Reduced Rank Regression for Mixed Predictor and Response Variables

Autor: de Rooij, Mark, Cotugno, Lorenza, Siciliano, Roberta

In this paper, we propose the generalized mixed reduced rank regression method, GMR$^3$ for short. GMR$^3$ is a regression method for a mix of numeric, binary and ordinal response variables. The predictor variables can be a mix of binary, nominal, or

Externí odkaz: http://arxiv.org/abs/2405.19865

Early and late gut microbiota signatures of stroke in high salt-fed stroke-prone spontaneously hypertensive rats

Autor: Silvia Bencivenni, Sara Roggiani, Augusta Zannoni, Gabriele Conti, Marco Fabbrini, Maria Cotugno, Rosita Stanzione, Donatella Pietrangelo, Margherita Litterio, Maurizio Forte, Carla Letizia Busceti, Francesco Fornai, Massimo Volpe, Silvia Turroni, Patrizia Brigidi, Monica Forni, Speranza Rubattu, Federica D’Amico

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)

Abstract The high salt-fed stroke-prone spontaneously hypertensive rat (SHRSP) is a suitable tool to study the mechanisms underlying stroke pathogenesis. Salt intake modifies the gut microbiota (GM) in rats and humans and alterations of the GM have p

Externí odkaz: https://doaj.org/article/90c4a6fbb86c477f9c96d026967c9231

Rapid de-escalation of anti-MRSA therapy guided by S. aureus nares screening for patients with pneumonia: protocol of a randomized controlled trial (SNAP study)

Autor: Elda De Vita, Francesco Vladimiro Segala, Francesco Cavallin, Giacomo Guido, Luisa Frallonardo, Sergio Cotugno, Carmen Pellegrino, Francesco Di Gennaro, Annalisa Saracino

Publikováno v: Frontiers in Medicine, Vol 11 (2024)

IntroductionThe current Infectious Disease Society of America and American Thoracic Society (IDSA/ATS) guidelines recommend linezolid or vancomycin as an empiric treatment for methicillin-resistant Staphylococcus aureus (MRSA) pneumonia in hospitaliz

Externí odkaz: https://doaj.org/article/22f312645b5e4f0cadbfd2822ddf6a8a

A holistic evaluation of patients with chronic Hepatitis D virus (HDV) infection enrolled in the Italian PITER-B and delta cohort

Autor: Loreta A. Kondili, Giuseppina Brancaccio, Maria Elena Tosti, Barbara Coco, Maria Giovanna Quaranta, Vincenzo Messina, Alessia Ciancio, Filomena Morisco, Valentina Cossiga, Ernesto Claar, Valerio Rosato, Marianna Ciarallo, Irene Cacciola, Francesca Romana Ponziani, Lucia Cerrito, Roberta Coppola, Francesco Longobardi, Elisa Biliotti, Alessia Rianda, Francesco Barbaro, Nicola Coppola, Maria Stanzione, Francesco Barchiesi, Stefano Fagiuoli, Mauro Viganò, Marco Massari, Francesco Paolo Russo, Alberto Ferrarese, Diletta Laccabue, Vito Di Marco, Pierluigi Blanc, Aldo Marrone, Giulia Morsica, Alessandro Federico, Donatella Ieluzzi, Alba Rocco, Francesco Giuseppe Foschi, Alessandro Soria, Ivana Maida, Luchino Chessa, Michele Milella, Elena Rosselli Del Turco, Salvatore Madonia, Liliana Chemello, Ivan Gentile, Pierluigi Toniutto, Matteo Bassetti, Lorenzo Surace, Leonardo Baiocchi, Adriano Pellicelli, Adriano De Santis, Massimo Puoti, Elisabetta Degasperi, Grazia Anna Niro, Anna Linda Zignego, Antonio Craxi, Giovanni Raimondo, Teresa Antonia Santantonio, Maurizia Rossana Brunetto, Giovanni Battista Gaeta, Alessio Aghemo, Chiara Baiguera, Pier Maria Battezzati, Sara Battistella, Maria Grazia Bavetta, Costanza Bertoni, Carolina Boni, Paola Brambilla, Antonella Bray, Federica Briano, Enrico Carmenini, Francesco Castelli, Luisa Cavalletto, Federica Cerini, Luciana Chidichimo, Elisa Colella, Giuliana Cologni, Silvia Como, Romina Corsini, Chiara Costa, Rosa Cotugno, Silvia Cretella, Fernando De Angelis, Pasqualina De Leo, Giovanni Di Perri, Elisabetta Falbo, Luigina Ferrigno, Ezio Fornasiere, Daniela Francisci, Pietro Gatti, Pietro Lampertico, Ilaria Lenci, Anna Licata, Alfredo Marzano, Antonio Mastroianni, Cesare Mazzaro, Monica Monti, Gerardo Nardone, Laura Ambra Nicolini, Nicola Passigato, Maria Bruna Pasticci, Piera Pierotti, Biagio Pinchera, Teresa Pollicino, Carmen Porcu, Giulia Quartini, Gabriele Rancatore, Mario Romeo, Maria Grazia Rumi, Annalisa Saracino, Ornella Schioppa, Ilaria Serio, Roberta Soffredini, Xhimi Tata, Marco Tizzani, Matteo Tonnini, Carlo Torti, Daniela Valenti, Serena Zaltron, Alessia Zoncada

Publikováno v: International Journal of Infectious Diseases, Vol 146, Iss , Pp 107115- (2024)

Background and Aims: We aimed to characterize the epidemiologic and comorbidities profiles of patients with chronic Hepatitis D (CHD) followed in clinical practice in Italy and explored their interferon (IFN) eligibility. Methods: This was a cross-se

Externí odkaz: https://doaj.org/article/d176c063bea340bc95d90a2a253e2009

Molecular mechanisms of naringenin modulation of mitochondrial permeability transition acting on F1FO-ATPase and counteracting saline load-induced injury in SHRSP cerebral endothelial cells

Autor: Salvatore Nesci, Cristina Algieri, Matteo Antonio Tallarida, Rosita Stanzione, Saverio Marchi, Donatella Pietrangelo, Fabiana Trombetti, Luca D’Ambrosio, Maurizio Forte, Maria Cotugno, Ilaria Nunzi, Rachele Bigi, Loredana Maiuolo, Antonio De Nino, Paolo Pinton, Giovanni Romeo, Speranza Rubattu

Publikováno v: European Journal of Cell Biology, Vol 103, Iss 2, Pp 151398- (2024)

Naringenin (NRG) was characterized for its ability to counteract mitochondrial dysfunction which is linked to cardiovascular diseases. The F1FO-ATPase can act as a molecular target of NRG. The interaction of NRG with this enzyme can avoid the energy

Externí odkaz: https://doaj.org/article/fa6f92a0d76e4bf882977013dbb4485a