Zobrazeno 1 - 10
of 22
pro vyhledávání: '"P. E. Ebong"'
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
While cardiovascular disease, cancer, and human immunodeficiency virus (HIV) mortality rates have decreased over the past 20 years, Alzheimer’s Disease (AD) deaths have risen by 145% since 2010. Despite significant research efforts, effective AD tr
Externí odkaz:
https://doaj.org/article/5c1431ffb7694ce883eb843c68ac6bea
Autor:
Mohammad Hamrangsekachaee, Ke Wen, Narges Yazdani, Rebecca K. Willits, Sidi A. Bencherif, Eno E. Ebong
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Glycocalyx (GCX) is a carbohydrate-rich structure that coats the surface of endothelial cells (ECs) and lines the blood vessel lumen. Mechanical perturbations in the vascular environment, such as blood vessel stiffness, can be transduced and sent to
Externí odkaz:
https://doaj.org/article/55dfc8a990464726a1d6332cc057b243
Autor:
Godwin E. Asenye, Toluwanimi E. Akinleye, Uwem E. George, Bob I. Mgbeje, Olubusuyi M. Adewumi, Johnson A. Adeniji, Omonike O. Ogbole, Patrick E. Ebong
Publikováno v:
Phytomedicine Plus, Vol 3, Iss 2, Pp 100423- (2023)
Background: Over the years, the morbidity and mortality due to cancer have continued to increase worldwide. Plants are well utilized in Nigeria ethno-medicine for cancer treatment. However, scientific evidence, particularly at the molecular level, ha
Externí odkaz:
https://doaj.org/article/e6aa5f3392f6402b804eb5cecfd2fbec
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Ischemic stroke, a major cause of mortality in the United States, often contributes to disruption of the blood-brain barrier (BBB). The BBB along with its supportive cells, collectively referred to as the “neurovascular unit,” is the brain’s mu
Externí odkaz:
https://doaj.org/article/ef4c5211bc0245419964cc5e9735bc7d
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-20 (2018)
Abstract Background Endothelial-dependent atherosclerosis develops in a non-random pattern in regions of vessel bending and bifurcations, where blood flow exhibits disturbed flow (DF) patterns. In contrast, uniform flow (UF), normal endothelium, and
Externí odkaz:
https://doaj.org/article/5687852e32bd4460ab6b9a526ced06d0
Autor:
Ronodeep Mitra, Ju Qiao, Sudharsan Madhavan, Gerard L. O’Neil, Bailey Ritchie, Praveen Kulkarni, Srinivas Sridhar, Anne L. van de Ven, Erica M. Cherry Kemmerling, Craig Ferris, James A. Hamilton, Eno E. Ebong
Publikováno v:
Translational Medicine Communications, Vol 3, Iss 1, Pp 1-15 (2018)
Abstract Background and aims Endothelial surface glycocalyx shedding plays a role in endothelial dysfunction and increases vessel wall permeability, which can lead to inflammation and atherogenesis. We sought to elucidate whether a high fat diet (HFD
Externí odkaz:
https://doaj.org/article/36a6d30b86254938a457135e3850f435
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186116 (2017)
Vasculoprotective endothelium glycocalyx (GCX) shedding plays a critical role in vascular disease. Previous work demonstrated that GCX degradation disrupts endothelial cell (EC) gap junction connexin (Cx) proteins, likely blocking interendothelial mo
Externí odkaz:
https://doaj.org/article/c4b68d44eb2748e2ac5cf5bbab858ac7
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43168 (2012)
It is widely believed that glycosaminoglycans (GAGs) and bound plasma proteins form an interconnected gel-like structure on the surface of endothelial cells (the endothelial glycocalyx layer-EGL) that is stabilized by the interaction of its component
Externí odkaz:
https://doaj.org/article/474329e79dbc491ba8325c84e0b69ccc
Publikováno v:
Journal of Advances in Medicine and Medical Research.
Aim: The study evaluated the effects of the combined extracts of Vernonia amygdalina (VA) and Gongronema latifolium (GL) on pancreatic GLUT 2 expression and caspase 3 activity in streptozotocin (STZ, 45 mg/Kg)-induced diabetic rats. Study Design: Fif
Publikováno v:
Andrologia. 50:e13050
Previous studies showed that exposure to stress or nicotine induced reproductive impairment in male rats. Here, we assessed the effect of an antioxidant (vitamin E) on nicotine-, stress- and nicotine + stress-induced reproductive impairment in male r