Zobrazeno 1 - 10
of 17
pro vyhledávání: '"P. E. Grundy"'
Autor:
Erin E. Grundy, Lauren C. Shaw, Loretta Wang, Abigail V. Lee, James Castro Argueta, Daniel J. Powell, Mario Ostrowski, R. Brad Jones, C. Russell Y. Cruz, Heather Gordish-Dressman, Nicole P. Chappell, Catherine M. Bollard, Katherine B. Chiappinelli
Publikováno v:
Mobile DNA, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Transposable elements (TEs) are often expressed at higher levels in tumor cells than normal cells, implicating these genomic regions as an untapped pool of tumor-associated antigens. In ovarian cancer (OC), protein from the TE ERV-K is frequ
Externí odkaz:
https://doaj.org/article/ae60226c036b4df8a06919f4dc2441a1
Autor:
Dae Joong Kim, Swetha Anandh, Jamie L. Null, Piotr Przanowski, Sanchita Bhatnagar, Pankaj Kumar, Sarah E. Shelton, Erin E. Grundy, Katherine B. Chiappinelli, Roger D. Kamm, David A. Barbie, Andrew C. Dudley
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Targeting DNA methyltransferase 1 (DNMT1) has immunomodulatory and anti-neoplastic activity, especially when paired with cancer immunotherapies. Here we explore the immunoregulatory functions of DNMT1 in the tumor vasculature of female mice.
Externí odkaz:
https://doaj.org/article/5ba899d284fd457f8d38e9095d8fd28e
Autor:
Samantha Gadd, Vicki Huff, Chiang-Ching Huang, E. Cristy Ruteshouser, Jeffrey S. Dome, Paul E. Grundy, Norman Breslow, Lawrence Jennings, Daniel M. Green, J. Bruce Beckwith, Elizabeth J. Perlman
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 8, Pp 742-756 (2012)
Wilms tumors (WT) have provided broad insights into the interface between development and tumorigenesis. Further understanding is confounded by their genetic, histologic, and clinical heterogeneity, the basis of which remains largely unknown. We eval
Externí odkaz:
https://doaj.org/article/645ccf46a1b8404b9235379f5a0e3b1f
Autor:
Marianne K-H. Kim, Jacqueline M. Mason, Chi-Ming Li, Windy Berkofsky-Fessler, Le Jiang, Divaker Choubey, Paul E. Grundy, Benjamin Tycko, Jonathan D. Licht
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 10, Iss 1, Pp 69-78 (2008)
The Wilms tumor gene (WT1) is mutated or deleted in patients with heredofamilial syndromes associated with the development of Wilms tumors, but is infrequently mutated in sporadic Wilms tumors. By comparing the microarray profiles of syndromic versus
Externí odkaz:
https://doaj.org/article/f7497fb99bff42bd8af8a975efc1d754
Autor:
Jane E Grundy
Publikováno v:
Canadian Journal of Infectious Diseases, Vol 4, Iss Suppl C, Pp 11-17 (1993)
Cytomegalovirus (CMV) infection is an important cause of morbidity and mortality in the immunocompromised; however, even within this group of patients, infection with CMV is not synonymous with disease. A number of factors affect the pathogenicity of
Externí odkaz:
https://doaj.org/article/2dce75d20be14682b4685901e3053b00
Autor:
A. C. V. Krepischi, M. Maschietto, E. N. Ferreira, A. G. Silva, S. S. Costa, I. W. Cunha, B. D. F. Barros, P. E. Grundy, C. Rosenberg, D. M. Carraro
List of genes selected for copy number validation of 9 focal rearrangements using real-time quantitative PCR (qPCR) with TaqMan Gene Copy Number assays. (DOC 34Â kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9b215c168705daec0028a80de2b7cba
Autor:
R. Newbury, P. E. Grundy, Norman E. Breslow, Robert C. Shamberger, Max J. Coppes, G J D'Angio, Peter F. Coccia, J. B. Beckwith, Marcio H. Malogolowkin, Elizabeth J. Perlman, G. M. Haase, M. Donaldson, M. L. Ritchey, M. Kletzel, D. Weeks, G. Tomlinson, R. Macklis, Daniel M. Green, P. Shearer, V. Huff, P. R.M. Thomas, R. Weetman
Publikováno v:
Journal of Clinical Oncology. 19:3719-3724
PURPOSE: Children younger than 24 months with small (< 550 g), favorable histology (FH) Wilms tumors (WTs) were shown in a pilot study to have an excellent prognosis when treated with nephrectomy only. PATIENTS AND METHODS: A study of nephrectomy onl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40aad494d1ba635dabf58d833805d155
https://doi.org/10.1200/jco.2001.19.17.3719
https://doi.org/10.1200/jco.2001.19.17.3719
Autor:
P. R.M. Thomas, G J D'Angio, G. M. Haase, Daniel M. Green, P. E. Grundy, P Kelalis, S Shochat, J Z Finklestein, Norman E. Breslow, T Kim, M. L. Ritchey, J. B. Beckwith
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 16(12)
PURPOSE National Wilms' Tumor Study (NWTS)-4 was designed to evaluate the efficacy, toxicity, and cost of the administration of different regimens for the treatment of Wilms' tumor (WT). PATIENTS AND METHODS Between August 6, 1986 and September 1, 19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a7bde44b953179746fe8ede869f7b73
https://pubmed.ncbi.nlm.nih.gov/9850017
https://pubmed.ncbi.nlm.nih.gov/9850017
Publikováno v:
Cancer research. 58(22)
Congenital mesoblastic nephroma (CMN) is an infantile spindle cell tumor of the kidney that is subdivided into "classical" and "cellular" forms based on the degree of cellularity and mitotic activity. The histogenesis of CMN remains obscure, but rela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::da3860b2af09b2fc4934ec5207e3e847
https://pubmed.ncbi.nlm.nih.gov/9823307
https://pubmed.ncbi.nlm.nih.gov/9823307
Autor:
F P, Li, N E, Breslow, J M, Morgan, M, Ghahremani, G A, Miller, P E, Grundy, D M, Green, L R, Diller, J, Pelletier
Publikováno v:
Medical and pediatric oncology. 27(5)
We conducted a comparative study of the prevalence of germline WT1 mutations in patients with Wilms' tumor. Patients in Group 1 have familial Wilms' tumor, bilateral disease, associated urogenital anomalies, and/or second cancers. Those in Group 2 ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0a849ff5f9c0889365a9905a9918aff0
https://pubmed.ncbi.nlm.nih.gov/8827066
https://pubmed.ncbi.nlm.nih.gov/8827066