Zobrazeno 1 - 10
of 148
pro vyhledávání: '"P. Douaud"'
The effects of genetic and modifiable risk factors on brain regions vulnerable to ageing and disease
Autor:
Jordi Manuello, Joosung Min, Paul McCarthy, Fidel Alfaro-Almagro, Soojin Lee, Stephen Smith, Lloyd T. Elliott, Anderson M. Winkler, Gwenaëlle Douaud
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract We have previously identified a network of higher-order brain regions particularly vulnerable to the ageing process, schizophrenia and Alzheimer’s disease. However, it remains unknown what the genetic influences on this fragile brain netwo
Externí odkaz:
https://doaj.org/article/f392aeae61674a35ae9159c1f37dfbd2
Autor:
Soojin Lee, Janine D. Bijsterbosch, Fidel Alfaro Almagro, Lloyd Elliott, Paul McCarthy, Bernd Taschler, Roser Sala-Llonch, Christian F. Beckmann, Eugene P. Duff, Stephen M. Smith, Gwenaëlle Douaud
Publikováno v:
NeuroImage, Vol 265, Iss , Pp 119779- (2023)
Resting-state fMRI studies have shown that multiple functional networks, which consist of distributed brain regions that share synchronised spontaneous activity, co-exist in the brain. As these resting-state networks (RSNs) have been thought to refle
Externí odkaz:
https://doaj.org/article/094ea34459044324aa78533eeb8a29d9
Autor:
Matthew J. Rowland, Payashi Garry, Martyn Ezra, Rufus Corkill, Ian Baker, Peter Jezzard, Jon Westbrook, Gwenaëlle Douaud, Kyle T. S. Pattinson
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The first 72 h following aneurysm rupture play a key role in determining clinical and cognitive outcomes after subarachnoid haemorrhage (SAH). Yet, very little is known about the impact of so called “early brain injury” on patents with c
Externí odkaz:
https://doaj.org/article/6c85b39ff6f34420a0acc33093394972
Autor:
Christel Gudberg, Remi Stevelink, Gwenaëlle Douaud, Katharina Wulff, Alberto Lazari, Melanie K. Fleming, Heidi Johansen-Berg
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Sleep plays a key role in supporting brain function and resilience to brain decline. It is well known that sleep changes substantially with aging and that aging is associated with deterioration of brain structure. In this study, we sought to characte
Externí odkaz:
https://doaj.org/article/f11440f1140f4972aedbab4d4a2eadba
Akademický článek
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Autor:
Eugene Duff, Fernando Zelaya, Fidel Alfaro Almagro, Karla L Miller, Naomi Martin, Thomas E Nichols, Bernd Taschler, Ludovica Griffanti, Christoph Arthofer, Gwenaëlle Douaud, Chaoyue Wang, Thomas W Okell, Richard A I Bethlehem, Klaus Eickel, Matthias Günther, David K Menon, Guy Williams, Bethany Facer, David J Lythgoe, Flavio Dell'Acqua, Greta K Wood, Steven C R Williams, Gavin Houston, Simon S Keller, Catherine Holden, Monika Hartmann, Lily George, Gerome Breen, Benedict D Michael, Peter Jezzard, Stephen M Smith, Edward T Bullmore, COVID-CNS Consortium
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0273704 (2022)
IntroductionMagnetic resonance imaging (MRI) of the brain could be a key diagnostic and research tool for understanding the neuropsychiatric complications of COVID-19. For maximum impact, multi-modal MRI protocols will be needed to measure the effect
Externí odkaz:
https://doaj.org/article/189e8334c40c4c98a9b04233f14fd0a1
Autor:
Shaun Warrington, Katherine L. Bryant, Alexandr A. Khrapitchev, Jerome Sallet, Marina Charquero-Ballester, Gwenaëlle Douaud, Saad Jbabdi, Rogier B. Mars, Stamatios N. Sotiropoulos
Publikováno v:
NeuroImage, Vol 217, Iss , Pp 116923- (2020)
We present a new software package with a library of standardised tractography protocols devised for the robust automated extraction of white matter tracts both in the human and the macaque brain. Using in vivo data from the Human Connectome Project (
Externí odkaz:
https://doaj.org/article/f5e967abca364e34918c9aa7d55a182e
Autor:
Stephen M Smith, Lloyd T Elliott, Fidel Alfaro-Almagro, Paul McCarthy, Thomas E Nichols, Gwenaëlle Douaud, Karla L Miller
Publikováno v:
eLife, Vol 9 (2020)
Brain imaging can be used to study how individuals’ brains are aging, compared against population norms. This can inform on aspects of brain health; for example, smoking and blood pressure can be seen to accelerate brain aging. Typically, a single
Externí odkaz:
https://doaj.org/article/aec871cafe71411183c2a93996f14086
Autor:
Jean-Francois Mangin, Denis Rivière, Edouard Duchesnay, Yann Cointepas, Véronique Gaura, Christophe Verny, Philippe Damier, Pierre Krystkowiak, Anne-Catherine Bachoud-Lévi, Philippe Hantraye, Philippe Remy, Gwenaëlle Douaud
Publikováno v:
NeuroImage: Clinical, Vol 26, Iss , Pp - (2020)
Huntington's disease (HD) is an inherited, autosomal dominant disorder that is characteristically thought of as a degenerative disorder. Despite cellular and molecular grounds suggesting HD could also impact normal development, there has been scarce
Externí odkaz:
https://doaj.org/article/aa8f8d6e4cc84a6aaa449c2ac2538ff0
Autor:
Chris Patrick Pflanz, Marina Charquero-Ballester, D.S. Adnan Majid, Anderson M. Winkler, Emmanuel Vallée, Adam R. Aron, Mark Jenkinson, Gwenaëlle Douaud
Publikováno v:
NeuroImage: Clinical, Vol 25, Iss , Pp - (2020)
Objective: To determine whether brain imaging markers of tissue microstructure can detect the effect of disease progression across the preclinical stages of Huntington's disease. Methods: Longitudinal microstructural changes in diffusion imaging metr
Externí odkaz:
https://doaj.org/article/e0bd75be8f75461f84db2d082482b68d