Zobrazeno 1 - 6
of 6
pro vyhledávání: '"P. E. Keeting"'
Autor:
P. E. Keeting, M. B. Rice, F. J. Secreto, M. Pacurari, A. Grover, M. Kantorow, J. D. Blaha, A. P. Bidwai
Publikováno v:
Calcified tissue international. 73(6)
Reports that estrogen treatment modulates arachidonic acid metabolism by bone and bone cells are found in the literature. However, conflicting indications of the relationship that exists between estrogen and arachidonic acid metabolism emerge from th
Publikováno v:
Journal of cellular biochemistry. 71(1)
The eicosanoids, including prostaglandin E2 (PGE2) and other bioactive arachidonic acid metabolites, are important local mediators of bone remodeling. Presumably, the limited or excessive synthesis of the eicosanoids could compromise bone homeostasis
Publikováno v:
Journal of cellular biochemistry. 68(2)
The steroid derivative 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) is a regulator of bone biology, and there is evidence that 1,25(OH)2D3 modulates arachidonic acid metabolism in osteoblastic cell model systems and in bone organ cultures. In the present s
Publikováno v:
Journal of cellular biochemistry. 64(4)
Prostaglandin (PG) biosynthesis by cytokine stimulated normal adult human osteoblast-like (hOB) cells was evaluated by thin layer chromatography, high performance liquid chromatography, and specific immunoassays. PGE2 was the predominant PG formed un
Publikováno v:
Journal of cellular biochemistry. 60(2)
Eicosanoids are multifunctional autocrine/paracrine regulators of bone that are enzymatically derived from arachidonic acid (AA). The rate-limiting step in the eicosanoid biosynthetic pathways may be the release of AA from membrane glycerophospholipi
Publikováno v:
Current eye research. 10(4)
Evidence is presented indicating that young rat lens has the capacity to synthesize 12(S)-hydroxyeicosatetraenoic acid (12(S)-HETE) from exogenous arachidonic acid (AA). A 9,000 xg supernatant prepared from 15 day old rat lenses, when incubated with