673aa65771967b
Autor:
Chirajyoti Deb, Chang-Muk Lee, Vinod S Dubey, Jaiyanth Daniel, Bassam Abomoelak, Tatiana D Sirakova, Santosh Pawar, Linda Rogers, Pappachan E Kolattukudy
Publikováno v:
PLoS ONE, Vol 4, Iss 6, p e6077 (2009)
BACKGROUND:Mycobacterium tuberculosis (Mtb) becomes dormant and phenotypically drug resistant when it encounters multiple stresses within the host. Inability of currently available drugs to kill latent Mtb is a major impediment to curing and possibly
Externí odkaz:
https://doaj.org/article/9f4c73837da34623ac4e73aad3774336
Publikováno v:
PLoS ONE, Vol 3, Iss 8, p e2880 (2008)
Previously, we have identified a novel CCCH zinc finger protein family as negative regulators of macrophage activation. To gain an overall insight into the entire CCCH zinc finger gene family and to evaluate their potential role in macrophage activat
Externí odkaz:
https://doaj.org/article/833773d9dd944cb7996d3c52334874f6