Zobrazeno 1 - 10
of 92
pro vyhledávání: '"P. D. Davies"'
Publikováno v:
JTO Clinical and Research Reports, Vol 5, Iss 7, Pp 100673- (2024)
Repotrectinib, licensed in November 2023, is a novel ROS1 tyrosine kinase inhibitor (TKI) with activity against G2032R, the most common resistance mutation to prior generations of ROS1 TKIs. Here, we report a case of a patient who was heavily pretrea
Externí odkaz:
https://doaj.org/article/7431ea6377e4481c94bd50a8012202bb
Autor:
Lisa J. Burklund, Carolyn D. Davies, Andrea Niles, Jared B. Torre, Lily Brown, Meghan Vinograd, Matthew D. Lieberman, Michelle G. Craske
Publikováno v:
Frontiers in Psychology, Vol 15 (2024)
IntroductionA significant portion of individuals exposed to combat-related trauma will develop posttraumatic stress disorder (PTSD), a severe, debilitating disorder with adverse impacts on both mental and physical functioning. Current treatments are
Externí odkaz:
https://doaj.org/article/19e6f71a16cb48c8af5bf56f530a5ce0
Autor:
S. Obaro, F. Hassan-Hanga, N. Medugu, R. Olaosebikan, G. Olanipekun, B. Jibir, S. Gambo, Theresa Ajose, Carissa Duru, B. Ebruke, H. D. Davies
Publikováno v:
BMC Infectious Diseases, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background Diagnosis of bacterial meningitis remains a challenge in most developing countries due to low yield from bacterial culture, widespread use of non-prescription antibiotics, and weak microbiology laboratories. The objective of this
Externí odkaz:
https://doaj.org/article/bdcdd798a3004bc0b96422142597dea0
Autor:
Tejas Patil, MD, Alyse Staley, MS, Yunan Nie, MD, Mandy Sakamoto, MD, Margaret Stalker, MD, James M. Jurica, MD, MBA, Kenna Koehler, BA, Amanda Cass, PharmD, Halle Kuykendall, BA, Emily Schmitt, MS, Emma Filar, BA, Evelina Reventaite, MS, Kurt D. Davies, PhD, Hala Nijmeh, PhD, Mary Haag, PhD, Benjamin A. Yoder, PharmD, Paul A. Bunn, MD, Erin L. Schenk, MD, PhD, Dara L. Aisner, MD, PhD, Wade T. Iams, MD, Melina E. Marmarelis, MD, D. Ross Camidge, MD, PhD
Publikováno v:
JTO Clinical and Research Reports, Vol 5, Iss 2, Pp 100637- (2024)
Introduction: Acquired MET gene amplification, MET exon 14 skip mutations, or MET fusions can emerge as resistance mechanisms to tyrosine kinase inhibitors (TKIs) in patients with lung cancer. The efficacy and safety of combining MET TKIs (such as cr
Externí odkaz:
https://doaj.org/article/63d7bcf67c604305b7273bb565a9b37b
Autor:
Katherine Priest, Anh Le, Amanuail Gebregzabheir, Hala Nijmeh, Gregory B. Reis, Melanie Mandell, Kurtis D. Davies, Carolyn Lawrence, Emily O’Donnell, Robert C. Doebele, Liming Bao, Dara L. Aisner, Erin L. Schenk
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-7 (2023)
Abstract Patients with metastatic NSCLC bearing a ROS1 gene fusion usually experience prolonged disease control with ROS1-targeting tyrosine kinase inhibitors (TKI), but significant clinical heterogeneity exists in part due to the presence of co-occu
Externí odkaz:
https://doaj.org/article/d06abc523d8e46278ad3f301b11a80b8
Autor:
Harriet Tucker, Karim Brohi, Joachim Tan, Christopher Aylwin, Roger Bloomer, Rebecca Cardigan, Ross Davenport, Edward D. Davies, Phillip Godfrey, Rachel Hawes, Richard Lyon, Josephine McCullagh, Simon Stanworth, Julian Thompson, James Uprichard, Simon Walsh, Anne Weaver, Laura Green
Publikováno v:
Critical Care, Vol 27, Iss 1, Pp 1-10 (2023)
Abstract Background In-hospital acute resuscitation in trauma has evolved toward early and balanced transfusion resuscitation with red blood cells (RBC) and plasma being transfused in equal ratios. Being able to deliver this ratio in prehospital envi
Externí odkaz:
https://doaj.org/article/04cfc33611374701a348a23d869a004b
Autor:
Sean J. Iwamoto, Justine Defreyne, Christodoulos Kaoutzanis, Robert D. Davies, Kerrie L. Moreau, Micol S. Rothman
Publikováno v:
Therapeutic Advances in Endocrinology and Metabolism, Vol 14 (2023)
As the transgender and gender diverse (TGD) population ages, more transfeminine and transmasculine individuals present to clinic to initiate or continue their gender-affirming care at older ages. Currently available guidelines on gender-affirming car
Externí odkaz:
https://doaj.org/article/ed218aef74434ae0af85d487c6d79513
Autor:
Luke A. Baker, Daniel S. March, Thomas J. Wilkinson, Roseanne E. Billany, Nicolette C. Bishop, Ellen M. Castle, Joseph Chilcot, Mark D. Davies, Matthew P. M. Graham-Brown, Sharlene A. Greenwood, Naushad A. Junglee, Archontissa M. Kanavaki, Courtney J. Lightfoot, Jamie H. Macdonald, Gabriella M. K. Rossetti, Alice C. Smith, James O. Burton
Publikováno v:
BMC Nephrology, Vol 23, Iss 1, Pp 1-36 (2022)
Externí odkaz:
https://doaj.org/article/ad65ebfd7101412b84c5cc635711c366
Autor:
T. L. Peters, T. Patil, A. T. Le, K. D. Davies, P. M. Brzeskiewicz, H. Nijmeh, L. Bao, D. R. Camidge, D. L. Aisner, R. C. Doebele
Publikováno v:
npj Precision Oncology, Vol 5, Iss 1, Pp 1-6 (2021)
Abstract EGFR mutant non-small cell lung cancer patients' disease demonstrates remarkable responses to EGFR-targeted therapy, but inevitably they succumb to acquired resistance, which can be complex and difficult to treat. Analyzing acquired resistan
Externí odkaz:
https://doaj.org/article/a60d71a2c6b74878abf284abc023a3a1
Publikováno v:
Canadian Journal of Respiratory Therapy, Vol 57 (2021)
Introduction Accumulation of secretions in an endotracheal tube can increase the resistance to flow resulting in an increased patient work of breathing when the patient is interacting with the ventilator. Retained secretions can also serve as an inf
Externí odkaz:
https://doaj.org/article/ec6ef6184ddb42c2b94c99b813e3bd80