Zobrazeno 1 - 10
of 38
pro vyhledávání: '"P. E. Daddona"'
Autor:
Mahmoud Ameri, Miryam Kadkhodayan, Joe Nguyen, Joseph A. Bravo, Rebeca Su, Kenneth Chan, Ahmad Samiee, Peter E. Daddona
Publikováno v:
Pharmaceutics, Vol 6, Iss 2, Pp 220-234 (2014)
This study evaluated the feasibility of coating formulated recombinant human growth hormone (rhGH) on a titanium microneedle transdermal delivery system, Zosano Pharma (ZP)-hGH, and assessed preclinical patch delivery performance. Formulation rheolog
Externí odkaz:
https://doaj.org/article/a9a52ca459384111ab5c2451fe2d92a3
Publikováno v:
Journal of Infectious Diseases. 168:1429-1435
Specific binding of two monoclonal IgM antibodies previously investigated as therapeutic agents for treating gram-negative septic shock, HA-1A and E5, was assessed with respect to lipid A and lipopolysaccharide (LPS). Both antibodies bound to lipid A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::734fd31af530aa0b0e5a98e13fef5aee
https://doi.org/10.1093/infdis/168.6.1429
https://doi.org/10.1093/infdis/168.6.1429
Autor:
P E, Daddona
Publikováno v:
Current opinion in drug discoverydevelopment. 2(2)
Controlled delivery of macromolecular drugs, such as peptides, proteins, oligonucleotides and polysaccharides remains a major challenge. While these drugs can be administered by subcutaneous injection or intravenous infusion, more convenient, painles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::645e37e10bda2626bd266a40a97d6f47
https://pubmed.ncbi.nlm.nih.gov/19649943
https://pubmed.ncbi.nlm.nih.gov/19649943
Autor:
Margreet Jonker, G. Treacy, K. Y. Pak, A. F. Lobuglio, J. Iuliucci, S.H. Tam, E. Wilson, K. Bakker, P. van Eerd, W. Slingerland, P. E. Daddona, G. Riethmüller, Peter Rieber
Publikováno v:
Clinical and experimental immunology. 93(3)
SUMMARY Chimeric M-T412 (cM-T412). an anti-CD4 antibody, was tolerated in chimpanzees at a dosage of 5 mg/kg per day for up to 7 consecutive days, or 5 mg/kg per dose, twice weekly for 4 weeks. All cM-T412-treated chimpanzees showed a prolonged CD4 c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5020e7857f67bfc81adb3fcb0dd3ec8
https://pubmed.ncbi.nlm.nih.gov/8103714
https://pubmed.ncbi.nlm.nih.gov/8103714
Autor:
J E, Looney, D M, Knight, M, Arevalo-Moore, H, Trinh, K Y, Pak, M R, Dalesandro, E P, Rieber, G, Riethmuller, P E, Daddona, J, Ghrayeb
Publikováno v:
Human antibodies and hybridomas. 3(4)
The use of murine anti-CD4 monoclonal antibodies (MAbs) has shown considerable promise for the treatment of allograft rejection and rheumatoid arthritis. We have constructed mouse-human anti-CD4 antibodies with the goal of increasing their clinical p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e4fd11ab40b43caed2034c6f467d65dd
https://pubmed.ncbi.nlm.nih.gov/1477300
https://pubmed.ncbi.nlm.nih.gov/1477300
Autor:
K Y, Pak, M A, Nedelman, W E, Fogler, S H, Tam, E, Wilson, L J, Van Haarlem, R, Colognola, S O, Warnaar, P E, Daddona
Publikováno v:
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology. 18(5)
The 323/A3 murine monoclonal antibody, initially described as reactive to breast carcinomas, is found by immunohistological analyses to have broad cross reactivity with adenocarcinomas of diverse histologic origin. The 323/A3 antigen is similar to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1caf6879d2ada9c41a01b77f50cc1a9e
https://pubmed.ncbi.nlm.nih.gov/1917518
https://pubmed.ncbi.nlm.nih.gov/1917518
Autor:
Otto Braun-Falco, Peter Rieber, Jörg C. Prinz, G. Riethmüller, Christian Reiter, Michael Meurer, P. E. Daddona
Publikováno v:
The Lancet. 338:320-321
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fe5b785dd4fef16f0ebca8acd08e4c7
https://doi.org/10.1016/0140-6736(91)90464-z
https://doi.org/10.1016/0140-6736(91)90464-z
Autor:
P E Daddona
Publikováno v:
Journal of Biological Chemistry. 256:12496-12501
In this study, the properties and rate of turnover of adenosine deaminase are compared in cultured human T and B lymphoblast cell lines. 1) Relative to B lymphoblasts, the level of adenosine deaminase activity in extracts of T lymphoblast cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06114579b24f31dee50e48e79fd041f5
https://doi.org/10.1016/s0021-9258(18)43302-9
https://doi.org/10.1016/s0021-9258(18)43302-9
Publikováno v:
The Journal of Immunology. 138:4534-4538
Mouse monoclonal antibody 17-1A is specific for an antigen expressed on cells of human gastrointestinal malignancies and has been used in radioimmune imaging and therapy trials for patients with colon and pancreatic cancer. The cell line SG3/5 was ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1dbb1e10c3580f04fbaad3eee874c9e1
https://doi.org/10.4049/jimmunol.138.12.4534
https://doi.org/10.4049/jimmunol.138.12.4534
Autor:
D R, Shaw, G, Harrison, L K, Sun, C, Shearman, J, Ghrayeb, S, McKinney, P E, Daddona, A F, LoBuglio
Publikováno v:
Journal of biological response modifiers. 7(2)
The mouse monoclonal antibody 17-1A (gamma 2a, kappa) recognizes a tumor-associated antigen expressed on human gastrointestinal malignancies and has been used in Phase I and II clinical trials. Chimeric genetic constructs have been produced using 17-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f5337d8227d026d9defcd4ae2b3e4818
https://pubmed.ncbi.nlm.nih.gov/3361351
https://pubmed.ncbi.nlm.nih.gov/3361351