Zobrazeno 1 - 10
of 51
pro vyhledávání: '"P. D. Currie"'
Autor:
A. J. Wood, C. H. Lin, M. Li, K. Nishtala, S. Alaei, F. Rossello, C. Sonntag, L. Hersey, L. B. Miles, C. Krisp, S. Dudczig, A. J. Fulcher, S. Gibertini, P. J. Conroy, A. Siegel, M. Mora, P. Jusuf, N. H. Packer, P. D. Currie
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
FKRP mutations cause muscular dystrophies with varied clinical presentations. The target of FKRP is α-dystroglycan, but here the authors show that FKRP also directs sialylation of fibronectin, a process that is essential for recruitment o collagen t
Externí odkaz:
https://doaj.org/article/5e6f8208fa384dfab7d8162c046eec48
Publikováno v:
Environments, Vol 11, Iss 9, p 188 (2024)
Neurodevelopmental disorders (NDDs) encompass a range of conditions that begin during the developmental stage and cause deficits that lead to disruptions in normal functioning. One class of chemicals that is of increasing concern for neurodevelopment
Externí odkaz:
https://doaj.org/article/865b4f311f1d4e3e84f4c84df70eb730
Autor:
Ashley T. Sendell-Price, Frank J. Tulenko, Mats Pettersson, Du Kang, Margo Montandon, Sylke Winkler, Kathleen Kulb, Gavin P. Naylor, Adam Phillippy, Olivier Fedrigo, Jacquelyn Mountcastle, Jennifer R. Balacco, Amalia Dutra, Rebecca E. Dale, Bettina Haase, Erich D. Jarvis, Gene Myers, Shawn M. Burgess, Peter D. Currie, Leif Andersson, Manfred Schartl
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Sharks occupy diverse ecological niches and play critical roles in marine ecosystems, often acting as apex predators. They are considered a slow-evolving lineage and have been suggested to exhibit exceptionally low cancer rates. These two fe
Externí odkaz:
https://doaj.org/article/697d70ec965d44079d0c1fc4031212cc
Autor:
Muthukumar Karuppasamy, Katherine G. English, Clarissa A. Henry, M. Chiara Manzini, John M. Parant, Melissa A. Wright, Avnika A. Ruparelia, Peter D. Currie, Vandana A. Gupta, James J. Dowling, Lisa Maves, Matthew S. Alexander
Publikováno v:
Disease Models & Mechanisms, Vol 17, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/4f13b14e9c2a4d84a3835d5d9afdf89d
Autor:
Haixing Wang, Sien Lin, Lu Feng, Baozhen Huang, Xuan Lu, Zhengmeng Yang, Zhaowei Jiang, Yu‐Cong Li, Xiaoting Zhang, Ming Wang, Bin Wang, Lingchi Kong, Qi Pan, Shanshan Bai, Yuan Li, Yongkang Yang, Wayne Yuk Wai Lee, Peter D. Currie, Changshuang Lin, Yanfu Jiang, Juyu Chen, Micky D. Tortorella, Hongyi Li, Gang Li
Publikováno v:
Advanced Science, Vol 10, Iss 28, Pp n/a-n/a (2023)
Abstract Studies in recent years have highlighted an elaborate crosstalk between T cells and bone cells, suggesting that T cells may be alternative therapeutic targets for the maintenance of bone homeostasis. Here, it is reported that systemic admini
Externí odkaz:
https://doaj.org/article/5c3ffbda92f844ef80a22b82ae5f7cf2
Autor:
Marketa Kaucka, Alberto Joven Araus, Marketa Tesarova, Joshua D. Currie, Johan Boström, Michaela Kavkova, Julian Petersen, Zeyu Yao, Anass Bouchnita, Andreas Hellander, Tomas Zikmund, Ahmed Elewa, Phillip T. Newton, Ji-Feng Fei, Andrei S. Chagin, Kaj Fried, Elly M. Tanaka, Jozef Kaiser, András Simon, Igor Adameyko
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Normal limb development relies on synchronized formation of cartilage and bone. Here, the authors show that in salamander limb regeneration these processes are decoupled: ossification occurs after the final size of regenerating cartilage is reached,
Externí odkaz:
https://doaj.org/article/31087e8d6b4b4eacb845ec3be1507dcc
Autor:
Inken G. Huttner, Celine F. Santiago, Arie Jacoby, Delfine Cheng, Gunjan Trivedi, Stephen Cull, Jasmina Cvetkovska, Renee Chand, Joachim Berger, Peter D. Currie, Kelly A. Smith, Diane Fatkin
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 10, Iss 10, p 408 (2023)
Dilated cardiomyopathy (DCM) is a common heart muscle disorder that frequently leads to heart failure, arrhythmias, and death. While DCM is often heritable, disease-causing mutations are identified in only ~30% of cases. In a forward genetic mutagene
Externí odkaz:
https://doaj.org/article/25a88d7c2438408e9bbcc8a2e84a4113
Publikováno v:
Journal of Ophthalmic & Vision Research, Vol 18, Iss 1, Pp 1-2 (2023)
Abstract Purpose: Mutations in TCP-1 ring complex (TRiC) have been associated with Leber Congenital Amaurosis (LCA). TRiC is involved in protein folding and has 8 essential subunits including CCT5. Herein, we studied the retina of TRiC mutant zebrafi
Externí odkaz:
https://doaj.org/article/34f710ccd5b2410989160822753044c3
Autor:
Camilo Riquelme-Guzmán, Stephanie L Tsai, Karen Carreon Paz, Congtin Nguyen, David Oriola, Maritta Schuez, Jan Brugués, Joshua D Currie, Tatiana Sandoval-Guzmán
Publikováno v:
eLife, Vol 11 (2022)
Early events during axolotl limb regeneration include an immune response and the formation of a wound epithelium. These events are linked to a clearance of damaged tissue prior to blastema formation and regeneration of the missing structures. Here, w
Externí odkaz:
https://doaj.org/article/d4b2a112d2ab4fe28ae5440bddc84f13
Publikováno v:
Heliyon, Vol 8, Iss 10, Pp e11093- (2022)
Acute myeloid leukemia (AML) is one of the most prevalent and acute blood cancers with a poor prognosis and low overall survival rate, especially in the elderly. Although several new AML markers and drug targets have been recently identified, the rat
Externí odkaz:
https://doaj.org/article/bed663c6c63d4e1f8845f868f2c24ad2