Zobrazeno 1 - 10
of 39
pro vyhledávání: '"P. E. Clements"'
Autor:
Diana E. Clements, Tosin Olaiya, Cindy Burman, Oscar Herrera-Restrepo, Woo-Yun Sohn, Temi Folaranmi, Victoria Abbing-Karahagopian, Gary S. Marshall, James H. Conway
Publikováno v:
Expert Review of Vaccines, Vol 23, Iss 1, Pp 845-861 (2024)
Introduction In 2005, the United States Advisory Committee on Immunization Practices (ACIP) recommended routine vaccination against invasive meningococcal disease (IMD) caused by serogroups A, C, W, and Y (MenACWY) for all 11–12-year-olds, as well
Externí odkaz:
https://doaj.org/article/490b02a481534543b74c5c84421d4ca2
Autor:
Natalie J. Castell, Celina M. Abreu, Erin N. Shirk, Suzanne E. Queen, Joseph L. Mankowski, Janice E. Clements, Rebecca T. Veenhuis
Publikováno v:
Cell Reports, Vol 43, Iss 10, Pp 114833- (2024)
Summary: Viral encephalitis is a growing public health threat with limited diagnostic and treatment options. Simian immunodeficiency virus (SIV)-infected macaques are an established model for human immunodeficiency virus (HIV), and approximately 60%
Externí odkaz:
https://doaj.org/article/af5a772730034531ac835234f852a782
Autor:
Oscar Herrera-Restrepo, Yuting Kuang, John D’Angelo, Rafik Bekkat-Berkani, Diana E. Clements, Jennifer Uyei
Publikováno v:
Infectious Diseases and Therapy, Vol 12, Iss 5, Pp 1265-1282 (2023)
Abstract We conducted a targeted literature review to understand the determinants of meningococcal serogroups A, C, W, and Y (MenACWY) and meningococcal serogroup B (MenB) vaccination coverage and adherence to vaccination schedules in the USA, and to
Externí odkaz:
https://doaj.org/article/06c5b7c099344189b96e89e9277346ad
Publikováno v:
Infectious Diseases and Therapy, Vol 12, Iss 4, Pp 1019-1027 (2023)
Abstract Patients with functional or anatomic asplenia, including sickle cell anemia; complement component deficiency; or human immunodeficiency virus (HIV) infection have a significantly increased risk of developing meningococcal disease. The Adviso
Externí odkaz:
https://doaj.org/article/6186bc8540ee42e398be949e2b2ed386
Publikováno v:
JBMR Plus, Vol 7, Iss 3, Pp n/a-n/a (2023)
ABSTRACT Breast cancer has a high predilection for spreading to bone with approximately 70% of patients who succumb to disease harboring bone disseminated tumor cells. Despite this high prevalence, treatments for bone metastatic breast cancer predomi
Externí odkaz:
https://doaj.org/article/6305b471601144e089d587ca3c27c83e
Autor:
Vera M. Todd, Lawrence A. Vecchi, Miranda E. Clements, Katherine P. Snow, Cayla D. Ontko, Lauren Himmel, Christopher Pinelli, Marjan Rafat, Rachelle W. Johnson
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-18 (2021)
Todd et al employ a PyMT-driven spontaneous murine mammary carcinoma model with mammary-specific deletion of hypoxia inducible factors Hif1α, Hif2α, or von Hippel-Lindau factor to further investigate their role in bone and lung metastasis. They fin
Externí odkaz:
https://doaj.org/article/975f1c09009840709de77452a7dc73cb
Autor:
Kristen E. Clements, Emily M. Schleicher, Tanay Thakar, Anastasia Hale, Ashna Dhoonmoon, Nathanial J. Tolman, Anchal Sharma, Xinwen Liang, Yuka Imamura Kawasawa, Claudia M. Nicolae, Hong-Gang Wang, Subhajyoti De, George-Lucian Moldovan
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Mutations in the homologous recombination proteins BRCA1 and BRCA2 can sensitize cells to treatment with inhibitors of poly-ADP-ribose polymerase 1 (PARPi), but resistance to the treatment can occur. Here the authors by genome-wide CRISPR knockout an
Externí odkaz:
https://doaj.org/article/bbee1b004cdc4bdebae2ddc9b6d5a3f3
Autor:
Tanay Thakar, Wendy Leung, Claudia M. Nicolae, Kristen E. Clements, Binghui Shen, Anja-Katrin Bielinsky, George-Lucian Moldovan
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
PCNA is essential for DNA replication and cellular proliferation. Here, the authors reveal that PCNA ubiquitination protects stalled replication forks from DNA2-mediated degradation via regulation of Okazaki fragment maturation and chromatin assembly
Externí odkaz:
https://doaj.org/article/83d73c42ce554d03b39eb16def8e823b
Autor:
Kassandra L. Carpio, Jill K. Thompson, Steven G. Widen, Jennifer K. Smith, Terry L. Juelich, David E. Clements, Alexander N. Freiberg, Alan D. T. Barrett
Publikováno v:
Viruses, Vol 15, Iss 2, p 281 (2023)
The genetic diversities of mammalian tick-borne flaviviruses are poorly understood. We used next-generation sequencing (NGS) to deep sequence different viruses and strains belonging to this group of flaviviruses, including Central European tick-borne
Externí odkaz:
https://doaj.org/article/f0bc9e970712431cb02569b6b9fee9c6
Autor:
Chih-Yun Lai, Albert To, Teri Ann S. Wong, Michael M. Lieberman, David E. Clements, James T. Senda, Aquena H. Ball, Laurent Pessaint, Hanne Andersen, Wakako Furuyama, Andrea Marzi, Oreola Donini, Axel T. Lehrer
Publikováno v:
Vaccine: X, Vol 9, Iss , Pp 100126- (2021)
The speed at which several COVID-19 vaccines went from conception to receiving FDA and EMA approval for emergency use is an achievement unrivaled in the history of vaccine development. Mass vaccination efforts using the highly effective vaccines are
Externí odkaz:
https://doaj.org/article/4899da1012804294873b875b8874ede5