Výsledky vyhledávání - "P. Dominic Reynolds"

Titanium Dioxide Nanoparticles Induce DNA Damage in Peripheral Blood Lymphocytes from Polyposis coli, Colon Cancer Patients and Healthy Individuals: An Ex Vivo/In Vitro Study

Autor: P. Dominic Reynolds, Justin P Davies, Ritesh K Shukla, Vyom Sharma, Mojgan Najafzadeh, Diana Anderson, Alok Dhawan, Malgorzata Kurzawa-Zegota

Publikováno v: Journal of Nanoscience and Nanotechnology. 17:9274-9285

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5958057dcfb5e2a63e7d44e417798133
https://doi.org/10.1166/jnn.2017.14691

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In vitro sensitivities to UVA of lymphocytes from patients with colon and melanoma cancers and precancerous states in the micronucleus and the Comet assays

Autor: Justin B. Davies, Mojgan Najafzadeh, Adolf Baumgartner, Diana Anderson, Rajendran C. Gopalan, P. Dominic Reynolds, Andrew Wright

Publikováno v: Mutagenesis. 27:351-357

To use lymphocytes as surrogate cells to investigate their in vitro sensitivities to ultraviolet (UV) treatment in different cancers and precancerous states by comparison with lymphocytes from healthy control individuals was the main aim of this rese

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5592b735cd1137f472d326f8a8230ed
https://doi.org/10.1093/mutage/ger087

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Flavonoids inhibit the genotoxicity of hydrogen peroxide (H2O2) and of the food mutagen 2-amino-3-methylimadazo[4,5-f]-quinoline (IQ) in lymphocytes from patients with inflammatory bowel disease (IBD)

Autor: P. Dominic Reynolds, Mojgan Najafzadeh, Diana Anderson, Adolf Baumgartner

Publikováno v: Mutagenesis. 24:405-411

Inflammatory bowel disease (IBD) including Crohn's disease (CD) and ulcerative colitis (UC) is a chronic inflammatory gastrointestinal autoimmune condition with an inappropriate immune response. We investigated DNA damage induced in vitro in lymphocy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eb1c8ffd168bfd7b060bfd616963d73
https://doi.org/10.1093/mutage/gep016

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Ethnicity, Gender, and Socioeconomic Status as Risk Factors for Esophagitis and Barrett's Esophagus

Autor: Paul Moayyedi, Brian T. Cooper, David Forman, Alexander C. Ford, P. Dominic Reynolds

Publikováno v: American Journal of Epidemiology. 162:454-460

Barrett’s esophagus is thought to be a disease occurring predominantly in White Caucasian males of higher socioeconomic status. There are no published studies simultaneously examining risk of Barrett’s esophagus according to ethnicity, gender, an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdd09242a0c7e63c824dd5f353c15b87
https://doi.org/10.1093/aje/kwi218

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Sensitivity and specificity of the empirical lymphocyte genome sensitivity (LGS) assay: implications for improving cancer diagnostics

Autor: P. Dominic Reynolds, Andrew J. Scally, Morgan Denyer, Andrew Wright, Mojgan Najafzadeh, Diana Anderson, David T. Sharpe, Stephen T. Britland, Rajendran C. Gopalan, Nader Ghaderi, Shariff Al-Ghazal, Justin Davies, Badie K. Jacobs

Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 28(10)

Lymphocyte responses from 208 individuals: 20 with melanoma, 34 with colon cancer, and 4 with lung cancer (58), 18 with suspected melanoma, 28 with polyposis, and 10 with COPD (56), and 94 healthy volunteers were examined. The natural logarithm of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f76565a205c6e967e32ca0ab39885cc6
https://pubmed.ncbi.nlm.nih.gov/25063845

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The Effect of Flavonoids in Soybean Products in Lymphocytes from IBD and Colon Cancer Patients After Treatment with Food Mutagens and Hydrogen Peroxide

Autor: Adolf Baumgartner, P. Dominic Reynolds, Malgorzata Kurzawa-Zegota, Mojgan Najafzadeh, Justin B. Davies, Diana Anderson

Publikováno v: Soybean and Health

Mojgan Najafzadeh1, Malgorzata Kurzawa-Zegota1, Adolf Baumgartner1,3, P. Dominic Reynolds2, Justin B. Davies2 and Diana Anderson1 1School of Life Sciences, Genetic and Reproductive Toxicology Group, Division of Biomedical Sciences, University of Brad

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::324bd8c2f44c1b91c6e4da7bf2194ea2
http://www.intechopen.com/articles/show/title/the-effect-of-flavonoids-in-soybean-products-in-lymphocytes-from-ibd-and-colon-cancer-patients-after

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Chaga mushroom extract inhibits oxidative DNA damage in lymphocytes of patients with inflammatory bowel disease

Autor: David Jerwood, Adolf Baumgartner, P. Dominic Reynolds, Mojgan Najafzadeh, Diana Anderson

Publikováno v: Scopus-Elsevier
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Inflammatory Bowel Disease (IBD) is partly caused by oxidative stress from free radicals and reduced antioxidant levels. Using hydrogen peroxide to induce oxidative stress in vitro in peripheral lymphocytes we investigated the induction of DNA damage

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da281db21c51c9eed8daed9bbf222206
http://www.scopus.com/inward/record.url?eid=2-s2.0-57349117095&partnerID=MN8TOARS

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