Zobrazeno 1 - 10
of 1 469
pro vyhledávání: '"P. Carninci"'
Autor:
Ido Amit, Kristin Ardlie, Fabiana Arzuaga, Gordon Awandare, Gary Bader, Alexander Bernier, Piero Carninci, Stacey Donnelly, Roland Eils, Alistair R. R. Forrest, Henry T. Greely, Roderic Guigo, Nir Hacohen, Muzlifah Haniffa, Emily Sarah Kirby, Bartha Maria Knoppers, Arnold Kriegstein, Ed S. Lein, Sten Linnarsson, Partha P. Majumder, Miriam Merad, Kerstin Meyer, Musa M. Mhlanga, Garry Nolan, Ntobeko A. B. Ntusi, Dana Pe’er, Shyam Prabhakar, Maili Raven-Adams, Aviv Regev, Orit Rozenblatt-Rosen, Senjuti Saha, Andrea Saltzman, Alex K. Shalek, Jay W. Shin, Henk Stunnenberg, Sarah A. Teichmann, Timothy Tickle, Alexandra-Chloe Villani, Christine Wells, Barbara Wold, Huanming Yang, Xiaowei Zhuang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-7 (2024)
Abstract The Human Cell Atlas (HCA) is a global partnership “to create comprehensive reference maps of all human cells—the fundamental units of life – as a basis for both understanding human health and diagnosing, monitoring, and treating disea
Externí odkaz:
https://doaj.org/article/f71d8167c39a41c8a3df2a2b706d5aba
Autor:
Nejc Haberman, Holly Digby, Rupert Faraway, Rebecca Cheung, Anob M. Chakrabarti, Andrew M. Jobbins, Callum Parr, Kayoko Yasuzawa, Takeya Kasukawa, Chi Wai Yip, Masaki Kato, Hazuki Takahashi, Piero Carninci, Santiago Vernia, Jernej Ule, Christopher R. Sibley, Aida Martinez-Sanchez, Boris Lenhard
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-23 (2024)
Abstract The 3′ untranslated region (3′UTR) plays a crucial role in determining mRNA stability, localisation, translation and degradation. Cap analysis of gene expression (CAGE), a method for the detection of capped 5′ ends of mRNAs, additional
Externí odkaz:
https://doaj.org/article/ad037dcdd70a4cf1aefd83bb7b5773ce
Autor:
Kokoro Ozaki, Yukiko Yatsuka, Yoshinobu Oyazato, Atsushi Nishiyama, Kazuhiro R. Nitta, Yoshihito Kishita, Takuya Fushimi, Masaru Shimura, Shohei Noma, Yohei Sugiyama, Michihira Tagami, Moe Fukunaga, Hiroko Kinoshita, Tomoko Hirata, Wataru Suda, Yasuhiro Murakawa, Piero Carninci, Akira Ohtake, Kei Murayama, Yasushi Okazaki
Publikováno v:
npj Genomic Medicine, Vol 9, Iss 1, Pp 1-12 (2024)
Abstract Repeat expansions cause at least 50 hereditary disorders, including Friedreich ataxia and other diseases known to cause mitochondrial dysfunction. We identified a patient with NAXE-related mitochondrial encephalopathy and novel biallelic GGG
Externí odkaz:
https://doaj.org/article/4c622688009f4260844f138e0fda2dc8
Autor:
Amaral, Paulo, Carbonell-Sala, Silvia, De La Vega, Francisco M., Faial, Tiago, Frankish, Adam, Gingeras, Thomas, Guigo, Roderic, Harrow, Jennifer L, Hatzigeorgiou, Artemis G., Johnson, Rory, Murphy, Terence D., Pertea, Mihaela, Pruitt, Kim D., Pujar, Shashikant, Takahashi, Hazuki, Ulitsky, Igor, Varabyou, Ales, Wells, Christine A., Yandell, Mark, Carninci, Piero, Salzberg, Steven L.
Scientists have been trying to identify all of the genes in the human genome since the initial draft of the genome was published in 2001. Over the intervening years, much progress has been made in identifying protein-coding genes, and the estimated n
Externí odkaz:
http://arxiv.org/abs/2303.13996
Autor:
Masaru Ariura, Therese Solberg, Hirotsugu Ishizu, Hazuki Takahashi, Piero Carninci, Haruhiko Siomi, Yuka W. Iwasaki
Publikováno v:
Cell Reports, Vol 43, Iss 12, Pp 115020- (2024)
Summary: Piwi-interacting RNAs (piRNAs) are the main repressors of transposable elements (TEs) in animal germlines. In Drosophila, Piwi-piRNA complexes associate with nascent TE transcripts to drive heterochromatin formation and TE repression. Howeve
Externí odkaz:
https://doaj.org/article/a25f97deca35491a9450eb4753be0d4f
Autor:
Sílvia Carbonell-Sala, Tamara Perteghella, Julien Lagarde, Hiromi Nishiyori, Emilio Palumbo, Carme Arnan, Hazuki Takahashi, Piero Carninci, Barbara Uszczynska-Ratajczak, Roderic Guigó
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Long-read RNA sequencing is essential to produce accurate and exhaustive annotation of eukaryotic genomes. Despite advancements in throughput and accuracy, achieving reliable end-to-end identification of RNA transcripts remains a challenge f
Externí odkaz:
https://doaj.org/article/6f0dff57dab14db685b630a7d127b446
Publikováno v:
BioTechniques, Vol 33, Iss 2, Pp 306-309 (2002)
The quality of collections of expressed sequence tags and full-length cDNAs is adversely affected by the presence of “junk” clones derived from unspliced or partially spliced RNAs present in conventional total RNA preparations. One can overcome t
Externí odkaz:
https://doaj.org/article/d2c69b6c143b42d3a20a875e51c15081
Autor:
Y. Shibata, P. Carninci, K. Sato, N. Hayatsu, T. Shiraki, Y. Ishii, T. Arakawa, A. Hara, N. Ohsato, M. Izawa, K. Aizawa, M. Itoh, K. Shibata, A. Shinagawa, J. Kawai, Y. Ota, S. Kikuchi, N. Kishimoto, M. Muramatsu, Y. Hayashizaki
Publikováno v:
BioTechniques, Vol 31, Iss 5, Pp 1042-1049 (2001)
We have developed a method to overcome sequencing problems caused by the presence of homopolymer stretches, such as polyA/T, in cDNA libraries. PolyA tails are shortened by cleaving before cDNA cloning with type IIS restriction enzymes, such as GsuI,
Externí odkaz:
https://doaj.org/article/5268ae529b06428994623f0ef37088a3
Publikováno v:
BioTechniques, Vol 30, Iss 6, Pp 1250-1254 (2001)
We have developed the single-strand linker ligation method (SSLLM), which uses DNA ligase to add a dsDNA linker to singlestranded (ss) full-length cDNA. The linkers have random 6-bp (dN6 or dGN5) 3′ overhangs that can ligate to any cDNA sequence, t
Externí odkaz:
https://doaj.org/article/c920e5ca0545411d87facd86a8786d62
Autor:
Harshita Sharma, Matthew N. Z. Valentine, Naoko Toki, Hiromi Nishiyori Sueki, Stefano Gustincich, Hazuki Takahashi, Piero Carninci
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract RNA structure folding largely influences RNA regulation by providing flexibility and functional diversity. In silico and in vitro analyses are limited in their ability to capture the intricate relationships between dynamic RNA structure and
Externí odkaz:
https://doaj.org/article/1637cefee94c4fa7afc213d5a0c824ed