Electron heating and radiation in high aspect ratio sub-micron plasma generated by an ultrafast Bessel pulse within a solid dielectric

Autor: Ardaneh, Kazem, Giust, Remo, Charpin, Pierre-Jean, Morel, Benoit, Courvoisier, Francois

When propagating inside dielectrics, an ultrafast Bessel beam creates a high aspect-ratio cylinder of plasma with nanometric diameter that extends over several tens of micrometers to centimeters. We analyze the interaction between the intense ultrafa

Externí odkaz: http://arxiv.org/abs/2301.02408

Development of tuberculosis treatment decision algorithms in children below 5 years hospitalised with severe acute malnutrition in Zambia and Uganda: a prospective diagnostic cohort studyResearch in context

Autor: Chishala Chabala, Clémentine Roucher, Minh Huyen Ton Nu Nguyet, Esther Babirekere, Muleya Inambao, Gerald Businge, Chifunda Kapula, Perfect Shankalala, Bwendo Nduna, Veronica Mulenga, Stephen Graham, Eric Wobudeya, Maryline Bonnet, Olivier Marcy, Angeline Serre, Anne Badrichani, Manoa Razafimanantsoa, Julien Poublan, Aurélia Vessière, Estelle Occelli, Aurélie Beuscart, Aurélie Charpin, Gemma Habiyambere, Salomé Mesnier, Eric Balestre, Nicolas Koskas, Marc D'Elbée, Hélène Font, Manon Lounnas, Hélène Espérou, Sandrine Couffin-Cadiergues, Alexis Kuppers, Benjamin Hamze, Gerald Bright Businge, Faith Namulinda, Robert Sserunjogi, Rashidah Nassozi, Charlotte Barungi, Aanyu Hellen, Muwonge Doreen, Eva Kagoya, Serene Aciparu, Chemutai Sophia, Samuel Ntambi, Amir Wasswa, Juliet Nangozi, Chimuka Hambulo, Vincent Kapotwe, Marjory Ngambi, Kunda Kasakwa, Mirriam Kanyama, Uzima Chirwa, Kapula Chifunda, Gae Mundundu, Susan Zulu, Grace Nawakwi, Teddy Siasulingana, Diana Attan Himwaze, Jessy Chilonga, Maria Chimbini, Mutinta Chilanga, Daniel Chola, Eustace Mwango, Mwamba Pumbwe, Mwate Mwambazi, Barbara Halende, Wyclef Mumba, Endreen Mankunshe, Maureen Silavwe, Moses Chakopo, Roy Moono, Chalilwe Chungu, Kevin Zimba, Monica Kapasa, Khozya Zyambo

Publikováno v: EClinicalMedicine, Vol 73, Iss , Pp 102688- (2024)

Summary: Background: In children with severe acute malnutrition (SAM) tuberculosis is common, challenging to diagnose, and often fatal. We developed tuberculosis treatment decision algorithms (TDAs) for children under the age of 5 years with SAM. Met

Externí odkaz: https://doaj.org/article/d7386509a33b452a839f692f49dfcb3d

Integrated compact regulators of protein activity enable control of signaling pathways and genome-editing in vivo

Autor: Nik Franko, António José da Silva Santinha, Shuai Xue, Haijie Zhao, Ghislaine Charpin-El Hamri, Randall Jeffrey Platt, Ana Palma Teixeira, Martin Fussenegger

Publikováno v: Cell Discovery, Vol 10, Iss 1, Pp 1-14 (2024)

Abstract Viral proteases and clinically safe inhibitors were employed to build integrated compact regulators of protein activity (iCROP) for post-translational regulation of functional proteins by tunable proteolytic activity. In the absence of inhib

Externí odkaz: https://doaj.org/article/413f1a30bbc14f51b61cd5aba5f6d641

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Development and validation of an electronic daily control score for asthma (e-DASTHMA): a real-world direct patient data study

Autor: Bernardo Sousa-Pinto, PhD, Cristina Jácome, PhD, Ana Margarida Pereira, MD, Frederico S Regateiro, MD, Rute Almeida, PhD, Wienczyslawa Czarlewski, MD, Marek Kulus, ProfMD, Mohamed H Shamji, ProfMD, Louis-Philippe Boulet, ProfMD, Matteo Bonini, MD, Luisa Brussino, MD, G Walter Canonica, ProfMD, Alvaro A Cruz, MD, Bilun Gemicioglu, ProfMD, Tari Haahtela, ProfMD, Maciej Kupczyk, MD, Violeta Kvedariene, MD, Desirée Larenas-Linnemann, MD, Renaud Louis, ProfMD, Marek Niedoszytko, ProfMD, Nhân Pham-Thi, MD, Francesca Puggioni, MD, Jan Romantowski, MD, Joaquin Sastre, ProfMD, Nicola Scichilone, ProfMD, Luis Taborda-Barata, ProfMD, Maria Teresa Ventura, MD, Rafael José Vieira, MD, Ioana Agache, ProfMD, Anna Bedbrook, BSc, Karl C Bergmann, MD, Rita Amaral, PhD, Luís Filipe Azevedo, PhD, Sinthia Bosnic-Anticevich, ProfPhD, Guy Brusselle, ProfMD, Roland Buhl, ProfMD, Lorenzo Cecchi, MD, Denis Charpin, MD, Claudia Chaves Loureiro, MD, Frédéric de Blay, ProfMD, Stefano Del Giacco, ProfMD, Philippe Devillier, ProfMD, Ewa Jassem, ProfMD, Guy Joos, ProfMD, Marek Jutel, ProfMD, Ludger Klimek, MD, Piotr Kuna, ProfMD, Daniel Laune, PhD, Jorge Luna Pech, MD, Mika Makela, ProfMD, Mario Morais-Almeida, MD, Rachel Nadif, PhD, Hugo E Neffen, MD, Ken Ohta, ProfMD, Nikolaos G Papadopoulos, ProfMD, Alberto Papi, ProfMD, Benoit Pétré, MD, Oliver Pfaar, MD, Daniela Rivero Yeverino, MD, Carlos Robalo Cordeiro, ProfMD, Nicolas Roche, ProfMD, Ana Sá-Sousa, PhD, Boleslaw Samolinski, ProfMD, Aziz Sheikh, ProfMD, Charlotte Suppli Ulrik, ProfMD, Omar S Usmani, ProfMD, Arunas Valiulis, ProfMD, Olivier Vandenplas, ProfMD, Pedro Vieira-Marques, PhD, Arzu Yorgancioglu, ProfMD, Torsten Zuberbier, ProfMD, Josep M Anto, ProfMD, João A Fonseca, PhD, Jean Bousquet, ProfMD

Publikováno v: The Lancet: Digital Health, Vol 5, Iss 4, Pp e227-e238 (2023)

Summary: Background: Validated questionnaires are used to assess asthma control over the past 1–4 weeks from reporting. However, they do not adequately capture asthma control in patients with fluctuating symptoms. Using the Mobile Airways Sentinel

Externí odkaz: https://doaj.org/article/56dce9f1f5fa4cbca1e55bfb1691b095