Zobrazeno 1 - 10
of 89
pro vyhledávání: '"P. D. Byrne"'
Autor:
Alessandro Mantovani, Fabiana Busti, Nicolò Borella, Enrico Scoccia, Barbara Pecoraro, Elena Sani, Riccardo Morandin, Alessandro Csermely, Daniele Piasentin, Elisabetta Grespan, Annalisa Castagna, Josh Bilson, Christopher D. Byrne, Luca Valenti, Domenico Girelli, Giovanni Targher
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-12 (2024)
Abstract Background The effect of plasma hepcidin concentrations on the long-term risk of developing adverse cardiovascular outcomes in people with type 2 diabetes mellitus (T2DM) is unclear. Methods We followed for a median of 55.6 months 213 outpat
Externí odkaz:
https://doaj.org/article/6fbad8d37d6943448aab47642fff4959
Autor:
Lumin Yang, Yafei Zhang, Xiaodan Hong, Ke Zhang, Bingyan Liu, Peixin Zhang, Qianqian Tang, Jian Yu, Xiao-Zhi Jin, Xin-Zhe Jin, Ni Zhang, Giovanni Targher, Christopher D. Byrne, Zhenhua Zhang, Ming-Hua Zheng, Jinsong Zhang
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract Background APRI and FIB-4 scores are used to exclude clinically significant fibrosis (defined as stage ≥ F2) in patients with chronic viral hepatitis. However, the cut-offs for these scores (generated by Youden indices) vary between differ
Externí odkaz:
https://doaj.org/article/afb52d6865d1493ca2debc3c64d5ac07
Autor:
In Young Cho, Yoosoo Chang, Eunju Sung, Boyoung Park, Jae-Heon Kang, Hocheol Shin, Sarah H. Wild, Christopher D. Byrne, Seungho Ryu
Publikováno v:
Cancer & Metabolism, Vol 12, Iss 1, Pp 1-10 (2024)
Abstract Background The effects of glycemic status and insulin resistance on lung cancer remain unclear. We investigated the associations between both glycemic status and insulin resistance, and lung cancer mortality, in a young and middle-aged popul
Externí odkaz:
https://doaj.org/article/6794894e5ee94970b0e453079c193ba1
Autor:
Qateeb Khan, MD, Breann Bowar, MD, Bryn Myers, MD, Fatima Kenjar, BS, James D. Byrne, MD, PhD, Jordan Gainey, MD
Publikováno v:
Advances in Radiation Oncology, Vol 9, Iss 5, Pp 101452- (2024)
Purpose: An effective didactic curriculum is a cornerstone for a successful residency program, as it is the basis upon which residents acquire the necessary knowledge and perspective to provide high-quality, evidence-based care. Here we describe our
Externí odkaz:
https://doaj.org/article/ca4f7ff8e24340afbe06d591065083fc
Publikováno v:
Biomolecules, Vol 14, Iss 7, p 841 (2024)
Affecting approximately 25% of the global population, steatotic liver disease (SLD) poses a significant health concern. SLD ranges from simple steatosis to metabolic dysfunction-associated steatohepatitis and fibrosis with a risk of severe liver comp
Externí odkaz:
https://doaj.org/article/a431fc7bb47440c58f9ecf5cb82772ad
Autor:
Jianling Bi, Emily Witt, Megan K. McGovern, Arielle B. Cafi, Lauren L. Rosenstock, Anna B. Pearson, Timothy J. Brown, Thomas B. Karasic, Lucas C. Absler, Srija Machkanti, Hannah Boyce, David Gallo, Sarah L. Becker, Keiko Ishida, Joshua Jenkins, Alison Hayward, Alexandra Scheiflinger, Kellie L. Bodeker, Ritesh Kumar, Scott K. Shaw, Salma K. Jabbour, Vitor A. Lira, Michael D. Henry, Michael S. Tift, Leo E. Otterbein, Giovanni Traverso, James D. Byrne
Publikováno v:
Advanced Science, Vol 11, Iss 9, Pp n/a-n/a (2024)
Abstract Modulation of autophagy, specifically its inhibition, stands to transform the capacity to effectively treat a broad range of cancers. However, the clinical efficacy of autophagy inhibitors has been inconsistent. To delineate clinical and epi
Externí odkaz:
https://doaj.org/article/f858b9587aa7486a8b205a415ae94226
Autor:
Xiao‐Dong Zhou, Qin‐Fen Chen, Giovanni Targher, Christopher D. Byrne, Michael D. Shapiro, Na Tian, Tie Xiao, Ki‐Chul Sung, Gregory Y. H. Lip, Ming‐Hua Zheng
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 3 (2024)
Background Systemic chronic inflammation plays a role in the pathophysiology of both heart failure with preserved ejection fraction (HFpEF) and metabolic dysfunction‐associated fatty liver disease. This study aimed to investigate whether serum hs
Externí odkaz:
https://doaj.org/article/30f5992e2cd34bafa4b6c321e0047d4c
Autor:
Qateeb Khan, Bryn Myers, Breann Bowar, Maryam Khan, Henry Mullaney, Jordan Gainey, Robert Schneider, Laila Dahmoush, Kenneth G. Nepple, James D. Byrne
Publikováno v:
Frontiers in Oncology, Vol 13 (2024)
BackgroundPeritoneal carcinomatosis is a particularly rare presentation of prostate cancer. Here we report a rare clinical case of surgically identified peritoneal carcinomatosis at the time of a planned robotic prostatectomy in a patient with a hist
Externí odkaz:
https://doaj.org/article/078a7c6771d74284ba0c16f16f1e3ae8
Autor:
Dan-Qin Sun, Fuqiang Yuan, Meng-Zhu Fu, Meng-Yang Zhong, Shi-Liang Zhang, Yan Lu, Giovanni Targher, Christopher D. Byrne, Ming-Hua Zheng, Wei-Jie Yuan
Publikováno v:
Molecular Metabolism, Vol 79, Iss , Pp 101841- (2024)
Objective: Activation of farnesoid X receptor (FXR), a bile acid nuclear receptor, may be implicated in the pathophysiology of diabetic nephropathy. We explored a possible role for FXR activation in preventing renal fibrosis in high fat diet (HFD)-fe
Externí odkaz:
https://doaj.org/article/f7bdadc31be8433692c488c59c9f0254
Autor:
Mary E. Rinella, Jeffrey V. Lazarus, Vlad Ratziu, Sven M. Francque, Arun J. Sanyal, Fasiha Kanwal, Diana Romero, Manal F. Abdelmalek, Quentin M. Anstee, Juan Pablo Arab, Marco Arrese, Ramon Bataller, Ulrich Beuers, Jerome Boursier, Elisabetta Bugianesi, Christopher D. Byrne, Graciela E. Castro Narro, Abhijit Chowdhury, Helena Cortez-Pinto, Donna R. Cryer, Kenneth Cusi, Mohamed El-Kassas, Samuel Klein, Wayne Eskridge, Jiangao Fan, Samer Gawrieh, Cynthia D. Guy, Stephen A. Harrison, Seung Up Kim, Bart G. Koot, Marko Korenjak, Kris V. Kowdley, Florence Lacaille, Rohit Loomba, Robert Mitchell-Thain, Timothy R. Morgan, Elisabeth E. Powell, Michael Roden, Manuel Romero-Gómez, Marcelo Silva, Shivaram Prasad Singh, Silvia C. Sookoian, C. Wendy Spearman, Dina Tiniakos, Luca Valenti, Miriam B. Vos, Vincent Wai-Sun Wong, Stavra Xanthakos, Yusuf Yilmaz, Zobair Younossi, Ansley Hobbs, Marcela Villota-Rivas, Philip N. Newsome
Publikováno v:
Annals of Hepatology, Vol 29, Iss 1, Pp 101133- (2024)
The principal limitations of the terms NAFLD and NASH are the reliance on exclusionary confounder terms and the use of potentially stigmatising language. This study set out to determine if content experts and patient advocates were in favor of a chan
Externí odkaz:
https://doaj.org/article/f02c612b79da4aaa8837228f72393227